Results 211 to 220 of about 339,340 (383)

The Biosynthesis of the Imidazole Ring of Histidine

, 1960
H.S. Moyed, Boris Magasanik
openalex   +1 more source

Targeting GPX4 to Induce Ferroptosis Overcomes Chemoresistance Mediated by the PAX8‐AS1/GPX4 Axis in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
PAX8‐AS1 drives chemoresistance in intrahepatic cholangiocarcinoma by activating NRF2‐mediated GPX4 transcription and stabilizing GPX4 mRNA via IGF2BP3. Targeting the PAX8‐AS1/GPX4 axis with a GPX4 inhibitor enhances the efficacy of gemcitabine and cisplatin in preclinical models, offering a promising strategy to overcome chemotherapy resistance in ...
Zhi‐Wen Chen, Ji‐Jun Shan, Mo Chen, Zong Wu, Yi‐Ming Zhao, Hong‐Xu Zhu, Xin Jin, Yi‐Xiu Wang, Yi‐Bin Wu, Zhen Xiang, Zhi‐Wen Ding, Zhen‐Hai Lin, Long‐Rong Wang, Lu Wang   +13 more
wiley   +1 more source

Structural and Spectroscopic Characterization of a Histidine-Containing Tetrapeptide Crystallized with Copper Chloride. [PDF]

ACS Omega
Nishiyama Y, Dimo VS, Motai K, Wada Y, Kawano M, Hayamizu Y.   +5 more
europepmc   +1 more source

Human Schlafen 14 Cleavage of Short Double‐Stranded RNAs Underpins its Antiviral Activity

Advanced Science, EarlyView.
SLFN14 is associated with human diseases. SLFN14 is found to cleave RNAs containing short duplexes. The cryo‐EM structures of SLFN14 and SLFN14‐hairpin RNA complex reveal that SLFN14 assembles into a ring‐like dimer; two RNase domains form an RNA‐binding groove accommodating a hairpin RNA.
Mengyun Li, Dapeng Sun, Wei Hao, Hua Fu, Yueli Zhang, Zhijian Li, Bo Qin, Yumei Wang, Sheng Cui   +8 more
wiley   +1 more source

Proton and Metal Dication Affinities of Tetracyclic Imidazo[4,5-<i>b</i>]Pyridine-Based Molecules: Insights from Mass Spectrometry and DFT Analysis. [PDF]

Molecules
Vrban L, Martinac IA, Hranjec M, Pocrnić M, Galić N, Kobetić R, Vianello R.   +6 more
europepmc   +1 more source

BIOLOGICAL ACTIVITY OF DIAZONIUM COMPOUNDS (II): POSITIVE INO- AND CHRONOTROPIC ACTIONS ON GUINEA PIG ATRIA OF 4 (OR 5)-DIAZO-IMIDAZOLE-5 (OR 4)-CARBOXAMIDE

, 1968
HEITAROH IWATAJ, Itaru Yamamoto, Makoto Oka   +2 more
openalex   +1 more source

Imidazole Catalyses in Aqueous Systems. III. Formation of the Catalyst-Substrate Complex in the Hydrolysis of a Phenyl Ester Catalyzed by a Naphthylimidazole Derivative [PDF]

, 1970
Toyoki Kunitake, Seiji Shinkai, Chuji Aso   +2 more
openalex   +1 more source

Hydrogen‐Producing Catalysts Based on Ferredoxin Scaffolds

Advanced Science, EarlyView.
Selected plant‐type ferredoxins that lack their natural [2Fe‐2S] clusters functionally bind a hydrogenase active site cofactor and act as hydrogenases themselves. In combination with photosystem I, the light‐dependent H₂ evolution almost matches the H₂ production rates of the natural system.
Yiting She, Vera Engelbrecht, Jacek Kozuch, Ulf‐Peter Apfel, Sven T. Stripp, Anja Hemschemeier, Thomas Happe   +6 more
wiley   +1 more source

<i>N</i>-Heterocyclic Olefins of Pyrazole and Indazole. [PDF]

Org Lett
Zhu B, Woyciechowski R, Hübner EG, Lederle F, Schmidt A.   +4 more
europepmc   +1 more source

Reactivity of Peptide Imidazole, Amino, and Phenolic Groups towards p-Nitrophenyl Acetate

, 1963
Walter L. Koltun, Lionel Ng, Frank R.N. Gurd   +2 more
openalex   +1 more source