Results 21 to 30 of about 80,028,732 (285)
Differential Regulation of Human IL-7 Receptor α Expression by IL-7 and TCR Signaling [PDF]
Abstract IL-7Rα is essential for the development and homeostatic maintenance of mature T cells. Studies in humans and mice have shown that IL-7Rα expression is reduced by its cognate cytokine, IL-7, and Ag, suggesting that active regulation of IL-7 responsiveness is necessary to balance T cell numbers.
Alves, Nuno L. +3 more
openaire +3 more sources
Different methods for detecting serum markers in patients with acute graft versus host disease
Objective To clarify the consistency of the results of the 2 methods for detecting serum biomarkers in patients with acute graft versus host disease (aGVHD) in order to screen out biomarkers with clinical value and to establish a biomarker screening ...
CHEN Ting +4 more
doaj +1 more source
IL-7 Induces Myelopoiesis and Erythropoiesis [PDF]
Abstract IL-7 administration to mice was previously reported to increase the mobilization of progenitor cells from marrow to peripheral sites. We now report that IL-7 increases the number of mature myeloid and monocytic cells in spleen and peripheral blood.
Francesca B, Aiello +5 more
openaire +2 more sources
Evaluation of pre-treatment serum levels of IL-7 and GM-CSF in colorectal cancer patients [PDF]
Background: Survival of Colorectal cancer (CRC) patients is considerably stage-dependent therefore, early diagnosis is a pivotal factor in decreasing mortality and morbidity associated with this cancer.
Mehdi Taghipour Fard Ardekani +6 more
doaj
Uterine leiomyomas are common benign tumors developing from smooth muscle tissues, often leading to infertility and recurrent abortions. Pregnancy and development of uterine fibroids are characterized by an unusual rate of myometrium growth ...
V. I. Konenkov +5 more
doaj +1 more source
The role of IL-7 in Immunity and Cancer [PDF]
Interleukin-7 (IL-7) is a cytokine that has been known since long in immunology, mainly regarding its effects on T-cells and B-cells. IL-7 has been demonstrated to be necessary for both B-cell and T-cell proliferation and lack of IL-7 causes immature immune cell arrest.
Jack, Lin +6 more
openaire +2 more sources
The aim of present work was to evaluate the effect of mesenchymal stromal cells (MSCs) from lymphoma patients on the in vitro and in vivo homeostatic proliferation of lymphocytes.
E. V. Batorov +8 more
doaj +1 more source
IL-7 in human health and disease [PDF]
IL-7 plays many essential roles in human health and disease. Congenital deficiencies in IL-7 signaling result in profound immunodeficiency, polymorphisms in IL7Rα modulate susceptibility to autoimmune disease, and acquired somatic activating mutations in IL7Rα contribute to neoplastic transformation in B cell and T cell leukemia.
Wangko, Lundström +2 more
openaire +2 more sources
7. N’est-il d’histoire que d’historiens?
Quand est-on historien ? Quand fait-on de l’histoire ? Faut-il être l’un pour faire l’autre ? Sous la présidence d’un historien, une quinzaine de représentants des sciences humaines et sociales pratiquées à l’université Paris 1 Panthéon-Sorbonne ont ...
Virginie Barrusse +14 more
doaj +1 more source
Effects of IL-7 on human lymphocytes [PDF]
Interleukin-7 (IL-7) is known as a growth factor for pre B-cell and mature T-cells in human. But in leukemic cells, IL-7 effect is variously reported. To investigate the effect of IL-7 on the cells of childhood acute leukemia we used 3H-Thymidine assay.
H S, Kim +3 more
openaire +2 more sources

