Results 21 to 30 of about 190,121 (278)

Standardization of suspension and imaging mass cytometry readouts for clinical decision making [PDF]

, 2023
Casanova R, Xu S, Sivapatham S, Jacobs A, Engler S, Tumor Profiler Consortium, Levesque MP, Dummer R, Bodenmiller B, Bodenmiller B, Chevrier S.   +10 more
europepmc   +2 more sources

LGG-13. UNRAVELING THE SPATIAL TUMOR MICROENVIRONMENT OF PEDIATRIC LOW-GRADE GLIOMAS USING IMAGING MASS CYTOMETRY [PDF]

Neuro Oncol
Augusto Faria Andrade, Romain Sigaud, Evan Puligandla, Bridget Liu, Elham Karimi, Simone Schmid, Florian Selt, Pablo Hernáiz Driever, Arend Koch, Felix Sahm, Philipp Sievers, Stefan M. Pfister, Olaf Witt, David Jones, David Capper, Logan A. Walsh, Nada Jabado, Till Milde   +17 more
europepmc   +3 more sources

Integrating AI-Powered Digital Pathology and Imaging Mass Cytometry Identifies Key Classifiers of Tumor Cells, Stroma, and Immune Cells in Non-Small Cell Lung Cancer. [PDF]

Cancer Res
Rigamonti A, Viatore M, Polidori R, Rahal D, Erreni M, Fumagalli MR, Zanini D, Doni A, Putignano AR, Bossi P, Voulaz E, Alloisio M, Rossi S, Zucali PA, Santoro A, Balzano V, Nisticò P, Feuerhake F, Mantovani A, Locati M, Marchesi F.   +20 more
europepmc   +3 more sources

The Second Transmembrane Domain of P2X7 Contributes to Dilated Pore Formation [PDF]

, 2013
Activation of the purinergic receptor P2X7 leads to the cellular permeability of low molecular weight cations. To determine which domains of P2X7 are necessary for this permeability, we exchanged either the C-terminus or portions of the second ...
A MacKenzie, A Surprenant, AN Shemon, B Gu, BC Suh, BJ Gu, BJ Gu, BM Saunders, BS Khakh, BS Khakh, C Andrei, C Marques-da-Silva, C Sun, C Virginio, Chengqun Sun, CP Lai, D Leon, D Zink, DS Emmett, DS Samways, E Adinolfi, E Bulanova, F Bretschneider, F Rassendren, G Girolomoni, H Gunosewoyo, HJ Bradley, HM Costa-Junior, HZ Hu, JS Wiley, K Schroder, KA Hillman, L Gudipaty, L Stokes, LC Denlinger, LC Denlinger, LE Browne, LH Jiang, LH Jiang, M Li, M Li, Michelle E. Heid, ML Gavala, ML Smart, MT Miras-Portugal, P Marin-Garcia, P Pelegrin, P Pelegrin, Peter A. Keyel, Pierre Bobé, Q Li, R Sluyter, RA North, Russell D. Salter, S Chaumont, S Kracun, S Locovei, S Penuela, S Roger, SD Ohlendorff, SD Silberberg, SL Fernando, SL Fernando, T Kawate, T Sugiyama, TM Egan, V Petrilli, W Duckwitz, Y Shinozaki   +68 more
core   +10 more sources

Case Report: Transformation From Cold to Hot Tumor in a Case of NSCLC Neoadjuvant Immunochemotherapy Pseudoprogression

Frontiers in Immunology, 2021
A 56-year-old male was diagnosed with right lung upper lobe squamous cancer with right hilar and mediastinum lymph node metastasis. After four cycles of neoadjuvant immunochemotherapy, reexamination by computed tomography showed progressive disease of ...
Wenxiao Jia, Hui Zhu, Qianqian Gao, Jian Sun, Fujian Tan, Qun Liu, Hongbo Guo, Hongbo Guo, Jinming Yu, Jinming Yu   +9 more
doaj   +1 more source

The proteomic analysis of breast cell line exosomes reveals disease patterns and potential biomarkers

Scientific Reports, 2020
Cancer cells release small extracellular vesicles, exosomes, that have been shown to contribute to various aspects of cancer development and progression. Differential analysis of exosomal proteomes from cancerous and non-tumorigenic breast cell lines can
Yousef Risha, Zoran Minic, Shahrokh M. Ghobadloo, Maxim V. Berezovski   +3 more
doaj   +1 more source

Interactions of Cisplatin and Daunorubicin at the chromatin level [PDF]

, 2020
Unexpectedly, the widely used anticancer agents Cisplatin (Cis-Pt) and Daunorubicin (Dauno) exhibited cell type- and concentration-dependent synergy or antagonism in vitro.
Bacsó, Zsolt, Firouzi Niaki, Erfaneh, Imre, László, Nánási, Péter Jr., Szabó, Gábor, Tarapcsák, Szabolcs, Van Acker, Thibaut, Vanhaecke, Frank   +7 more
core   +2 more sources

Mass Cytometry Imaging for the Study of Human Diseases—Applications and Data Analysis Strategies

Frontiers in Immunology, 2019
High parameter imaging is an important tool in the life sciences for both discovery and healthcare applications. Imaging Mass Cytometry (IMC) and Multiplexed Ion Beam Imaging (MIBI) are two relatively recent technologies which enable clinical samples to ...
Heeva Baharlou, Heeva Baharlou, Nicolas P. Canete, Nicolas P. Canete, Anthony L. Cunningham, Anthony L. Cunningham, Andrew N. Harman, Andrew N. Harman, Ellis Patrick, Ellis Patrick   +9 more
doaj   +1 more source

Single-cell western blotting. [PDF]

, 2014
To measure cell-to-cell variation in protein-mediated functions, we developed an approach to conduct ∼10(3) concurrent single-cell western blots (scWesterns) in ∼4 h.
Herr, Amy E, Hughes, Alex J, Kang, Chi-Chih, Schaffer, David V, Spelke, Dawn P, Xu, Zhuchen   +5 more
core   +2 more sources

MATISSE: a method for improved single cell segmentation in imaging mass cytometry

BMC Biology, 2021
Background Visualizing and quantifying cellular heterogeneity is of central importance to study tissue complexity, development, and physiology and has a vital role in understanding pathologies.
Matthijs J. D. Baars, Neeraj Sinha, Mojtaba Amini, Annelies Pieterman-Bos, Stephanie van Dam, Maroussia M. P. Ganpat, Miangela M. Laclé, Bas Oldenburg, Yvonne Vercoulen   +8 more
doaj   +1 more source