Beyond the Generalized Weakness: A Rare Case of Statin-Induced Immune-Mediated Necrotizing Myopathy [PDF]
Journal of Investigative Medicine High Impact Case ReportsStatin-induced immune-mediated necrotizing myopathy (IMNM) is a rare subtype of idiopathic inflammatory myopathy associated with statin exposure and characterized by positive anti-hydroxymethylglutaryl coenzyme A reductase antibodies. Here, we describe a
Leo Sakai DO +2 more
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Prominent Asymmetric Muscle Weakness and Atrophy in Seronegative Immune-Mediated Necrotizing Myopathy [PDF]
Diagnostics, 2021 Immune-mediated necrotizing myopathy, a new subgroup of inflammatory myopathies, usually begins with subacute onset of symmetrical proximal muscle weakness.
Sunha Park +3 more
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Anti-HMGCR positive immune-mediated necrotizing myopathy with associated neutrophilic urticarial dermatosis: A case report [PDF]
JAAD Case ReportsKathleen M. Fletcher, MD +3 more
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An odd case of immune-mediated necrotizing myopathy, complicated with sagittal, transverse and sigmoid sinus thrombosis [PDF]
Balneo and PRM Research Journal, 2023 INTRODUCTION: Immune-mediated necrotizing myopathy (IMNM) is a rare variant of immune-mediated inflammatory myopathy (IMIM) that exhibits a severe prognosis and is unresponsive to conventional treatment.
Andreea Trandafir +3 more
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Immune-Mediated Necrotizing Myopathy [PDF]
Current Rheumatology Reports, 2018 Immune-mediated necrotizing myopathy (IMNM) is a type of autoimmune myopathy characterized by relatively severe proximal weakness, myofiber necrosis with minimal inflammatory cell infiltrate on muscle biopsy, and infrequent extra-muscular involvement. Here, we will review the characteristics of patients with IMNM.Anti-signal recognition particle (SRP ...
Iago Pinal‐Fernandez +2 more
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Immune-Mediated Necrotizing Myopathy Associated With Myelodysplastic Syndrome
Annals of Internal Medicine: Clinical Cases, 2023 Autoimmune diseases can often be diagnosed in patients with myelodysplastic syndrome (MDS). Here, we review the emerging literature linking MDS and rare presentations of autoimmunity, including myositis.
Katherine M. Sheu +3 more
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Immune-Mediated Necrotizing Myopathy Manifesting after Five Years of Statin Therapy [PDF]
Case Reports in Rheumatology, 2023 Immune-mediated necrotizing myopathy (IMNM) is an increasingly common and serious condition in which autoantibodies attack muscle fibers causing clinically significant muscle weakness, fatigue, and myalgias.
Nathan G. DeRon +3 more
doaj +2 more sources
Leflunomide-Induced Immune-Mediated Necrotizing Myopathy in a Patient With Rheumatoid Arthritis: A Case Report [PDF]
Journal of Investigative Medicine High Impact Case Reports, 2023 Immune-mediated necrotizing myopathy (IMNM) is a subtype of inflammatory myopathy that is characterized by proximal muscle weakness, markedly elevated serum creatine kinase, myopathic electromyographic findings, and muscle biopsies revealing necrosis or ...
Dylan Matthew Salazar BS +5 more
doaj +2 more sources
Two Cases of Statin-Induced Immune-Mediated Necrotizing Myopathy: A Rare Side Effect of Statins
RheumatoStatins are effective drugs for lowering cholesterol and reducing cardiovascular risk. Rarely, they can trigger autoimmune myopathies like immune-mediated necrotizing myopathy (IMNM), associated with anti-HMGCR antibodies.
Luis Angel Montero Furelos +2 more
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An atorvastatin‐induced positive anti‐HMGCR immune‐mediated necrotizing myopathy case [PDF]
Clinical Case ReportsKey Clinical Message Statins can commonly cause myopathy. Most of the time, stopping the culprit drug should solve the problem. However, if the drug has been discontinued but muscle weakness continues to worsen, immune‐mediated myopathy should be taken ...
Nattanicha Chaisrimaneepan +3 more
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