Results 191 to 200 of about 1,458,458 (304)

A distinct gene expression mechanism for d‐amino acid utilization in hyperthermophilic archaeon Pyrococcus horikoshii

open access: yesThe FEBS Journal, EarlyView.
The genes PH0137, PH0138, and PH0140 form a cluster in the genome of Pyrococcus horikoshii. The PH0140 gene encodes a transcription factor identified as a d‐amino acid‐responsive regulatory protein (DARP). In feast mode, l‐Ile‐bound DARP binds to the promoter and represses transcription of PH0137 and PH0138. In famine mode, DARP binds to d‐allo‐Ile and
Ryushi Kawakami   +6 more
wiley   +1 more source

Depletion of individual dietary amino acids induce distinct metabolic and chromatin states. [PDF]

open access: yesJ Biol Chem
Haws SA   +10 more
europepmc   +1 more source

Bioelectrical Impedance in Pediatric Dialysis: Clinical Applications, Limitations, and Opportunities

open access: yesHemodialysis International, EarlyView.
ABSTRACT Background Optimizing fluid and nutritional management is a cornerstone of care for children with end‐stage kidney disease on dialysis. Inaccurate assessment of hydration status contributes to hypertension, fluid overload, and increased cardiovascular risk, while masking important changes in muscle and fat compartments that affect growth and ...
Marisa Juarez‐Calderon   +2 more
wiley   +1 more source

Incidence and Characteristics of HBV Reactivation‐Related Events Following HBsAg Seroclearance: Long‐Term Follow‐up of a Population‐Based Cohort in Japan

open access: yesHepatology Research, EarlyView.
In a population‐based cohort in Japan, HBV reactivation‐related events were observed after HBsAg seroclearance, including one virologically confirmed hepatic flare occurring spontaneously without chemotherapy or immunosuppression. These findings indicate that HBsAg seroclearance does not always represent complete viral eradication, supporting the need ...
Kazumi Yamasaki   +7 more
wiley   +1 more source

Treatment durability, satisfaction and quality of life in virologically suppressed HIV‐1 people switching to doravirine: Results from the French study DoraVIH

open access: yesHIV Medicine, EarlyView.
Abstract Objectives In Europe, most people with HIV‐1(PWH) achieve virologic suppression with effective and well‐tolerated antiretroviral therapies (ART). In this context, patient‐reported outcomes (PRO) are increasingly important for evaluating ART benefits.
Spire Bruno   +9 more
wiley   +1 more source

Polymorphic myopathological findings in a 77‐year‐old woman with oculo‐bulbo‐facial and distal weakness

open access: yes
Brain Pathology, EarlyView.
Michele Tosi   +6 more
wiley   +1 more source

Missed opportunities to prevent HIV acquisition with pre‐exposure prophylaxis: A mixed methods study of people with recently acquired HIV in the United Kingdom

open access: yesHIV Medicine, EarlyView.
Abstract Objectives To explore missed opportunities for PrEP use among people with recently acquired HIV in the United Kingdom. Methods Data were derived from CASCADE, an international, longitudinal, mixed‐methods study of adults (≥16 years) with recently acquired HIV (≤12 months).
Argyro Karakosta   +145 more
wiley   +1 more source

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