Characteristics of cardiac involvement in immune-mediated necrotizing myopathy [PDF]
Frontiers in Immunology, 2023 ObjectiveTo investigate the characteristics of cardiac involvement due to Immune-mediated Necrotizing Myopathy (IMNM).MethodsPatients diagnosed with Immune-mediated Necrotizing Myopathy (IMNM) who attended the Department of Neurology and the Department ...
Mengyang Liu +5 more
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Immune-mediated necrotizing myopathy: Report of two cases. [PDF]
World J Clin Cases, 2023 Immune-mediated necrotizing myopathy is a rare autoimmune myopathy characterized by muscle weakness and elevated serum creatine kinase, with unique skeletal muscle pathology and magnetic resonance imaging features.In this paper, two patients are reported: One was positive for anti-signal recognition particle antibody, and the other was positive for ...
Chen BH, Zhu XM, Xie L, Hu HQ.
europepmc +4 more sources
Seronegative Immune-Mediated Necrotizing Myopathy: A Case Report. [PDF]
Cureus, 2022 Idiopathic inflammatory myopathies (IIMs) are a group of chronic autoimmune disorders characterized by proximal skeletal muscle weakness. One subtype of the IIMs is immune-mediated necrotizing myopathy (IMNM). IMNM can be further classified according to its autoantibody presence, including anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR ...
Patel S, Abu-Abaa M, Mousavi F.
europepmc +5 more sources
Statins and Immune-Mediated Necrotizing Myopathy
Clinical Management Issues, 2018 Statins are a well-recognized cause of a variety of skeletal myopathic effects, which generally resolve when discontinuing the treatment. Among autoimmune manifestations associated with statins, there is immune-mediated necrotizing myopathy (IMNM).
Mauro Turrin
doaj +3 more sources
An odd case of immune-mediated necrotizing myopathy, complicated with sagittal, transverse and sigmoid sinus thrombosis [PDF]
Balneo and PRM Research Journal, 2023 INTRODUCTION: Immune-mediated necrotizing myopathy (IMNM) is a rare variant of immune-mediated inflammatory myopathy (IMIM) that exhibits a severe prognosis and is unresponsive to conventional treatment.
Andreea Trandafir +3 more
doaj +2 more sources
Immune-Mediated Necrotizing Myopathy Associated With Myelodysplastic Syndrome
Annals of Internal Medicine: Clinical Cases, 2023 Autoimmune diseases can often be diagnosed in patients with myelodysplastic syndrome (MDS). Here, we review the emerging literature linking MDS and rare presentations of autoimmunity, including myositis.
Katherine M. Sheu +3 more
doaj +2 more sources
Immune-Mediated Necrotizing Myopathy Manifesting after Five Years of Statin Therapy [PDF]
Case Reports in Rheumatology, 2023 Immune-mediated necrotizing myopathy (IMNM) is an increasingly common and serious condition in which autoantibodies attack muscle fibers causing clinically significant muscle weakness, fatigue, and myalgias.
Nathan G. DeRon +3 more
doaj +2 more sources
Two Cases of Statin-Induced Immune-Mediated Necrotizing Myopathy: A Rare Side Effect of Statins
RheumatoStatins are effective drugs for lowering cholesterol and reducing cardiovascular risk. Rarely, they can trigger autoimmune myopathies like immune-mediated necrotizing myopathy (IMNM), associated with anti-HMGCR antibodies.
Luis Angel Montero Furelos +2 more
doaj +3 more sources
An atorvastatin‐induced positive anti‐HMGCR immune‐mediated necrotizing myopathy case [PDF]
Clinical Case ReportsKey Clinical Message Statins can commonly cause myopathy. Most of the time, stopping the culprit drug should solve the problem. However, if the drug has been discontinued but muscle weakness continues to worsen, immune‐mediated myopathy should be taken ...
Nattanicha Chaisrimaneepan +3 more
doaj +2 more sources
Rheumatoid Arthritis Associated With Anti-Signal Recognition Particle Immune-Mediated Necrotizing Myopathy: A Case Report [PDF]
Journal of Investigative Medicine High Impact Case ReportsImmune-mediated necrotizing myopathy (IMNM) is a rare subtype of idiopathic inflammatory myopathy that is characterized by severe subacute proximal weakness, myofiber necrosis, and significantly elevated serum creatine kinase.
Mohamed Reda Belkhribchia MD +6 more
doaj +2 more sources