Results 221 to 230 of about 322,455 (262)
Some of the next articles are maybe not open access.
The Journal of Clinical Psychiatry, 2002
Antidepressant efficacy may be compromised by early discontinuation of treatment secondary to common, treatment-emergent side effects, including nausea, agitation, and somnolence. Paroxetine controlled-release (CR) was developed to improve general tolerability and, in particular, gastrointestinal tolerability.To determine the antidepressant efficacy ...
Robert N, Golden +4 more
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Antidepressant efficacy may be compromised by early discontinuation of treatment secondary to common, treatment-emergent side effects, including nausea, agitation, and somnolence. Paroxetine controlled-release (CR) was developed to improve general tolerability and, in particular, gastrointestinal tolerability.To determine the antidepressant efficacy ...
Robert N, Golden +4 more
openaire +2 more sources
Verapamil intoxication after substitution of immediate-release for extended-release verapamil
American Journal of Health-System Pharmacy, 2001Straightforward reports of unusual drug experiences are included in this section. While selected references may be cited, the purpose of a Drug Experience report is not to present an extensive review of the literature. A related section, Grand Rounds, includes papers that are well-documented patient case reports with a thorough review of the important ...
P, Laberge +3 more
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Biopharmaceutics & Drug Disposition, 1989
AbstractA crossover study in 18 subjects evaluated the plasma concentration–time profile of two different 20 mg sustained‐release (SR) methylphenidate (MPH) tablets administered before breakfast, compared to a 10 mg immediate‐release (IR) tablet administered before breakfast and again 5 h later, before lunch.
K S, Patrick +4 more
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AbstractA crossover study in 18 subjects evaluated the plasma concentration–time profile of two different 20 mg sustained‐release (SR) methylphenidate (MPH) tablets administered before breakfast, compared to a 10 mg immediate‐release (IR) tablet administered before breakfast and again 5 h later, before lunch.
K S, Patrick +4 more
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Quetiapine Extended-Release Versus Immediate-Release Formulation
The Journal of Clinical Psychiatry, 2008The pharmacokinetic and pharmacodynamic profile of the immediate-release (IR) formulation of quetiapine is characterized by a rapid peak in plasma level and striatal dopamine D(2) receptor occupancy, followed by a rapid decrease to baseline levels, necessitating the use of twice-daily dosing.
Mamo, D C +6 more
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Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2011
Study Objective. To compare the effects of paroxetine on the pharmacokinetics and pharmacodynamics of the immediate‐release (IR) and extended‐release (ER) formulations of metoprolol.Design. Prospective, randomized, open‐label, 3‐way crossover study.Setting. General clinical research center.Subjects.
Robert B, Parker, Judith E, Soberman
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Study Objective. To compare the effects of paroxetine on the pharmacokinetics and pharmacodynamics of the immediate‐release (IR) and extended‐release (ER) formulations of metoprolol.Design. Prospective, randomized, open‐label, 3‐way crossover study.Setting. General clinical research center.Subjects.
Robert B, Parker, Judith E, Soberman
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Clinical Therapeutics, 2003
Gepirone, a 5-HT(1A) receptor agonist, has been assessed for use in the treatment of anxiety and depressive disorders. Azapirones, including gepirone, act to maintain neurotransmission at 5-HT(1A) receptors.The aim of this article was to review the pharmacology and clinical data for gepirone extended-release (ER) and immediate-release (IR) formulations
Donald S, Robinson +2 more
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Gepirone, a 5-HT(1A) receptor agonist, has been assessed for use in the treatment of anxiety and depressive disorders. Azapirones, including gepirone, act to maintain neurotransmission at 5-HT(1A) receptors.The aim of this article was to review the pharmacology and clinical data for gepirone extended-release (ER) and immediate-release (IR) formulations
Donald S, Robinson +2 more
openaire +2 more sources
Zegerid--immediate-release omeprazole.
The Medical letter on drugs and therapeutics, 2005The FDA has approved marketing of Zegerid powder for oral suspension (Santarus), an immediate-release formulation of the proton-pump inhibitor (PPI) omeprazole (Prilosec, and others). All other oral PPIs are delayed-release, enteric-coated formulations designed to prevent degradation of the drug by gastric acid.
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An urgent call for the immediate release of Israeli hostages
The Lancet, 2023Shani, Paluch-Shimon +2 more
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Calling for an immediate release of captive children in Gaza
The Lancet, 2023Shani, Levany +2 more
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