Results 1 to 10 of about 5,604 (216)

Immune-Mediated Necrotizing Myopathy: An Often Misdiagnosed Entity [PDF]

European Journal of Case Reports in Internal Medicine, 2015
Immune-mediated necrotizing myopathies (IMNM) are recognized as a subgroup of idiopathic inflammatory myopathies (IIM). IMNM are defined based on a combination of clinical presentation and laboratory studies, requiring a specific myopathological pattern ...
Joana Almeida Espírito Santo, Rui Garcia, Benilde Barbosa, Olinda Rebelo, José Pereira de Moura   +4 more
doaj   +8 more sources

Treatment of refractory immune-mediated necrotizing myopathy with efgartigimod [PDF]

Frontiers in Immunology
ObjectiveWe aimed to explore the efficacy and safety of efgartigimod in patients with refractory immune-mediated necrotizing myopathy (IMNM).MethodsThis open-label pilot observational study included seven patients with refractory IMNM, all of whom ...
MengTing Yang, JingChu Yuan, YiKang Wang, HongJun Hao, HongJun Hao, Wei Zhang, Wei Zhang, ZhaoXia Wang, ZhaoXia Wang, Yun Yuan, Yun Yuan, YaWen Zhao   +11 more
doaj   +5 more sources

Immune-Mediated Necrotizing Myopathy (IMNM): A Story of Antibodies [PDF]

Antibodies
Immune-mediated necrotizing myopathy (IMNM) is a rare and severe disease that corresponds to a specific entity of idiopathic inflammatory myopathy. Patients with IMNM suffer from proximal muscle weakness, and present high levels of creatine kinase and ...
Sarah Julien, Inès Challier, Marine Malleter, Fabienne Jouen, Laurent Drouot, Olivier Boyer   +5 more
doaj   +6 more sources

Pediatric immune-mediated necrotizing myopathy [PDF]

Frontiers in Neurology, 2023
Immune-mediated necrotizing myopathy (IMNM) is a type of inflammatory myopathy. Most patients with IMNM produce anti-3-hydroxy-3-methylglutaryl coenzyme A reductase or anti-signal-recognition particle autoantibodies.
Chen-Hua Wang, Chen-Hua Wang, Wen-Chen Liang, Wen-Chen Liang, Wen-Chen Liang   +4 more
doaj   +4 more sources

MRI patterns of thigh muscle involvement in immune-mediated necrotizing myopathy and dermatomyositis [PDF]

BMC Rheumatology
Background Immune-mediated necrotizing myopathy (IMNM) and dermatomyositis (DM) are characterized by weakness, hyperCKemia, associated autoantibodies, and varying extramuscular manifestations.
Anson W. Wilks, Kiana M. Vakil-Gilani, William D. Rooney, Dongseok Choi, Daniela Ghetie, Nizar Chahin   +5 more
doaj   +3 more sources

Tuberculosis-Induced Immune-Mediated Necrotizing Myopathy: A Challenging Case Scenario in a Non-Endemic Country [PDF]

Reports
Background and Clinical Significance: Tuberculosis (TB) poses a significant global health challenge; although low–middle income countries carry the heaviest burden, its diagnosis and treatment can be challenging in any country.
Agnese Colpani, Davide Astorri, Andrea De Vito, Giordano Madeddu, Sandro Panese, Nicholas Geremia   +5 more
doaj   +3 more sources

Clinical-pathologic classification of anti-HMGCR-positive immune-mediated necrotizing myopathy [PDF]

Scientific Reports
Anti-HMGCR-positive immune-mediated necrotizing myopathy (IMNM), also anti-HMGCR myopathy, was initially considered as an exclusively skeletal muscular disease, observed in elderly patients with an acute onset.
Yuyan Cao, Wei Li, Xiongjun He, Meiqi Liao, Kexin Hu, Shenghao Wu, Xin Zhang, Qianyi Liao, Ziqi Shen, Zhaoxin Liang, Chaoren Zheng, Zhuocheng Zhong, Haishan Jiang, Qin Huang, Hui Zheng   +14 more
doaj   +4 more sources

Beyond the Generalized Weakness: A Rare Case of Statin-Induced Immune-Mediated Necrotizing Myopathy [PDF]

Journal of Investigative Medicine High Impact Case Reports
Statin-induced immune-mediated necrotizing myopathy (IMNM) is a rare subtype of idiopathic inflammatory myopathy associated with statin exposure and characterized by positive anti-hydroxymethylglutaryl coenzyme A reductase antibodies. Here, we describe a
Leo Sakai DO, Hana Kazbour MD, James Huang MD   +2 more
doaj   +3 more sources

Prominent Asymmetric Muscle Weakness and Atrophy in Seronegative Immune-Mediated Necrotizing Myopathy [PDF]

Diagnostics, 2021
Immune-mediated necrotizing myopathy, a new subgroup of inflammatory myopathies, usually begins with subacute onset of symmetrical proximal muscle weakness.
Sunha Park, Dae-Hyun Jang, Jae-Min Kim, Nara Yoon   +3 more
doaj   +2 more sources

Anti-HMGCR positive immune-mediated necrotizing myopathy with associated neutrophilic urticarial dermatosis: A case report [PDF]

JAAD Case Reports
Kathleen M. Fletcher, MD, Nasro A. Isaq, MD, Julia S. Lehman, MD, Nessa Aghazadeh Mohandesi, MD   +3 more
doaj   +3 more sources