Results 41 to 50 of about 2,846 (189)
Peculiar clinicopathological features of immune-mediated necrotizing myopathies [PDF]
Current Opinion in Rheumatology, 2018 Purpose of reviewIn the past decade, immune-mediated necrotizing myopathies have emerged as a separate entity in the heterogenous group of autoimmune myopathies. This group is characterized by clinical manifestations restricted to the muscle tissue, and until recently, the definition was based on muscular pathological features.Recent findingsIt was ...
Allenbach, Yves, Benveniste, Olivier
openaire +4 more sources
Inflammatory myopathies: an update for neurologists
Arquivos de Neuro-Psiquiatria, 2022 Idiopathic inflammatory myopathies (IIM) are a heterogenous group of treatable myopathies. Patients present mainly to the rheumatologist and neurologists, complaining of acute or subacute onset of proximal weakness. Extramuscular manifestations may occur,
André Macedo Serafim Silva +2 more
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Novel Presentation of Aphasia and Tremor in Immune-Mediated Necrotizing Myopathy [PDF]
Cureus, 2021 The authors present a unique case of immune-mediated necrotizing myopathy in a 60-year-old female who presented with aphasia, tremor, and progressive muscular weakness. To the best of our knowledge, the presentation of aphasia and tremor has not been previously reported in immune-mediated necrotizing myopathy. This rare presentation may mimic a variety
Gabriella Schmuter +1 more
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Journal of Clinical Rheumatology and Immunology, 2019 We report here a statin naive lady who had refractory myositis for years. The diagnosis was revised to be anti-HMGCR related immune mediated necrotizing myopathy after repeating the muscle biopsy and checking the autoantibody.
Lucas Luk, Ho So
doaj +1 more source
Diagnosis of Statin-Induced Necrotizing Myopathy: Contribution of Anti-HMGCR Antibodies
Acta Médica Portuguesa, 2022 Over the last few years, several cases of statin-induced necrotizing myopathy have been described. This myopathy is characterized by the necrosis of muscle fibers and the presence of anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR ...
Cláudia Fidalgo +3 more
doaj +1 more source
Immune Mediated Necrotizing Myopathy: A Rare Complication of Statin Therapy [PDF]
Clinics and Practice, 2020 Immune mediated necrotizing myopathy (IMNM) is part of the inflammatory myopathies group of diseases and presents with muscle weakness, myalgias and elevated serum creatine phosphokinase (CPK). Statin-induced IMNM is a rare complication. We present a patient with IMNM secondary to simvastatin use. The patient presented with proximal myopathy, dysphagia,
Prashanth Moku +9 more
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Rambam Maimonides Medical Journal, 2022 Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare systemic small-vessel disease, with heterogeneous clinical manifestations. While arthralgia and myalgia are common in the disease course, frank myositis is exceedingly rare.
Noa Hurvitz +6 more
doaj +1 more source
A Rare Case of Statin-induced Immune-mediated Necrotizing Myopathy [PDF]
Cureus, 2020 Statin-associated myopathy comprises of a spectrum of conditions ranging from benign myalgias to statin-induced immune-mediated necrotizing myopathy. Statin-induced immune-mediated necrotizing myopathy is an autoimmune condition wherein there is a destruction of normal skeletal muscular architecture that can be severely debilitating if not recognized ...
Anantha Sriharsha Madgula +3 more
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Dermatomyositis and Immune-Mediated Necrotizing Myopathies: A Window on Autoimmunity and Cancer [PDF]
Frontiers in Immunology, 2017 Autoimmune myopathies (myositides) are strongly associated with malignancy. The link between myositis and cancer, originally noticed by Bohan and Peter in their classification in 1975 (1), has been evidenced by large population-based cohort studies and a recent meta-analysis.
Olivier Boyer +3 more
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Statin-Induced Immune-Mediated Necrotizing Myopathy: An Increasingly Recognized Inflammatory Myopathy [PDF]
Cureus, 2020 Statin-induced immune-mediated necrotizing myopathy, also known as anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR) myopathy, is an inflammatory myopathy that is triggered by statin exposure and persists after statin discontinuation. It is a rare side effect of statins, distinct from the more commonly recognized statin-induced myalgia,
Oana P Stroie, Joshua Boster, Luke Surry
openaire +3 more sources