Results 31 to 40 of about 731,570 (316)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Absorção, teatralidade e a tradição da pintura francesa na obra de Henri Matisse.

open access: yesARS
RESUMO O artigo examina as noções de “absorção” e “teatralidade” propostas por Michael Fried e retomadas por Yve-Alain Bois nos textos em que escreveu sobre a obra de Henri Matisse.
Ilê Sartuzi
doaj   +1 more source

Il linguaggio artistico: il lessico

open access: yesLinguistica, 2006
Il presente lavoro tratta della terminologia delle arti e in particolare del lessico della pittura, della scultura e dell' architettura. L' articolo discute ed esamina i principali procedimenti formativi dell' italiano contemporaneo, come la suffissazione , la prefissazione e la composizione delle parole, in relazione alla terminologia delle arti.
openaire   +5 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

GENETIC FACTORS OF CLIMATE IN THE CRIŞUL NEGRU HYDROGRAPHIC BASIN [PDF]

open access: yesAnalele Universităţii din Oradea: Seria Geografie, 2013
This paper summarizes the genetic factors that determine the climate from the Crişul Negru hydrographic basin, namely the solar radiation, the movement of air masses and the active subjacent surface.
Viorel GALIŞ, Marius ILE
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Uzamış Kas Güçsüzlüğü ile Seyreden Acetamiprid Zehirlenmesi [PDF]

open access: yes, 2017
Yeni bir insektisid grubu olan neonikotinoidler insanlar için düşük toksisiteli olarak kabul edilmektedir. Bu sunumda 41 yaşında intihar amaçlı acetamiprid oral alımı sonrası uzun süreli kas güçsüzlüğü nedeniyle yoğun bakım şartlarında takip edilmiş ve ...
Dogan, Rafi   +9 more
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Pedagogía institucionista y educación social en Castilla y León

open access: yesHistoria de la Educación, 2013
El presente trabajo de investigación historiográfica sobre el desarrollo e influencia del institutucionismo pedagógico en Castilla y León ha pretendido hacer hincapié en dos coordenadas generales.
Leoncio VEGA GIL
doaj  

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