Results 61 to 70 of about 5,604 (216)

Aberrant Expression of High Mobility Group Box Protein 1 in the Idiopathic Inflammatory Myopathies

Frontiers in Cell and Developmental Biology, 2020
IntroductionHigh Mobility Group Box Protein 1 (HMGB1) is a DNA-binding protein that exerts inflammatory or pro-repair effects upon translocation from the nucleus.
Jessica Day, Jessica Day, Jessica Day, Sophia Otto, Sophia Otto, Kathy Cash, Preethi Eldi, Preethi Eldi, Pravin Hissaria, Pravin Hissaria, Susanna Proudman, Susanna Proudman, Vidya Limaye, Vidya Limaye, John D. Hayball, John D. Hayball, John D. Hayball   +16 more
doaj   +1 more source

The CHC22 Clathrin-GLUT4 Transport Pathway Contributes to Skeletal Muscle Regeneration [PDF]

, 2013
Mobilization of the GLUT4 glucose transporter from intracellular storage vesicles provides a mechanism for insulin-responsive glucose import into skeletal muscle.
Brodsky, Frances M., Camus, Stéphane M., Esk, Christopher, Funke, Birgit H., Griffin, Christine A., Hoshino, Sachiko, Ishii, Akiko, Kucherlapati, Raju, Margeta, Marta, Ohkoshi, Norio, Rando, Thomas A., Sakamoto, Kazuho, Tamaoka, Akira, Torres, Jorge A., Vassilopoulos, Stéphane   +14 more
core   +4 more sources

Myositis-specific autoantibodies, a cornerstone in immune-mediated necrotizing myopathy [PDF]

Autoimmunity Reviews, 2019
Over the past few years, myositis-specific autoantibodies played an increasing role in the inflammatory idiopathic myositis definition. They became the critical immunological marker for immune-mediated necrotizing myopathy diagnosis (IMNM) since the paradigm switch from histological to serological criteria. This review is focused on the key role of the
Olivier Boyer, Céline Anquetil, Olivier Benveniste, Yves Allenbach, Yves Allenbach, Nadège Wesner   +5 more
openaire   +4 more sources

Complete Recovery from COVID-19 Bilateral Pneumonia in an Immunosuppressed Man with Immune-Mediated Necrotizing Myopathy

Case Reports in Rheumatology, 2020
Immune-mediated necrotizing myopathy (IMNM) is a rare form of idiopathic immune myopathy (IIM) that requires immunotherapies, including immunosuppressive medications, if severe.
Thomas C. Bolig, Nada Abdulaziz, Elena Schiopu   +2 more
doaj   +1 more source

A common missense variant of LILRB₅ is associated with statin intolerance and myalgia [PDF]

, 2017
Aims A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) levels.
Abirami Veluchamy, Aleksi Tornio, Alex S F Doney, Alfirevic, Amend, Ana Alfirevic, Andrew D Morris, Anke-Hilse Maitland-van der Zee, Baigent, Banach, Bosch, Carithers, Chasman, Cho, Colin N A Palmer, Cyrielle Maroteau, Dam, Dan Carr, Daniel I Chasman, Donnelly, Draeger, Dube, Eleanor Dow, European Association for Cardiovascular Prevention & Rehabilitation, Ewan R Pearson, Fiona Carr, Fontenot, Graham, Gregoor, Helen M Colhoun, Hsia, Human genomics, Jacob George, Jacobson, Joint Formulary Committee, Katyrzyna Bloch, Kristjansson, Kuswanto, Lamperti, Lansberg, Law, Limaye, Maningat, McKinstry, Mia Wadelius, Mikus, Mohaupt, Moneeza K Siddiqui, Munir Pirmohamed, Neuvonen, Ngu-Uma Abelega, Nissen, O’Meara, Par Hallberg, Paul M Ridker, Qun-Ying Yue, R Development Core Team, Rannanheimo, Ridker, Rodriguez-Perea, Roger Tavendale, Sathasivam, Stroes, Stroes, Tornio, Viechtbauer, ÓNeill   +66 more
core   +3 more sources

Statin-associated necrotizing autoimmune myopathy with concurrent myasthenia gravis [PDF]

, 2021
Statin treatment has been associated with necrotizing autoimmune myopathy and has been linked to myasthenia gravis. We present an unprecedented clinical challenge with both disorders occurring in a patient treated with statins few months ...
Bertolasi, Laura, Caneve, Giorgio, Frasson, Emma, Monaco, Salvatore, Perelli, Anna, Piccinno, Maria Grazia, Ruzza, Giampietro, Simonetto, Marco, Vilotti, Cristina   +8 more
core   +1 more source

Leflunomide-Induced Immune-Mediated Necrotizing Myopathy in a Patient With Rheumatoid Arthritis: A Case Report

Journal of Investigative Medicine High Impact Case Reports, 2023
Immune-mediated necrotizing myopathy (IMNM) is a subtype of inflammatory myopathy that is characterized by proximal muscle weakness, markedly elevated serum creatine kinase, myopathic electromyographic findings, and muscle biopsies revealing necrosis or ...
Dylan Matthew Salazar BS, Devanshi Narendra Damani MD, Piya Kositangool BS, Melina Jo Ortiz BS, Jonathan Lavezo MD, Fatma Dihowm MD, MS   +5 more
doaj   +1 more source

Immune-mediated necrotizing myositis with hydroxy-3-methyl-glutaryl-coenzyme A reductase antibody positivity in MSA-negative and statin-naive profile

Indian Journal of Rheumatology, 2023
Statin-naïve immune-mediated necrotizing myopathy (IMNM) is a rare disease entity, the diagnosis of which is complicated in the absence of a reliable biomarker.
Kothapalli Nagamounika, Josna Joseph, R Hemanth Kumar, John Mathew   +3 more
doaj   +1 more source

Review Article : Neuromuscular causes of weakness in critically ill patients [PDF]

, 2017
Multiple predisposing factors are responsible for the development of neuromuscular weakness in a critically ill patient. Thorough history and physical examination is paramount and should not be omitted despite that the majority of patients are ...
Govindarajan, Raghav, Katyal, Nakul
core   +1 more source

Pharmacological management of dermatomyositis [PDF]

, 2018
K
Dankó, Katalin, Griger, Zoltán, Nagy-Vincze, Melinda   +2 more
core   +1 more source