Results 71 to 80 of about 16,360 (266)

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

open access: yesAdvanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim   +9 more
wiley   +1 more source

Synthesis of imidazole derivatives in the last 5 years: An update

open access: yesHeterocyclic Communications
Imidazole and its derivatives possess remarkable versatility, finding applications in medicine, synthetic chemistry, and industry. This review explores the latest advancements observed over the last few years (2018–2022), focusing on diverse ...
Devi Mayanglambam Maneeta   +3 more
doaj   +1 more source

Nuclear Quadrupole Resonance Spectroscopy: Tautomerism and Structure of Functional Azoles

open access: yesCrystals, 2019
The Nuclear Quadrupole Resonance spectroscopy data of functionalized azoles (imidazoles, triazoles and corresponding benzazoles) are reviewed and critically discussed. The possibility of studying the tautomerism of azoles by the NQR method is considered.
Lyudmila I. Larina
doaj   +1 more source

Interface Engineering via Sb2Te3 Deposition Enables High‐Performance SWCNT Film Thermoelectrics

open access: yesAdvanced Functional Materials, EarlyView.
SWCNTs are promising for flexible thermoelectrics but suffer from low performance. Here, cold‐pressed SWCNT films combined with deposited Sb2Te3 form engineered interfaces that enhance charge transport and energy filtering. The composite achieves a high power factor (25.82 µW cm−1 K−2) and delivers a power density of 3 mW cm−2 at ΔT = 40 K, with ...
Yuan‐Meng Liu   +11 more
wiley   +1 more source

Halide Perovskite Integrated Photovoltaic Cathodes Incorporating Pt on ZIF‐8‐Derived Carbon for Solar Hydrogen Production

open access: yesAdvanced Functional Materials, EarlyView.
A low‐Pt catalyst supported on zeolitic imidazolate framework (ZIF‐8)‐derived porous carbon and graphite is integrated with a halide perovskite photovoltaic, yielding cathodes that achieve a high photocurrent density (∼20 mA cm−2) under simulated sunlight and exhibit remarkable stability in acidic media over several days, thereby demonstrating a ...
Na Yeong Oh   +12 more
wiley   +1 more source

Axitinib, cabozantinib, everolimus, nivolumab, sunitinib and best supportive care in previously treated renal cell carcinoma: a systematic review and economic evaluation

open access: yesHealth Technology Assessment, 2018
Background: Several therapies have recently been approved for use in the NHS for pretreated advanced or metastatic renal cell carcinoma (amRCC), but there is a lack of comparative evidence to guide decisions between them.
Steve J Edwards   +7 more
doaj   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

An overview of structurally diversified anticonvulsant agents

open access: yesActa Pharmaceutica, 2019
There are several limited approaches to treat epilepsy in hospitals, for example, using medicines, surgery, electrical stimulation and dietary interventions.
Al-Otaibi Faisal
doaj   +1 more source

HOF‐Stabilized Apple EV Nanocargo in an NIR‐Responsive Hydrogel Enables On‐Demand Therapeutic Modulation for Transdermal Deep‐Joint Osteoarthritis Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
An NIR‐responsive transdermal hydrogel integrating apple EV nanocargo, berberine, piperine, HOFs, and graphene oxide enables localized osteoarthritis modulation. The platform supports enhanced transdermal delivery together with mild hyperthermia‐associated and redox‐related responses, leading to reduced inflammation and oxidative stress, improved ...
Yu‐Wen Tseng   +9 more
wiley   +1 more source

Affinity‐Tuned Albumin Hitchhiking Extends the Bioorthogonal Capture Window in Pretargeting Radiotheranostics

open access: yesAdvanced Healthcare Materials, EarlyView.
Pharmacokinetic engineering of clickable radioligands was achieved via albumin hitchhiking approach within a pretargeted radiotheranostics delivery platform. This approach reduced rapid renal elimination, expanded bioorthogonal capture window, boosted tumor uptake by ∼3.5‐fold, and improved the tumor‐to‐liver ratio by ∼6‐fold.
Xie He   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy