Results 191 to 200 of about 731,570 (316)

Diacerein Disrupts Testicular Homeostasis: The Essential Role of Basal Cytokines in Maintaining Sertoli Cell Integrity and the Immune Microenvironment

Andrology, EarlyView.
ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus, André Acácio Souza da Silva, Olumide Stephen Akinsomisoye, Erick J. R. Silva, Paulo Sérgio Cerri, Salmo Azambuja de Oliveira, Estela Sasso‐Cerri   +6 more
wiley   +1 more source

Periodontal inflammation: A clinically significant and underrecognized cardiovascular risk factor-The Endothelial Risk Score (ERS): A narrative review with conceptual framework development. [PDF]

Am Heart J Plus
Nwhator SO, Ogunwemimo MT, Akinyele OA, Adetunji TA, Onabanjo OA, Ogunleye BA, Adewole KO, Adewole OM, Ojo IO, Ogundiran T, Nwhator PA.   +10 more
europepmc   +1 more source

Hand and Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE@home) for Adults With Chronic Stroke: Protocol for a Randomized Controlled Trial. [PDF]

JMIR Res Protoc
Somville M, Rosselli Z, Ducoffre E, Arnould C, Bleyenheuft Y, Saussez G.   +5 more
europepmc   +1 more source

Mitragynine and Morphine Stabilize Different Conformations of the μ‑Opioid Receptor as Revealed by Molecular Dynamics Simulation Studies. [PDF]

ACS Omega
Neupane NP, Mathews JT, Lingaraju S, You Y, Mathukumalli K, Das J.   +5 more
europepmc   +1 more source

Novel Variants in PUS7 Associated With Intellectual Disability and Growth Retardation: Expanding the Clinical Spectrum in 13 Patients

Clinical Genetics, EarlyView.
Novel variants in PUS7 associated with intellectual disability and growth retardation: expanding the clinical spectrum in 13 patients. ABSTRACT Pseudouridylation is a frequent post‐transcriptional modification resulting in uridine isomerization in 5‐ribosyluracil, also called pseudouridine. This mechanism leads to RNA stability with an increase in base‐
Camille Bergès, Clément Sauvestre, Sophie Naudion, Catherine Vincent Delorme, Thomas Smol, Mélanie Rama, Stephanie Moortgat, Isabelle Maystadt, Rogier Kersseboom, Martina Wilke, Stefan Barakat, Yoann Vial, Laurence Perrin, Sandrine Passemard, Farooq Ahmad, Muhammad Umair, Tobias Haack, Mona Grimmel, Alma Kuechler, Anne Slavotinek, Patrick Devine, Ugur Hodoglugil, Faisal Zafar, Erum Afzal, Tracy Dudding‐Byth, Guillaume Jouret, Lucas Herissant, Stephanie Efthymiou, Henry Houlden, Marine Legendre, Vincent Michaud   +30 more
wiley   +1 more source

Chemical Constituents and Biological Potentials of Teucrium scordium subsp. scordioides Extracts: In Vitro Experimental and In Silico Perspectives. [PDF]

ChemistryOpen
Akgul BH, Yagi S, Cetiz MV, Saka E, Zengin G, Llorent-Martínez EJ, Gómez-Torres M, Yapıcı I, Gulcin I, Yıldıztugay E.   +9 more
europepmc   +1 more source

The Role of Continuous Glucose Monitoring in Managing Hyperglycaemia First Detected in Pregnancy: A Narrative Review

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Hyperglycaemia first diagnosed in pregnancy (HIP) is the most common medical condition affecting pregnancy, affecting up to 40% of pregnancies in some countries. The global incidence of HIP is increasing owing to rising rates of overweight and obesity, advanced maternal age, and early screening for HIP.
Emmanuel Cosson, Laura Chabrol Haas, Fleur Levrat‐Guillen   +2 more
wiley   +1 more source

Interaction with CYP20-3 limits OPDA flux into jasmonate biosynthesis in wounded leaves of arabidopsis grown at eCO₂. [PDF]

Front Plant Sci
Redl A, Gabriel J, van Dam NM, Bede JC.
europepmc   +1 more source

Quantifying Species‐ and Community‐Level Predation by Carabids on Pests and Beneficials in Wheat and Beet Fields

Entomologia Experimentalis et Applicata, EarlyView.
Using a model that translates qualitative prey detection data (presence/absence in predator gut contents) into quantitative predation rates, we estimate species‐specific diets of nine carabid species across three cropping contexts (wheat, sugar beet, and fodder beet) for five prey types.
Marion Rosec, Yann Tricault, Sylvain Poggi, Elsa Canard, Ambre Sacco Martret de Préville, Pierre Gendron, Lena Barascou, Marianne Doehler, Ségolène Buzy, Aurore Arnoult, Anne Le Ralec, Manuel Plantegenest, Abel Masson   +12 more
wiley   +1 more source

Using physical elicitors to enhance pigment production in <i>Streptomyces</i> sp. VITGV38, and bioactivity and molecular docking studies of the extracted pigment-related compounds. [PDF]

BioTechnologia (Pozn)
Soniyagandhi E, Christopher JG.
europepmc   +1 more source