Tocotrienol supplementation in postmenopausal osteoporosis: evidence from a laboratory study
OBJECTIVE: Accelerated bone loss that occurs in postmenopausal women has been linked to oxidative stress and increased free radicals. We propose the use of antioxidants to prevent and reverse postmenopausal osteoporosis.
Norliza Muhammad +4 more
doaj +2 more sources
Effect of photobiomodulation therapy on regulating reparative processes of chronic wounds at the inflammation stage [PDF]
Introduction. Chronic wounds remain a major burden for patients and healthcare systems worldwide. Photobiomodulation therapy has demonstrated effectiveness as a physical method to support wound healing. Objective.
Rostislav Shevchenko +5 more
doaj +2 more sources
Preoperative Serum IL6, IL8, and TNF-α May Predict the Recurrence of Hepatocellular Cancer
Purpose. As we all know, curative resection remains the only effective treatment for hepatocellular cancer (HCC). However, systemic inflammatory response syndrome always correlates with surgery, which may impose an impact on the clinical outcome of HCC ...
Huayong Cai +7 more
doaj +2 more sources
The Effects of Antifungal Azoles on Inflammatory Cytokine Production in Human Keratinocytes
: Introduction & Objective: Azoles drugs are being used successfully in treatment of fungal infections. Recently, immunosuppressive effects of some of these agents have been reported. Keratinocytes, as the major cells of the skin, have an important role
K Zomorodian +3 more
doaj +1 more source
A study of the production of the selected cytokines interleukin 1, interleukin 6, and tumour necrosis factor by certain tumours and tumour cell lines [PDF]
An investigation was carried out to examine the production of the inflammatory cytokines IL1, IL1, IL6, TNF, and TNF in two tumour cell lines, the MCF-7 breast cell line and the T-24 bladder cell line, and in samples of breast, bladder, lung and ovarian ...
Chambers, George
core +4 more sources
Pro-Inflammatory Properties of Salivary Gland-Derived Fibroblasts—Implications in Sjögren’s Disease [PDF]
Salivary gland dysfunction is a hallmark of Sjögren’s disease (SjD). Here, we investigated the pro-inflammatory properties of salivary gland-derived fibroblasts (SGF) that were cultured from minor salivary gland (MSG) tissues of patients with SjD and ...
Matthias Brunner +15 more
doaj +2 more sources
Inflammatory Treatment Used to Mimic Osteoarthritis and Patients’ Synovial Fluid Have Divergent Molecular Impact on Chondrocytes In Vitro [PDF]
Osteoarthritis (OA) is a chronic disease characterized by joint tissue disruption and inflammation with a paucity of therapeutic options. Chondrocyte in vitro models are commonly used as the first step in evaluating new approaches and rely on the ...
Federico Valli +14 more
core +1 more source
Serum Levels of Interleukin-1 Alpha and Interleukin-6 in Acute Coronary Syndrome Patients
Background:Cytokines are responsible for the modulation of immunological and inflammatory processes and play a significant role in the pathogenesis of acute coronary syndrome patients (ACS).
Mohammed O Hamzah, Kismat M Turki
doaj +6 more sources
Suppression of IL1β stimulated genes in hRORβ/MG63 clone.
Inflammatory cytokine IL1β was treated into WT or OE RORβ/MG63 cells for 24 hr with 2nM. The mRNA expression level of IL6, MMP3 and ADAMTS4 was significantly increased by IL1 stimulation but it was protected in RORβ OE cells.
Patrick R. Griffin (554018) +1 more
core +1 more source
SIGIRR Downregulation and Interleukin-1 Signaling Intrinsic to Renal Cell Carcinoma
Renal cell carcinoma is highly inflamed, and tumor cells are embedded into a microenvironment enriched with IL1. While inflammatory pathways are well characterized in the immune system, less is known about these same pathways in epithelial cells; it is ...
Maria Elena Mantione +7 more
doaj +1 more source

