Results 51 to 60 of about 4,157 (168)
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Advanced Science, Volume 13, Issue 20, 9 April 2026.Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
Imidazoles and imidazole metabolism
, 1966 Thesis submitted for the degree of Doctor of Philosophy at the University of the Witwatersrand, Johannesburg, South Africa.Only a small number of compounds containing the imidazole ring are found in living systems, but most of these possess marked ...
Trout, G. E.
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Separator Engineering for Stable Zinc Anodes in Aqueous Zinc‐Ion Batteries
Batteries &Supercaps, Volume 9, Issue 4, April 2026.Aqueous Zinc‐ion batteries boast high energy density, low cost, and safety but face challenges like zinc dendrites, hydrogen evolution reaction, and anode corrosion. Separator engineering—modifying glass fiber separators and developing novel ones—addresses these issues, boosting their electrochemical performance and long‐cycle stability.
Xiao Huang +8 more
wiley +1 more source
ChemistryEurope, Volume 4, Issue 4, April 2026.Cathepsin B‐sensitive peptide–adjuvant conjugates are designed, synthesized, and evaluated to deliver an antigenic peptid and an adjuvant targeting Toll‐like receptors 7 and 8 (TLR7/8) to antigen presenting cells. The adjuvant is released by cathepsin B resulting in antigen presentation and TLR mediated T cell activation.
Marjolein M. E. Isendoorn +6 more
wiley +1 more source
Cancer Nexus, Volume 2, Issue 2, April 2026.ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han +5 more
wiley +1 more source
Vibrational study of the copper(II)-carcinine complexes and tautomerism of imidazole side chain.
, 2006 Carcinine (p-alanyl-histamine) is a naturai imidazole-containing compound found in the non-protein fraction of mammalian tissues, probably involved in the carnosine-histidine-histamine metabolic pathway and in the mammalian physiologic response to stress.
TINTI, ANNA +2 more
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The peptidase neurolysin (Nln) has been validated as a potential target for developing therapeutics for ischemic stroke (IS). Overexpression of Nln in a mouse model of IS provides significant cerebroprotection, leading to reduced infarction size and ...
Vardan T. Karamyan (2319286) +9 more
core +1 more source
Ternary complexes of Cu(II) involving histidine and another amino acid or dipeptide [PDF]
, 1990 577-580The stability constants of ternary complexes of the type (CuLA) where A= histidine; and L= glycylglycine (L1), glycyl--alanine(L2), glycyl--leucine(L3), tryptophan (L4), phenylalanine (L5), tyrosine (L6) or 3,4-dihydroxyphenylalanine (L-dopa) (L7)
Manjula, V +2 more
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Crystal structure and conformation of the cyclic dipeptide cyclo-(L-histidyl-L-aspartyl) trihydrate
, 1978 The crystal structure of cyclo-(L-histidyl-L-aspartyl) trihydrate has been determined by X-ray diffraction techniques are refined to a final R index of 0.056 for 1601 reflections.
Venkatesan, K., Ramani, R., Marsh, R. E.
core +2 more sources
Dipeptide catalysed prebiotic polymerization of RNA
, 2011 A very short peptide composed of only two amino acid residues; Ser and His, was reported to exhibit broad hydrolytic activities. The dipeptide SerHis can catalyse the hydrolysis of esters, proteins and nucleic acids1.
Wieczorek, Rafal +2 more
core +1 more source