Results 31 to 40 of about 4,555,739 (141)
, 2023 High infiltration of tumor-associated macrophages (TAMs), which contribute to the progression of several cancer types, is correlated with poor prognosis of esophageal squamous cell carcinoma (ESCC).
Takayuki Kodama +33 more
core +1 more source
PLoS Pathogens, 2021 Inflammatory factors and type I interferons (IFNs) are key components of host antiviral innate immune responses, which can be released from the pathogen-infected macrophages. African swine fever virus (ASFV) has developed various strategies to evade host
Jiangnan Li +12 more
doaj +1 more source
Haematologica, 2023 Little is known about the transition mechanisms that govern early lymphoid lineage progenitors from common lymphoid progenitors (CLP). Pellino2 (PELI2) is a newly discovered E3 ubiquitin ligase, which plays important roles in inflammation and the immune
Yan Xu +12 more
doaj +1 more source
A key role for IL‐7R in the generation of microenvironments required for thymic dendritic cells [PDF]
Immunology & Cell Biology, 2017 Interleukin‐7 receptor (IL‐7R) signaling is critical for multiple stages of T‐cell development, but a role in the establishment of the mature thymic architecture needed for T‐cell development and thymocyte selection has not been established. Crosstalk signals between developing thymocytes and thymic epithelial cell (TEC) precursors are critical for ...
Amanda J Moore +7 more
openaire +2 more sources
Allergy & Rhinology, 2015 Background Interleukin 7R (IL-7R), a cytokine receptor gene, plays an important role in the development of innate and adaptive inflammatory response in asthma etiology. Objective IL-7R is a heterodimeric protein composed of α chain and γ chain.
Shweta Sinha M.Sc. +2 more
doaj +1 more source
Scientific Reports, 2022 Interleukin 7 (IL-7) has been demonstrated regulating lymphangiogenesis, apoptosis, and proliferation. Whether IL-7 induce or inhibit autophagy in non-small cell lung cancer (NSCLC) are unknown.
Yunjia Zhu +3 more
doaj +1 more source
Decreased systemic IL-7 and soluble IL-7R alpha in multiple sclerosis patients
, 2012 Polymorphisms (single-nucleotide polymorphism (SNP)) in the interleukin-7 receptor-alpha (IL-7R alpha)/IL-7 pathway are associated with an increased risk to develop multiple sclerosis (MS).
Wierenga - Wolf, Annet +13 more
core +1 more source
Frontiers in Immunology, 2022 Systemic sclerosis (SSc) is the most common connective tissue disease causing pulmonary hypertension (PAH). However, the cause and potential immune molecular events associated with PAH are still unclear. Therefore, it is particularly essential to analyze
Jianxin Tu +5 more
doaj +1 more source
The Tetraspanin CD53 Regulates Early B Cell Development by Promoting IL-7R Signaling [PDF]
The Journal of Immunology, 2020 Abstract The tetraspanin CD53 has been implicated in B cell development and function. CD53 is a transcriptional target of EBF1, a critical transcription factor for early B cell development. Further, human deficiency of CD53 results in recurrent infections and reduced serum Igs.
Zev J Greenberg +7 more
openaire +2 more sources
, 2012 (A, B) IEC were isolated from the colon of (A) Rag−IL-7R− and (A, B) Rag− mice. (B) Rag− IEC were stimulated with 20 ng/ml rec. IL-7 for 15 minutes or were left untreated. The levels of IL-7R expression and Stat5 phosphorylation (p-Stat5) were determined
Thomas Schüler (181192) +16 more
core +1 more source