Results 1 to 10 of about 2,846 (189)
Treatment of refractory immune-mediated necrotizing myopathy with efgartigimod [PDF]
Frontiers in ImmunologyObjectiveWe aimed to explore the efficacy and safety of efgartigimod in patients with refractory immune-mediated necrotizing myopathy (IMNM).MethodsThis open-label pilot observational study included seven patients with refractory IMNM, all of whom ...
MengTing Yang +11 more
doaj +5 more sources
Immune-Mediated Necrotizing Myopathy (IMNM): A Story of Antibodies [PDF]
AntibodiesImmune-mediated necrotizing myopathy (IMNM) is a rare and severe disease that corresponds to a specific entity of idiopathic inflammatory myopathy. Patients with IMNM suffer from proximal muscle weakness, and present high levels of creatine kinase and ...
Sarah Julien +5 more
doaj +6 more sources
Pediatric immune-mediated necrotizing myopathy [PDF]
Frontiers in Neurology, 2023 Immune-mediated necrotizing myopathy (IMNM) is a type of inflammatory myopathy. Most patients with IMNM produce anti-3-hydroxy-3-methylglutaryl coenzyme A reductase or anti-signal-recognition particle autoantibodies.
Chen-Hua Wang +4 more
doaj +4 more sources
Immune-Mediated Necrotizing Myopathy: An Often Misdiagnosed Entity
European Journal of Case Reports in Internal Medicine, 2015 Immune-mediated necrotizing myopathies (IMNM) are recognized as a subgroup of idiopathic inflammatory myopathies (IIM). IMNM are defined based on a combination of clinical presentation and laboratory studies, requiring a specific myopathological pattern ...
Joana Almeida Espírito Santo +4 more
doaj +5 more sources
Immune-mediated necrotizing myopathy: Report of two cases. [PDF]
World J Clin Cases, 2023 Immune-mediated necrotizing myopathy is a rare autoimmune myopathy characterized by muscle weakness and elevated serum creatine kinase, with unique skeletal muscle pathology and magnetic resonance imaging features.In this paper, two patients are reported: One was positive for anti-signal recognition particle antibody, and the other was positive for ...
Chen BH, Zhu XM, Xie L, Hu HQ.
europepmc +4 more sources
Seronegative Immune-Mediated Necrotizing Myopathy: A Case Report. [PDF]
Cureus, 2022 Idiopathic inflammatory myopathies (IIMs) are a group of chronic autoimmune disorders characterized by proximal skeletal muscle weakness. One subtype of the IIMs is immune-mediated necrotizing myopathy (IMNM). IMNM can be further classified according to its autoantibody presence, including anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR ...
Patel S, Abu-Abaa M, Mousavi F.
europepmc +5 more sources
Characteristics of cardiac involvement in immune-mediated necrotizing myopathy [PDF]
Frontiers in Immunology, 2023 ObjectiveTo investigate the characteristics of cardiac involvement due to Immune-mediated Necrotizing Myopathy (IMNM).MethodsPatients diagnosed with Immune-mediated Necrotizing Myopathy (IMNM) who attended the Department of Neurology and the Department ...
Mengyang Liu +5 more
doaj +4 more sources
Tuberculosis-Induced Immune-Mediated Necrotizing Myopathy: A Challenging Case Scenario in a Non-Endemic Country [PDF]
ReportsBackground and Clinical Significance: Tuberculosis (TB) poses a significant global health challenge; although low–middle income countries carry the heaviest burden, its diagnosis and treatment can be challenging in any country.
Agnese Colpani +5 more
doaj +3 more sources
Statins and Immune-Mediated Necrotizing Myopathy
Clinical Management Issues, 2018 Statins are a well-recognized cause of a variety of skeletal myopathic effects, which generally resolve when discontinuing the treatment. Among autoimmune manifestations associated with statins, there is immune-mediated necrotizing myopathy (IMNM).
Mauro Turrin
doaj +5 more sources
MRI patterns of thigh muscle involvement in immune-mediated necrotizing myopathy and dermatomyositis [PDF]
BMC RheumatologyBackground Immune-mediated necrotizing myopathy (IMNM) and dermatomyositis (DM) are characterized by weakness, hyperCKemia, associated autoantibodies, and varying extramuscular manifestations.
Anson W. Wilks +5 more
doaj +3 more sources