Results 121 to 130 of about 1,825,564 (240)

Role of IL-5 in eosinophil-associated diseases and prospects for multi-target therapy. [PDF]

Front Immunol
Ou W, Wang Y, Hou C, Hou S, Zhou Y, Wang J, Wang Q.   +6 more
europepmc   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

72. Factors That Influence Leadership Roles in Plastic Surgery

Plastic and Reconstructive Surgery, Global Open, 2023
Narainsai K. Reddy, MS, Kristof Gutowski, BS, Alice Yau, BS, Marina A. Lentskevich, BS, Sofia Aronson, MD, Anitesh Bajaj, BS, Joshua P. Weissman, BBA, Scott Crawford, PhD, Arun K. Gosain, MD   +8 more
doaj   +1 more source

Depemokimab: A twice yearly anti-IL 5 biologic for chronic rhinosinusitis with nasal polyps (CRSwNP) - A narrative review. [PDF]

Hum Vaccin Immunother
Park MJ, Han JK, Lam KK.
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Beyond Eosinophil Depletion: IL-5 as a Context-Dependent Regulator of Airway Immune Networks. [PDF]

Int J Mol Sci
Cheng SL.
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

IL-5 CAR-T cell therapy induces effective remission in hypereosinophilic disorders. [PDF]

J Hematol Oncol
Wu Y, Zhang R, Sun B, Chen G, Xu F, Chen X, Zeng J, Shen D, Shi F, Pan S, Yao B, Tang H, Shao Z, Wu Q, Shao J, Zhang C, Wang D, Hu Y, Ying S.   +18 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Immune response of mice to Echinococcus multilocularis infection after therapy with amphotericin B colloidal dispersion

Helminthologia, 2007
Porubcová J., Dvorožňáková E., Ševčíková Z.   +2 more
doaj   +1 more source