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Antiprotozoal agents as water soluble singlet oxygen photosensitizers: Imidazo[1,2-a]pyridine and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridine derivatives

Journal of Luminescence, 2017
Abstract In this study we report on the photophysical properties of some imidazo[1,2-a]pyridine and 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine derivatives and their efficiency as singlet oxygen photosensitizers in aqueous media. In aqueous solution, the wavelengths of maximum absorption are in the range of 269–307 nm, while the wavelengths of maximum ...
Ayman A. Abdel-Shafi   +3 more
openaire   +1 more source

Medicinal Attributes of Imidazo[1,2-a]pyridine Derivatives: An Update

Current Topics in Medicinal Chemistry, 2016
The imidazo[1,2-a]pyridine scaffold is recognized as a privileged structure as it represents a promising area for identification of lead structures towards the discovery of new synthetic drug molecules. Several commercial drugs such as Zolpidem, Olprinone, Soraprazan and many other compounds in biological testing and preclinical evaluation, illustrate ...
Nisha, Devi   +4 more
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Simple synthesis of substituted benzo[4,5]imidazo[1,2-a]pyridines

Russian Journal of Organic Chemistry, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
R. S. Begunov   +2 more
openaire   +1 more source

Efficient Synthesis of Imidazo[1,2‐a]pyridin‐3(2H)‐ones.

ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Mehdi Adib   +4 more
openaire   +1 more source

Multicomponent Synthesis of Imidazo[1,2-a]pyridines: Aerobic Oxidative Formation of C-N and C-S Bonds by Flavin-Iodine-Coupled Organocatalysis.

Organic Letters, 2020
Herein, we report an aerobic oxidative C-N bond-forming process that enables the facile synthesis of imidazo[1,2-a]pyridines and takes advantage of a coupled organocatalytic system that uses flavin and iodine.
Hayaki Okai   +3 more
semanticscholar   +1 more source

ChemInform Abstract: SYNTHESIS OF IMIDAZO(1,2‐A)PYRIDINES DIRECTLY FROM METHYL OR METHYLENE KETONES. IODINATION OF IMIDAZO(1,2‐A)PYRIDINES

Chemischer Informationsdienst, 1977
AbstractMethyl‐ oder Methylenketone (I) reagieren in Gegenwart von äquimolaren Mengen Jod in Dimethylsulfoxid mit 2‐Arninopyridin (II) oder seinen methylsubstituierten Derivaten in direkter Reaktion zu Imidazopyridinen (III).
N. O. SALDABOL, S. A. GILLER
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Aminomethylation of 2-(2-furyl)imidazo-[1,2-a]pyridine

Chemistry of Heterocyclic Compounds, 1971
The aminomethylation (morpholino- and piperidinomethylation) of 2-(2-furyl)imidazo[1,2-a]-pyridine proceeds primarily at the 3 position of the imidazopyridine system at equimolecular ratios of the reagents, but also proceeds at the 5 position of the furan ring when there is a slight excess of formaldehyde and amine.
N. O. Saldabol   +2 more
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ChemInform Abstract: IMIDAZO(1,2‐A)PYRIDINES ‐ NOVEL SUBSTITUTION REACTIONS

Chemischer Informationsdienst, 1977
AbstractNovel Substitution Reactions.
E. S. HAND, W. W. PAUDLER
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Synthesis and antiviral activity of imidazo[1,2-a]pyridines

European Journal of Medicinal Chemistry, 1999
Abstract Imidazo[1,2- a ]pyridines bearing a 3-(dithiolan-, dioxolan- or oxathiolan-2-yl) substituent were synthesized from the corresponding aldehydes. The dithiolanyl derivative 6a proved active against cytomegalovirus at an inhibitory concentration (IC 50 ) of 16 μM, whilethe oxathiolanyl compound 6c inhibited respiratory syncytial virus (IC ...
Mohammed Lhassani   +9 more
openaire   +1 more source

Chemoselective iodination of 6-substituted imidazo[1,2-a]pyridine

Chemistry of Heterocyclic Compounds, 2018
3- and 8-Iodoimidazo[1,2-a]pyridines were synthesized from imidazo[1,2-a]pyridine under different substitution conditions. The molecular electrostatic potential calculations were performed to investigate the chemoselectivity of the substitution reaction.
Chunshen Zhao   +5 more
openaire   +1 more source

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