Results 31 to 40 of about 64,220 (327)

Asymmetric synthesis of γ-chloro-α,β-diamino- and β,γ-aziridino-α-aminoacylpyrrolidines and -piperidines via stereoselective Mannich-type additions of N-(diphenylmethylene)glycinamides across α-chloro-N-sulfinylimines [PDF]

, 2012
The asymmetric synthesis of new chiral gamma-chloro-alpha,beta-diaminocarboxylamide derivatives by highly diastereoselective Mannich-type reactions of N-(diphenylmethylene) glycinamides across chiral alpha-chloro-N-p-toluenesulfinylaldimines was ...
Augustyns, Koen, Callebaut, Gert, De Kimpe, Norbert, Mangelinckx, Sven, Tornroos, Karl W, Van der Veken, Pieter   +5 more
core   +3 more sources

Imine reductases (IREDs)

Current Opinion in Chemical Biology, 2017
Imine reductases (IREDs) have emerged as a valuable new set of biocatalysts for the asymmetric synthesis of optically active amines. The development of bioinformatics tools and searchable databases has led to the identification of a diverse range of new IRED biocatalysts that have been characterised and employed in different synthetic processes.
Mangas-Sanchez, Juan, France, Scott P, Montgomery, Sarah L, Aleku, Godwin A, Man, Henry, Sharma, Mahima, Ramsden, Jeremy I, Grogan, Gideon, Turner, Nicholas J   +8 more
openaire   +5 more sources

Hydrazones as Singular Reagents in Asymmetric Organocatalysis [PDF]

, 2016
This Minireview summarizes strategies and developments regarding the use of hydrazones as reagents in asymmetric organocatalysis, their distinct roles in nucleophile–electrophile, cycloaddition, and cyclization reactions.
Fernández Fernández, Rosario Fátima, Lassaletta, José M., Matador Martínez, Esteban, Monge Fernández, David, Retamosa Hernández, María Gracia   +4 more
core   +1 more source

Periselectivity in the Aza-Diels–Alder Reaction of 1-Azadienes with α-Oxoketenes: A Combined Experimental and Theoretical Study

Molecules, 2020
Inversions in the periselectivity of formal aza-Diels–Alder cycloadditions between α-oxoketenes generated by a thermally-induced Wolff rearrangement and 1-azadienes were observed experimentally as a function of the α-oxoketene and the 1-azadiene, as well
Marc Presset, Michel Rajzmann, Guillaume Dauvergne, Jean Rodriguez, Yoann Coquerel   +4 more
doaj   +1 more source

Transfer of electrophilic NH using convenient sources of ammonia: direct synthesis of N–H sulfoximines from sulfoxides [PDF]

, 2016
The transfer of nitrogen atoms is extremely valuable in the preparation of medicinal compounds. Here, a new system for NH transfer is developed to prepare sulfoximines, which are emerging as valuable motifs for drug discovery.
Bentley, Bizet, Bizet, Buglioni, Carroccia, Cheng, Collins, Collins, Collins, Dauban, Degennaro, Dohi, Dong, Fiori, Goldberg, Gutmann, Iacobucci, Ivanov, Jat, Johnson, Langner, Lücking, Lücking, Mancheño, Mendiola, Miao, Miyasaka, Ochiai, Okamura, Rit, Roizen, Romero, Shen, Silva, Souto, Starkov, Tamura, Teng, Wang, Weber, Williamson, Zenzola, Zhu, Zou   +43 more
core   +1 more source

Determination of Stability for imines derived from carbonyl compounds by conductivity measurements

Tikrit Journal of Pure Science, 2018
The project explained for the first time, how conductivity method was used in the determination of stability of some imines derived from mother compounds 2-acetyl pyridine, 3 or 4 –hydroxy benzaldehyde, and others. The method as found, simple precise
A.S.P. Azzouz, D.B.AL-Bakzo
doaj   +1 more source

Recent Advances in the Domino Annulation Reaction of Quinone Imines

Molecules
Quinone imines are important derivatives of quinones with a wide range of applications in organic synthesis and the pharmaceutical industry. The attack of nucleophilic reagents on quinone imines tends to lead to aromatization of the quinone skeleton ...
Zhen-Hua Wang, Xiao-Hui Fu, Qun Li, Yong You, Lei Yang, Jian-Qiang Zhao, Yan-Ping Zhang, Wei-Cheng Yuan   +7 more
doaj   +1 more source

Hybrid Organic−Inorganic Solids That Show Shape Selectivity [PDF]

, 2010
Hybrid organic−inorganic solids featuring millimolar/gram concentrations of intracrystalline organic moieties and shape-selectivity are synthesized. Pure-silica zeolite beta crystals are coated with zirconia and treated in aqueous sodium hydroxide to ...
Davis, Mark E., Moliner, Manuel, Román-Leshkov, Yuriy   +2 more
core   +1 more source

Synthesis and Reactions of New 4-Oxo-4H-benzopyran-3-carboxaldehydes Containing Hydroxy Groups or 2-Oxopyran Cycles

Molecules, 1998
The synthesis of eight hydroxy- and 2-oxopyranochromone-3-carboxaldehydes 3, 5 and their reactions with 2-hydroxyaniline, 2,4-dinitrophenylhydrazine and 2-benzothiazolylhydrazine were investigated.
Hafez M. El-Shaaer, Maria Matulova, Mikulas Furdik, Dusan Loos, Margita Lacova   +4 more
doaj   +1 more source

Ferrocene-derived P,N ligands : synthesis and application in enantioselective catalysis [PDF]

, 2013
Due to their unique steric and electronic properties, air-stability and modular structure, chiral hybrid P,N-ferrocenyl ligands play a prominent role in the field of asymmetric catalysis.
Noël, Timothy, Van der Eycken, Johan
core   +1 more source