Results 121 to 130 of about 17,201,482 (284)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Il quadro economico e produttivo in Europa

, 2015
Il contributo descrive la geografia produttivo-commerciale del settore tessile-abbigliamento, tassello importante dell’economia manifatturiera europea, che conta oltre 200.000 imprese e circa 1,6 milioni di addetti, che generano circa 5 milioni di posti ...
SIMONETTI, LUCIA
core  

Il Servizio sanitario regionale in Liguria: una regione del sud al nord?

Sommario: 1. Il Sistema sanitario accentrato della Liguria tra caratteristiche territoriali e sociodemografiche. - 2. I nuovi criteri di riparto del FSN 2023 e il finanziamento sani- tario nella regione più anziana d’Italia. - 3.
A. Pitino
core   +1 more source

Il virus lombardo (Cosa spiega l’elevata mortalità in Lombardia da Covid-19 : la scarsità di posti in terapia intensiva)

, 2020
Published online 3 April 2020Il numero di morti causati dal COVID-19 in Lombardia è altissimo (7199 al 31 marzo) rispetto al numero di contagiati ufficiali secondo la Protezione Civile (43208 alla stessa data). Stando a questi numeri il tasso di letalità
RUSTICHINI, Aldo, FAVERO, Carlo, ICHINO, Andrea   +2 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

IL-4R/IL-5 dependent increase of lung-resident CD169⁺ macrophages in microfilaremic mice.

, 2019
Lungs were recovered from naive and L. sigmodontis infected WT, ΔdblGata1 and Il-4ra-/-/Il-5-/- BALB/c mice at 70 days p.i.. Precision cut lung slices (PCLS) were prepared for confocal microscopy analysis.
Frédéric Landmann (5650090), Nathaly Vallarino-Lhermitte (3172725), Marc P. Hübner (7252544), Stefan J. Frohberger (6236105), Achim Hoerauf (65649), Estelle Remion (7330235), Coralie Martin (171733), John Le Quesne (594408), Leo M. Carlin (7330238), Frédéric Fercoq (3172713)   +9 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Severe hypereosinophilic syndrome successfully treated with a monoclonal antibody against interleukin 5 receptor α – benralizumab

Central European Journal of Immunology, 2021
Joanna Kosałka-Węgiel, Mamert Milewski, Andżelika Siwiec, Magdalena Strach, Bogdan Ochrem, Mariusz Korkosz   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Il ritratto di Alfonso il Magnanimo nell'inedito Novencarmen di Lorenzo Valla

, 2014
La relazione illustra le modalità di rappresentazione e celebrazione di Alfonso il Magnanimo nell'inedito poema polimetrico di Lorenzo Valla intitolato ...
IACONO, ANTONIETTA
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