Results 91 to 100 of about 22,275 (301)
Interface Dynamics in Biomolecular Condensates by High‐Speed AFM
Advanced Materials Interfaces, EarlyView.High‐speed atomic force microscopy provides nanoscale structural dynamics at the liquid interface of biomolecular condensates, key elements in several cellular pathways. By addressing the challenges of low surface tension and condensate‐induced instabilities, we achieve nanometer spatial and sub‐second temporal resolution, revealing structural ...
Andreas Santamaria +6 more
wiley +1 more source
, 2015 A variety of 2-substituted 5-alkynyl-1H-imidazoles were easily prepared by a one-pot sequential procedure involving a highly regioselective electrophilic C-5 bromination of 1,2-dimethyl-1H-imidazole, 2-chloro-1-methyl-1H-imidazole, and 2-aryl-1-methyl-1H-
Giulia Marianetti +7 more
core +1 more source
Advanced Science, EarlyView.A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait +7 more
wiley +1 more source
Health Technology Assessment, 2018 Background: Several therapies have recently been approved for use in the NHS for pretreated advanced or metastatic renal cell carcinoma (amRCC), but there is a lack of comparative evidence to guide decisions between them.
Steve J Edwards +7 more
doaj +1 more source
Optical Behavior of Substituted 4‑(2′-Hydroxyphenyl)imidazoles
, 2016 A set of tetraarylimidazoles bearing a 2-hydroxyphenyl substituent at position 4, as well as their models lacking intramolecular hydrogen bonds, was efficiently synthesized.
Artur Jeżewski (1656550) +3 more
core +1 more source
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
Advanced Science, EarlyView.ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
An overview of structurally diversified anticonvulsant agents
Acta Pharmaceutica, 2019 There are several limited approaches to treat epilepsy in hospitals, for example, using medicines, surgery, electrical stimulation and dietary interventions.
Al-Otaibi Faisal
doaj +1 more source
Thermochemical properties of different 1-(R-phenyl)-1H-imidazoles [PDF]
, 2017 © 2016 Elsevier B.V.Phenyl substituted imidazoles exhibit versatile biological activity. 1-(R-phenyl)-1H-imidazoles with different functional groups R provide a convenient suitcase of molecules with tunable physicochemical properties adjustable for many ...
Kaliner M. +3 more
core
OH-Initiated Oxidation of Imidazoles in Tropospheric Aqueous-Phase Chemistry
, 2019 Imidazoles formed via the reaction of dicarbonyls with nitrogen containing compounds in the atmospheric particle phase can be expected to initiate secondary organic aerosol (SOA) growth due to their potential to act as photosensitizers.
Tamara Felber (6369281) +2 more
core +1 more source
, 2020 An efficient and novel electrochemical oxidative tandem cyclization of aryl ketones and benzylamines for the synthesis of 1,2,4-trisubstituted-(1H)-imidazoles has been developed under metal- and oxidant-free conditions.
Kun Liu +15 more
core +1 more source