Results 51 to 60 of about 21,817 (300)
Acta Chimica Slovenica, 2022 In this study, NiCoFe2O4 nanoparticles were prepared and used as a reactive catalyst for the synthesis of trisubstituted imidazoles. The multicomponent reactions of aromatic aldehydes, benzil and ammonium acetate were carried out under solvent-free and ...
Leila Hemmesi, Hossein Naeimi
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Groups of antifungal drugs with role in animal health - Synthesis [PDF]
Medicamentul Veterinar, 2021 Fungal infections are an important part of infectious pathology, their incidence increasing considerably, as a result of the widespread use of antibiotics, corticosteroids, cytostatics and immunosuppressive drugs.
Răzvan F. Moruzi +6 more
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
(4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol
Molbank, 2023 (4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol was prepared through a five-step process starting from commercially available 1-acetyladamantane.
Ryan B. Gaynor +2 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Synthesis of imidazoles promoted by H3PW12O40-amino-functionalized CdFe12O19@SiO2 nanocomposite
Nanocomposites, 2020 H3PW12O40-amino-functionalized CdFe12O19@SiO2 nanocomposite has been applied as an effective nanocatalyst for the preparation of imidazoles by three-component reactions of benzil, ammonium acetate, and benzaldehydes under solvent-free condition ...
Javad Safaei-Ghomi +2 more
doaj +1 more source
Base-Promoted Annulation of Amidoximes with Alkynes: Simple Access to 2,4-Disubstituted Imidazoles
Molecules, 2020 An efficient construction of imidazole ring by a Cs2CO3-promoted annulation of amidoximes with terminal alkynes in DMSO has been developed. This protocol provides a simple synthetic route with high atom-utilization for the synthesis of 2,4-disubstituted ...
Hina Mehmood +3 more
doaj +1 more source
-imidazoles from α-methylene ketones
, 2018 A sequential one-pot approach to 2,4,5-trisubstituted imidazoles has been developed from α-methylene ketones and aldehydes. This methodology employs air-moisture stable reaction conditions and an inexpensive iodine/DMSO system affording a diverse range ...
Vineet Jeena +3 more
core +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source