Results 11 to 20 of about 195,947 (313)
Different approaches to Imaging Mass Cytometry data analysis. [PDF]
Bioinform Adv, 2023 Summary Imaging Mass Cytometry (IMC) is a novel, high multiplexing imaging platform capable of simultaneously detecting and visualizing up to 40 different protein targets. It is a strong asset available for in-depth study of histology and pathophysiology of the tissues.
Milosevic V.
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Imaging Mass Cytometry Compensation Slide Acquisition v1 [PDF]
, 2020 This SOP describes the slide acquisition for spill-over correction of Imaging Mass Cytometry experiments. The protocol makes use of the compensation slide, which was prepared previously following the SOP: “HuBMAP_Protocol_3_Compensation_Slide_Preparation.pdf” to measure each conjugated antibody individually and to record all observed spill-over.
Michelle Daniel, Marda Jorgensen
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Dice-XMBD: Deep Learning-Based Cell Segmentation for Imaging Mass Cytometry [PDF]
Frontiers in Genetics, 2021 Highly multiplexed imaging technology is a powerful tool to facilitate understanding the composition and interactions of cells in tumor microenvironments at subcellular resolution, which is crucial for both basic research and clinical applications.
Xu Xiao +11 more
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Imaging mass cytometry reveals tissue-specific cellular immune phenotypes in the mouse knee following ACL injury. [PDF]
Osteoarthr Cartil Open, 2023 Objective: To develop an imaging mass cytometry method for identifying complex cell phenotypes, inter-cellular interactions, and population changes in the synovium and infrapatellar fat pad (IFP) of the mouse knee following a non-invasive compression ...
South SM +8 more
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Multidimensional profiling of drug‐treated cells by Imaging Mass Cytometry [PDF]
FEBS Open Bio, 2019 In pharmaceutical research, high‐content screening is an integral part of lead candidate development. Measuring drug response in vitro by examining over 40 parameters, including biomarkers, signaling molecules, cell morphological changes, proliferation indices, and toxicity in a single sample,
Bouzekri, Alexandre +2 more
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IMC-Denoise: a content aware denoising pipeline to enhance Imaging Mass Cytometry. [PDF]
Nat Commun, 2023 Multiplexed imaging technologies can reveal the complex cellular and molecular profiles of tissue. Here, the authors develop and implement a denoising pipeline to significantly enhance imaging mass cytometry quality and improve single-cell analyses.
Lu P +10 more
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Imaging Mass Cytometry Analysis of immune Checkpoint Inhibitor-Related Pneumonitis: A Case Report. [PDF]
Front Immunol, 2022 Immune checkpoint inhibitor-related pneumonitis (CIP) is a rare but well-recognized immune-related adverse event (irAE), causes 35% of irAE related deaths.
Cheng Y +8 more
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Cytometry Part A, 2017 AbstractImaging Mass Cytometry (IMC) is an expansion of mass cytometry, but rather than analyzing single cells in suspension, it uses laser ablation to generate plumes of particles that are carried to the mass cytometer by a stream of inert gas. Images reconstructed from tissue sections scanned by IMC have a resolution comparable to light microscopy ...
Qing Chang +5 more
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Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry
eLife, 2019 Multiple sclerosis (MS) is characterized by demyelinated and inflammatory lesions in the brain and spinal cord that are highly variable in terms of cellular content.
Valeria Ramaglia +12 more
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Imaging mass cytometry for high-dimensional tissue profiling in the eye. [PDF]
BMC Ophthalmol, 2021 Background Imaging mass cytometry (IMC) combines the principles of flow cytometry and mass spectrometry (MS) with laser scanning spatial resolution and offers unique advantages for the analysis of tissue samples in unprecedented detail.
Schlecht A +11 more
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