Results 21 to 30 of about 28,814 (216)
Imiquimod induced vitiligo‐like lesions—A consequence of modified melanocyte function
Immunity, Inflammation and Disease, 2022 Introduction Imiquimod plays an important role in the management of condyloma and premalignant lesions. Successively, an increase of hypopigmented lesions following imiquimod application has been reported.
Haiyan Yu +4 more
doaj +1 more source
Chronic vulvar Paget’s disease: a therapeutic challenge with a review of the literature [PDF]
, 2019 Vulvar Paget’s disease is an uncommon adenocarcinoma of the female genital tract, occuring more often in postmenopausal Caucasian women and accounting for 1-2% of all vulvar malignancies. A 39-year-old female patient was examined for the erythematous and
Hatem, Bouzaiene +4 more
core +2 more sources
Systemic adverse events in imiquimod use for cervical intraepithelial neoplasia – A case series
Case Reports in Women's Health, 2019 Treatment for cervical intraepithelial neoplasia (CIN) often consists of an excisional procedure. However, less invasive treatment methods have been explored, such as topical treatment with imiquimod cream.
Tirza Wouters +8 more
doaj +1 more source
The Immunomodulatory Small Molecule Imiquimod Induces Apoptosis in Devil Facial Tumour Cell Lines. [PDF]
PLoS ONE, 2016 The survival of the Tasmanian devil (Sarcophilus harrisii) is threatened by devil facial tumour disease (DFTD). This transmissible cancer is usually fatal, and no successful treatments have been developed.
Amanda L Patchett +4 more
doaj +1 more source
Imiquimod cream improves photodamaged skin
Journal of Dermatology and Dermatologic Surgery, 2022 Chronic exposure to ultraviolet light causes wrinkles and dyspigmentation. Imiquimod cream is an immune-modulator medication approved for the treatment of genital warts, actinic keratosis, and superficial basal cell carcinoma.
Suliman S Alfaraj +2 more
doaj +1 more source
Acantholytic Pityriasis Rubra Pilaris Associated with Imiquimod 3.75% Application
Case Reports in Dermatological Medicine, 2011 Imiquimod is an immunomodulator with both antitumor and antiviral properties. It is currently available in two cream formulations as Aldara (imiquimod 5%) and the newly approved Zyclara (imiquimod 3.75%).
Natasha Atanaskova Mesinkovska +3 more
doaj +1 more source
Biology, 2021 The Toll-like receptor (TLR) 7 is a viral sensor for detecting single-stranded ribonucleic acid (ssRNA), the activation of which can induce intracellular innate immunity against viral infections.
Feng-Zhen Meng +6 more
doaj +1 more source
Effect of topical imiquimod as primary treatment for lentigo maligna: the LIMIT-1 study [PDF]
, 2016 Background: Topical imiquimod is sometimes used for lentigo maligna (LM) in situ melanoma instead of surgery, but frequency of cure is uncertain. Pathological complete regression (pCR) is a logical surrogate marker for cure after imiquimod, although ...
, NCRI Skin Cancer Clinical Studies Group, the U.K. Dermatology Cl +7 more
core +4 more sources
The systemic response to topical Aldara treatment is mediated through direct TLR7 stimulation as Imiquimod enters the circulation [PDF]
, 2017 Topical application of Aldara cream, containing the Toll-like receptor 7/8 agonist Imiquimod, is a widely used mouse model for investigating the pathogenesis of psoriasis. We have previously used this model to study the effects of peripheral inflammation
Cavanagh, Jonathan +3 more
core +1 more source
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2019 The assessment of drug permeation into/across the skin is traditionally accomplished using Franz diffusion cells with subsequent analysis by conventional chromatographic methods such as HPLC and more recently using advanced imaging techniques.
Mohammed Hussain Al-Mayahy +2 more
doaj +1 more source