DNA-barcoded signal amplification for imaging mass cytometry enables sensitive and highly multiplexed tissue imaging. [PDF]
Nat Methods, 2023 Hosogane T, Casanova R, Bodenmiller B.
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Development of a high dimensional imaging mass cytometry panel to investigate spatial organization of tissue microenvironment in formalin-fixed archival clinical tissues. [PDF]
HeliyonTornaas S +8 more
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Frontiers in Immunology, 2021 A 56-year-old male was diagnosed with right lung upper lobe squamous cancer with right hilar and mediastinum lymph node metastasis. After four cycles of neoadjuvant immunochemotherapy, reexamination by computed tomography showed progressive disease of ...
Wenxiao Jia +9 more
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Interactions of Cisplatin and Daunorubicin at the chromatin level [PDF]
, 2020 Unexpectedly, the widely used anticancer agents Cisplatin (Cis-Pt) and Daunorubicin (Dauno) exhibited cell type- and concentration-dependent synergy or antagonism in vitro.
Bacsó, Zsolt +7 more
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Scientific Reports, 2020 Cancer cells release small extracellular vesicles, exosomes, that have been shown to contribute to various aspects of cancer development and progression. Differential analysis of exosomal proteomes from cancerous and non-tumorigenic breast cell lines can
Yousef Risha +3 more
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Mass Cytometry Imaging for the Study of Human Diseases—Applications and Data Analysis Strategies
Frontiers in Immunology, 2019 High parameter imaging is an important tool in the life sciences for both discovery and healthcare applications. Imaging Mass Cytometry (IMC) and Multiplexed Ion Beam Imaging (MIBI) are two relatively recent technologies which enable clinical samples to ...
Heeva Baharlou +9 more
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Label-Free Metabolic Classification of Single Cells in Droplets Using the Phasor Approach to Fluorescence Lifetime Imaging Microscopy. [PDF]
, 2019 Characterization of single cell metabolism is imperative for understanding subcellular functional and biochemical changes associated with healthy tissue development and the progression of numerous diseases.
Aghaamoo, Mohammad +4 more
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Imaging Mass Cytometry Data Acquisition v1 [PDF]
, 2020 This SOP describes the image acquisition with an Imaging Mass Cytometer (IMC or Hyperion). Prior to this protocol the IMC needs to be fully tuned to specifications (see “HuBMAP_Protocol_4_IMC_Tuning.pdf”). Additionally, every batch of samples stained with the same antibody-mix requires the acquisition of a compensation slide for spill over correction ...
Michelle Daniel, Marda Jorgensen
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Research Techniques Made Simple: Experimental Methodology for Imaging Mass Cytometry [PDF]
Journal of Investigative Dermatology, 2021 Technological advances in flow cytometry and the development of mass cytometry by time-of-flight (CyTOF) have led to progressive increases in the number of proteins and biochemical processes that can be simultaneously measured. The most recent development of these platforms, imaging mass cytometry (IMC), allows for the visualization of up to 40 unique ...
Sheida Naderi-Azad +4 more
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Mass Cytometric Analysis of Early-Stage Mycosis Fungoides
Cells, 2022 Mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma. Early-stage disease is characterized by superficial infiltrates of small- to medium-sized atypical epidermotropic T lymphocytes that are clonal related.
Nannan Guo +7 more
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