Results 51 to 60 of about 30,850 (304)
Benzylic C–H Oxidation: Recent Advances and Applications in Heterocyclic Synthesis
MoleculesBenzylic C–H oxidation to form carbonyl compounds, such as ketones, is a fundamental transformation in organic synthesis as it allows for the preparation of versatile intermediates.
Nonhlelo Majola, Vineet Jeena
doaj +1 more source
Base-Promoted Annulation of Amidoximes with Alkynes: Simple Access to 2,4-Disubstituted Imidazoles
Molecules, 2020 An efficient construction of imidazole ring by a Cs2CO3-promoted annulation of amidoximes with terminal alkynes in DMSO has been developed. This protocol provides a simple synthetic route with high atom-utilization for the synthesis of 2,4-disubstituted ...
Hina Mehmood +3 more
doaj +1 more source
(4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol
Molbank, 2023 (4-(Adamantan-1-yl)-1-(isopropyl)-1H-imidazol-2-yl)methanol was prepared through a five-step process starting from commercially available 1-acetyladamantane.
Ryan B. Gaynor +2 more
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Sinteza i anthelmintičko djelovanje novih 2-supstituiranih-4,5-difenil imidazola [PDF]
, 2010 A series of 2-substituted-4,5-diphenyl imidazoles 1a-j were synthesized by refluxing benzil with different substituted aldehydes in the presence of ammonium acetate and glacial acetic acid.
C. Usifoh +13 more
core +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Synthesis of imidazoles promoted by H3PW12O40-amino-functionalized CdFe12O19@SiO2 nanocomposite
Nanocomposites, 2020 H3PW12O40-amino-functionalized CdFe12O19@SiO2 nanocomposite has been applied as an effective nanocatalyst for the preparation of imidazoles by three-component reactions of benzil, ammonium acetate, and benzaldehydes under solvent-free condition ...
Javad Safaei-Ghomi +2 more
doaj +1 more source
Synthesis, Spectral, Anticancer Studies on Cu (II) Complex of 2,4,5-Triphenyl-1H-Imidazole [PDF]
, 2016 Schiff bases of 2,4,5-triphenyl-1H-imidazole ligand and Cu(II) complex has been synthesized and characterized by 1H and 13C NMR, elemental analyses, molar conductance, thermal analysis (TGA), magnetic moment measurement, IR and UV-Vis.
Candrawati, I. (Iin) +2 more
core +3 more sources
Syntheses of polyalkylated imidazoles
Synthetic Communications, 2017 We have developed improved general simple methods for large-scale preparation of polyalkylated imidazoles by improved multicomponent synthesis from commercially available starting materials. A large range of NH- and N-alkyl-polyalkylimidazoles (40 in total, including novel compounds) has been synthesized.
Sigvart Evjen, Fiksdahl, Anne
openaire +1 more source
RSC Advances, 2021 The effect of heteroatoms on the structural and photophysical properties of donor-π-acceptor molecules, comprising imidazole and benzoxazolyl as well as imidazole and benzothiazolyl units, was investigated.
Hsing-Yu Chen +5 more
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source