Results 101 to 110 of about 30,622 (304)

Synthesis of imidazole derivatives in the last 5 years: An update

open access: yesHeterocyclic Communications
Imidazole and its derivatives possess remarkable versatility, finding applications in medicine, synthetic chemistry, and industry. This review explores the latest advancements observed over the last few years (2018–2022), focusing on diverse ...
Devi Mayanglambam Maneeta   +3 more
doaj   +1 more source

Nuclear Quadrupole Resonance Spectroscopy: Tautomerism and Structure of Functional Azoles

open access: yesCrystals, 2019
The Nuclear Quadrupole Resonance spectroscopy data of functionalized azoles (imidazoles, triazoles and corresponding benzazoles) are reviewed and critically discussed. The possibility of studying the tautomerism of azoles by the NQR method is considered.
Lyudmila I. Larina
doaj   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

open access: yesAdvanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang   +4 more
wiley   +1 more source

Engineered Protein‐Based Ionic Conductors for Sustainable Energy Storage Applications

open access: yesAdvanced Materials, EarlyView.
Rational incorporation of charged residues into an engineered, self‐assembling protein scaffold yields solid‐state protein films with outstanding ionic conductivity. Salt‐doping further enhances conductivity, an effect amplified in the engineered variants. These properties enable the material integration into an efficient supercapacitor.
Juan David Cortés‐Ossa   +14 more
wiley   +1 more source

Axitinib, cabozantinib, everolimus, nivolumab, sunitinib and best supportive care in previously treated renal cell carcinoma: a systematic review and economic evaluation

open access: yesHealth Technology Assessment, 2018
Background: Several therapies have recently been approved for use in the NHS for pretreated advanced or metastatic renal cell carcinoma (amRCC), but there is a lack of comparative evidence to guide decisions between them.
Steve J Edwards   +7 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

An overview of structurally diversified anticonvulsant agents

open access: yesActa Pharmaceutica, 2019
There are several limited approaches to treat epilepsy in hospitals, for example, using medicines, surgery, electrical stimulation and dietary interventions.
Al-Otaibi Faisal
doaj   +1 more source

Ammonium Salts as Curing Agents to Obtain Ionic Epoxy Resins With a Thermoplastic‐to‐Thermoset Transition

open access: yesAdvanced Materials, EarlyView.
Ionic epoxy networks are prepared using ammonium salts as hardeners, leading to a two‐stage curing process with a thermoplastic‐like intermediate. This uncommon behavior enables extrusion and fabrication of thermoplastic prepregs that can be cured into thermoset composites.
Izabela Kurowska   +10 more
wiley   +1 more source

General synthetic approach to 2-phenolic adenine derivatives [PDF]

open access: yes, 2012
A simple and general “one pot” procedure for the synthesis of 2,9-diarylpurines with one or multiple hydroxyl groups in the 2- aryl unit is described, from the reaction of 5-amino-4-amidinoimidazoles with phenolic aldehydes.National NMR Network, Fundação
Carvalho, M. Alice   +3 more
core   +1 more source

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