Results 31 to 40 of about 28,814 (216)
Overview on topical 5-ALA photodynamic therapy use for non melanoma skin cancers [PDF]
, 2014 Ultraviolet radiation (UV) contributes to a variety of skin diseases including inflammation, degenerative aging, and cancer. Historically, humans have been exposed to UV radiation mainly through occupational exposure; recreational UV exposure, however ...
Bianchini, Daniela +7 more
core +3 more sources
Вопросы вирусологии, 2017 Background. Imiquimod is an imidazole derivative acting as an immunomodulator on the level of innate and adaptive immune system. Our objective was to evaluate the antiviral activity of generically reproduced imiquimod administered subcutaneously in mice ...
V. S. Smirnov, S. V. Petlenko
doaj +1 more source
Peripheral inflammation is associated with remote global gene expression changes in the brain [PDF]
, 2014 Background: Although the central nervous system (CNS) was once considered an immunologically privileged site, in recent years it has become increasingly evident that cross talk between the immune system and the CNS does occur. As a result, patients with
Cavanagh, Jonathan +3 more
core +2 more sources
Iraqi Journal of Pharmaceutical Sciences, 2023 Psoriasis is a chronic, inflammatory condition that primarily affects the skin, hair, and joints and is associated with significant humanistic and economic consequences. Psoriasis was induced in mice in this work using an imiquimod 5%
Raghad Abdulsalam Khaleel +1 more
doaj +1 more source
Dermoscopy and methyl aminolevulinate: A study for detection and evaluation of field cancerization [PDF]
, 2016 Actinic keratosis (AK) is a keratinocyte intraepidermal neoplasia UV light – induced that frequently appears in sun-exposed areas of the skin. Although historically AK was de fi ned as “ precancerous ” , actually it is considered as the ...
Anzalone, Alessia +9 more
core +1 more source
Immunomodulator loaded microneedle arrays for targeted intradermal drug delivery to skin tumors
Drug DeliveryTopical therapy with imiquimod in a cream [5% w/w imiquimod cream (Aldara™)] for the treatment of nodular basal cell carcinoma (BCC) currently results in low cure rates, attributed to low imiquimod permeation.
Akmal H. Sabri +10 more
doaj +1 more source
Clinical utility of ingenol mebutate in the management of actinic keratosis. Perspectives from clinical practice [PDF]
, 2018 Actinic keratoses (AKs) are epidermal cutaneous neoplasia observed predominantly in middle-aged and older subjects with mainly photo type I and photo type II on sun-exposed surfaces as a result of DNA damage.
Bernardini, Nicoletta +3 more
core +1 more source
Imiquimod Targets Toxoplasmosis Through Modulating Host Toll-Like Receptor-MyD88 Signaling
Frontiers in Immunology, 2021 Toxoplasma gondii is a prevalent parasite of medical and veterinary importance. Tachyzoïtes and bradyzoïtes are responsible for acute and chronic toxoplasmosis (AT and CT), respectively.
Maguy Hamie +6 more
doaj +1 more source
Exosome-delivered microRNAs promote IFN-α secretion by human plasmacytoid DCs via TLR7 [PDF]
, 2018 The excessive production of type I IFNs is a hallmark and a main pathogenic mechanism of many autoimmune diseases, including systemic lupus erythematosus (SLE).
Andreoli, Laura +9 more
core +1 more source
JPRAS Open, 2017 Topical Imiquimod is increasingly used in the treatment of lentigo maligna (LM) for patients not suitable or willing for surgery. It acts as an immune response modifier and is recommended for use with caution in patients with autoimmune disorders.
E.A. Whatling +2 more
doaj +1 more source