Results 241 to 250 of about 18,323,172 (295)

Antibody framework engineering enables augmented cytokine receptor signaling capacities of bispecific single domain antibody-based IL-21 mimetics. [PDF]

MAbs
Lipinski B, Unmuth L, Tran THH, Harwood J, Arras P, Becker S, Harwardt J, Guarnera E, Helming L, Zaynagetdinov R, Bertoldo D, Rajpal A, Elter D, Pekar L, Evers A, Zielonka S.   +15 more
europepmc   +1 more source

Memory CD4⁺ T cells in chronic uveitis: pathogenicity, mechanisms, and therapeutic implications. [PDF]

Front Immunol
Shayan M, Mahaling B, Chen Y.
europepmc   +1 more source

Defining the mechanisms of neuroinflammation and antepartum neuroprotection in human neural progenitor cells and microglia. [PDF]

AJOG Glob Rep
Ligon SE, Leonard KM, Damicis JR, Bastian MK, Free KE, Kinsman HJ, Burd I, Napolitano PG, Ieronimakis N.   +8 more
europepmc   +1 more source

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Regulation of alloreactivity in vivo by IL-4 and the soluble IL-4 receptor

The Journal of Immunology, 1991
Abstract Although numerous in vitro studies have demonstrated that cytokines are involved in the generation of alloreactive effector cells, the role of these regulatory substances in vivo is less well defined. We have recently cloned and expressed cDNAs encoding both membrane bound and soluble forms of the murine IL-4R.
W C, Fanslow, K N, Clifford, L S, Park, A S, Rubin, R F, Voice, M P, Beckmann, M B, Widmer   +6 more
openaire   +2 more sources

The IL-4 Receptor — Signaling Mechanisms

1994
Interleukin-4 (IL-4) is a multifunctional cytokine that is a member of the hematopoietin family1. Its structure consists of a bundle of four left handed α helices in which the first and second and the third and fourth helices are connected by long over hand loops2,3,4,5.
A, Keegan, K, Nelms, W E, Paul
openaire   +2 more sources