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乳腺超声联合血清IL-7R、GSTM5水平在乳腺结节良恶性鉴别诊断中的应用
Zhongguo shiyan zhenduanxue目的探讨乳腺超声联合血清白细胞介素-7受体（IL-7R）、谷胱甘肽S-转移酶Mu5（GSTM5）水平在乳腺结节（BN）良恶性鉴别诊断中的应用。方法选取2023年5月至2024年12月石家庄市妇幼保健院收治的108例女性BN患者作为研究对象，术前均行乳腺超声检查，以病理检查结果为金标准，分为恶性结节（恶性组，41例）和良性结节（良性组，67例）。酶联免疫吸附试验（ELISA）法检测血清IL-7R、GSTM5水平；受试者工作特性曲线（ROC）评估乳腺超声、血清IL-7R和GSTM5水平对BN良恶性的诊断价值；
曹美美 +4 more
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Generation of Affimer reagents for targeting the IL-7/IL-7R signalling
, 2019 Interleukin (IL)-7 is a cytokine involved in the pathogenesis of certain haematological malignancies and several autoimmune diseases. IL-7 bind to the IL-7R, an heterodimer constituted by IL-7Ra and the common-g chains, expressed by CD4 T-cells and ...
Perez Witzke, Daniel Alberto
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Thesis (Ph. D.)--University of Rochester. School of Medicine and Dentistry. Dept. of Pharmacology and Physiology, 2009.Opioids are known to affect both immune cell functions and development.
Bidlack, Jean M., Khimich, Maxim
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The synergistic role of IL-7/IL-7R and ZEB2 in breast cancer
Breast cancer remains a significant health challenge in Canada, necessitating the continued exploration of novel therapeutic strategies. This thesis investigates the role of two key players, Zinc Finger E-box Binding Homeobox 2 (ZEB2 transcription factor) and Interleukin-7 Receptor (IL-7R), in breast cancer progression and therapeutic response.
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Pharmacokinetics of an anti-IL-7R ADC for CNS-infiltrating ALL therapy
Annual Scientific Meeting of The Japanese Society of Clinical Pharmacology and Therapeuticsopenaire +1 more source
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Significance of IL-7 and IL-7R in RA and autoimmunity
Autoimmunity Reviews, 2022While physiological levels of IL-7 are essential for T cell proliferation, survival and co-stimulation, its escalated concentration has been associated with autoimmune diseases such as Rheumatoid arthritis (RA). Expression of IL-7 and IL-7R in RA monocytes is linked to disease activity score and TNF transcription.
Anja, Meyer +2 more
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