Results 71 to 80 of about 2,811,674 (298)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Effect of Carnosine on Prooxidant–Antioxidant Balance in Several Tissues of Rats Exposed to Chronic Cold Plus Immobilization Stress

Journal of Pharmacological Sciences, 2012
In this study, we investigated the effect of l-carnosine (CAR) on prooxidant–antioxidant balance in several tissues of rats exposed to chronic stress. Both cold and immobilization stresses were applied to rats at the same time.
Esra Betül Kalaz, Betül Evran, Seval Develi-İş, Pervin Vural, Semra Doğru-Abbasoğlu, Müjdat Uysal   +5 more
doaj   +1 more source

The muscle proteome reflects changes in mitochondrial function, cellular stress and proteolysis after 14 days of unilateral lower limb immobilization in active young men.

PLoS ONE, 2022
Skeletal muscle unloading due to joint immobilization induces muscle atrophy, which has primarily been attributed to reductions in protein synthesis in humans.
Thomas M Doering, Jamie-Lee M Thompson, Boris P Budiono, Kristen L MacKenzie-Shalders, Thiri Zaw, Kevin J Ashton, Vernon G Coffey   +6 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Social disruption stress exacerbates alpha-galactosylceramide-induced hepatitis in mice [PDF]

, 2005
Objective: Psychosocial stress has been suggested as a possible aggravating factor in liver diseases, however, the underlying mechanism has yet to be clarified.
Chida, Y, Kubo, C, Sonoda, J, Sudo, N
core  

Patterns of biological effects of electromagnetic terahertz waves at frequencies of active cellular metabolites of post stressed changes in hemostasis

Russian Open Medical Journal, 2013
There had been studied the influence of electromagnetic waves at terahertz frequencies of active cellular metabolites (nitric oxide 150.176-150.664 GHz and 129.0 GHz atmospheric oxygen) on the changed parameters of homeostasis in experimental animals. It
Vyacheslav F. Kirichuk, Alexander A. Tsymbal   +1 more
doaj  

The effect of metformin on the motor activity and hippocampal dopamine metabolism in rats subjected to repeated immobilization stress

Pakistan Journal of Pharmaceutical Sciences
The present study investigates the impact of metformin treatment on motor activity and hippocampal dopamine metabolism in rats subjected to recurring immobilization stress.
Rushda Afroz, Huma Ikram, Shazia Nawaz, Nazish Mustafa, Tabinda Salman, Darakhshan Jabeen Haleem   +5 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Reno-protective effect of garlic extract against immobilization stress induced changes in rats

Asian Pacific Journal of Tropical Biomedicine, 2015
Objective: To examine immobilization stress-induced antioxidant defense alterations in rat kidney and the antioxidant effects of aqueous garlic extract in pre and post stress extract treatments.
Syed Kashif Zaidi, Shakeel Ahmed Ansari, Ghulam Md. Ashraf, Mohammad Alam Jafri, Shams Tabrez, Naheed Banu   +5 more
doaj   +1 more source