Expression of mRNA for IL1 beta, IL6 and TGF beta 1 in developing human bone and cartilage. [PDF]
Using in situ hybridization, we investigated the expression of mRNA for interleukin-1 beta (IL1 beta), interleukin-6 (IL6), and transforming growth factor-beta-1 (TGF beta 1) in sections of developing bone in human osteophytes. The expression was related to the cellular activity of alkaline phosphatase to aid in the identification of pre-osteoblast ...
R A, Dodds +3 more
openaire +3 more sources
Background: Evaluating the biomarkers during orthodontic therapy allows us to monitor the effectiveness of the treatment, anticipate the future outcome, and also individualize the treatment according to the response of tissue to different force intensities.
Kumar, Barun D. +4 more
openaire +3 more sources
FABP4 regulates inflammation and lipid transport via PPARγ signaling pathway in goose primary hepatocytes [PDF]
Unlike human nonalcoholic fatty liver disease, fatty liver in geese do not induce inflammation even under severe steatosis, making it a unique model for studying hepatic lipid accumulation.
Xu Liu +8 more
doaj +2 more sources
Contribution of host-related immune factors to frequency and severity of infections in lung transplant recipients [PDF]
Background Lung transplantation (LTx) is associated with an increased risk of infection, causing notable morbidity and mortality at all phases post-transplantation.
Jiri Kufa +7 more
doaj +2 more sources
Rat pro-inflammatory cytokine and cytokine related mRNA quantification by real-time polymerase chain reaction using SYBR green [PDF]
Background Cytokine mRNA quantification is widely used to investigate cytokine profiles, particularly in small samples. Real-time polymerase chain reaction is currently the most reliable method of quantifying low-level transcripts such as cytokine and ...
Chancerelle Yves +8 more
doaj +2 more sources
Administration of Adipose-Derived Stem Cells After the Onset of the Disease Does Not Lower the Levels of Inflammatory Cytokines IL1 and IL6 in a Rat Model of Necrotizing Enterocolitis [PDF]
Background/Objectives: Research on the roles of stem cells in necrotizing enterocolitis (NEC) has primarily focused on the effects of bone marrow- and amniotic fluid-derived stem cells in mitigating the clinical manifestations of the disease. However, the potential of adipose tissue-derived stem cells (ADSCs) remains unexplored in this context. The aim
Marek Wolski +6 more
openaire +4 more sources
Deciphering the Inflammatory Network in Pediatric Recurrent Tonsillitis: The Role of TRAF6, IRAK1, and miR‐146a‐5p [PDF]
Abstract Objective To investigate the role of TNF receptor‐associated factor 6 (TRAF6), interleukin 1 receptor‐associated kinase 1 (IRAK1), and miR‐146a‐5p expression levels in the pathogenesis of recurrent tonsillitis. Study Design Case‐control study. Setting The study was conducted at the Department of Otorhinolaryngology, Muğla Training and Research
Ömer Faruk Güzel +3 more
wiley +2 more sources
Evaluation of salivary and serum Exosomal mRNAs as biomarkers for the diagnosis and prognosis of oral squamous cell carcinoma [PDF]
Minimally-invasive or non-invasive biomarkers from serum and saliva hold significant promise for real-time monitoring of oral squamous cell carcinoma (OSCC).
Sarwareddy Kartik Kumar +7 more
doaj +2 more sources
Exploratory Analysis of the Inhibitory Effects of Propranolol on NLRP3 and Pyrin Inflammasomes [PDF]
Objective Propranolol, a nonselective beta receptor blocking agents, impacts cAMP levels and is commonly used to treat hypertension and hemangioma in children and adults. Although there are reports indicating its anti‐inflammatory properties, the exact mechanism is not fully understood. Methods Murine and human monocytes and macrophages were exposed to
Renske J. de Jong +13 more
wiley +2 more sources
Imbalance of Pro and Anti-Inflammatory Cytokines in Rheumatoid Arthritis in Iraqi Patients
Background: Rheumatoid arthritis is an autoimmune chronic inflammatory illness that affects the whole body and is characterized by non-articular involvement and inflammatory arthritis.
Shakir M. Salih, Sevki A. Adam
doaj +2 more sources

