Results 11 to 20 of about 6,308 (185)

Treatment of Immune-Mediated Necrotizing Myopathy [PDF]

Curr Treatm Opt Rheumatol, 2023
Ogbonnaya-Whittlesey S, Kobrin D, Casal-Dominguez M, Mammen A, Pinal-Fernandez I.   +4 more
europepmc   +5 more sources

Pediatric immune-mediated necrotizing myopathy. [PDF]

Front Neurol, 2023
Immune-mediated necrotizing myopathy (IMNM) is a type of inflammatory myopathy. Most patients with IMNM produce anti-3-hydroxy-3-methylglutaryl coenzyme A reductase or anti-signal-recognition particle autoantibodies. IMNM is much rarer in children than in adults.
Wang CH, Liang WC.
europepmc   +4 more sources

The incidence of anti-HMGCR immune-mediated necrotizing myopathy: an Australian and UK retrospective multi-site cohort study. [PDF]

Rheumatology (Oxford)
Objectives Immune-mediated necrotizing myopathy (IMNM) with autoantibodies targeting 3-hydroxy-3-methylglutaryl-CoA reductase (anti-HMGCR) is considered a rare complication of statin therapy.
Khoo T, Tan E, Limaye V, Gunawardena H, Sadler R, Lamb JA, Lyu X, Brusch A, Needham M, Austin K, Bahadori A, Buch MH, Tomaszewski M, Lilleker JB, Chinoy H.   +14 more
europepmc   +2 more sources

MRI patterns of thigh muscle involvement in immune-mediated necrotizing myopathy and dermatomyositis. [PDF]

BMC Rheumatol
Immune-mediated necrotizing myopathy (IMNM) and dermatomyositis (DM) are characterized by weakness, hyperCKemia, associated autoantibodies, and varying extramuscular manifestations.
Wilks AW, Vakil-Gilani KM, Rooney WD, Choi D, Ghetie D, Chahin N.   +5 more
europepmc   +2 more sources

Immune-Mediated Necrotizing Myopathy: A Systematic Review of Antibody-Specific Mechanisms and Treatment Outcomes. [PDF]

Cureus
Immune-mediated necrotizing myopathy (IMNM) is a rare, antibody-defined subset of idiopathic inflammatory myopathies characterized by rapidly progressive proximal muscle weakness, markedly elevated creatine kinase (CK) levels, and myofiber necrosis with ...
Vaezi Z, Amini A.
europepmc   +2 more sources

Trends in Reports of Statin-Associated Immune-Mediated Necrotizing Myopathy Using the Japanese Adverse Drug Event Report Database. [PDF]

Drugs Real World Outcomes
In October 2016, precautions of the package inserts for ethical drugs containing statins were revised for immune-mediated necrotizing myopathy (IMNM). Our objective was to assess the trend in statin-associated IMNM reported before and after the release ...
Takami A, Terashima G, Tajima T, Yamashita K, Igarashi A.   +4 more
europepmc   +2 more sources

The clinical value of lymphocyte percentages and the monocyte-to-lymphocyte ratio in differentiating immune-mediated necrotizing myopathy from dermatomyositis. [PDF]

Front Neurol
Objective Immune-mediated necrotizing myopathy (IMNM) and dermatomyositis (DM) represent distinct subtypes of idiopathic inflammatory myopathies (IIMs).
Ma X, Huo K, Gao H, Ge H.
europepmc   +2 more sources

Identification of clinical subgroups in anti-SRP positive immune-mediated necrotizing myopathy patients using cluster analysis. [PDF]

Ther Adv Musculoskelet Dis
Background: Anti-signal recognition particle immune-mediated necrotizing myopathy (anti-SRP IMNM) is a rare autoimmune disorder characterized by muscle weakness and necrosis.
Cui B, Liu H, Liu R, Yin G, Xie Q.
europepmc   +2 more sources

A Case of Anti-3-Hydroxy-Methylglutaryl-Coenzyme a Reductase (Anti-HMGCR) Immune-Mediated Necrotizing Myopathy. [PDF]

Cureus
Anti-3-hydroxy-methylglutaryl-coenzyme A reductase (Anti-HMGCR) immune-mediated necrotizing myopathy (INMN) is a type of autoimmune myopathy that is commonly associated with a history of statin use.
George JS, Sabharwal S, Donnell R, Boral BM.   +3 more
europepmc   +2 more sources

Seronegative Immune-Mediated Necrotizing Myopathy: A Case Report. [PDF]

Cureus, 2022
Idiopathic inflammatory myopathies (IIMs) are a group of chronic autoimmune disorders characterized by proximal skeletal muscle weakness. One subtype of the IIMs is immune-mediated necrotizing myopathy (IMNM). IMNM can be further classified according to its autoantibody presence, including anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR ...
Patel S, Abu-Abaa M, Mousavi F.
europepmc   +3 more sources