Clinical Case Reports, Volume 13, Issue 11, November 2025.ABSTRACT Idiopathic inflammatory myopathy (IIM) encompasses rare autoimmune disorders causing muscle inflammation and weakness, with subtypes including dermatomyositis, necrotizing myopathy, antisynthetase syndrome, and inclusion body myositis. This case report details a 25‐year‐old South Asian male presenting with a 60‐day history of progressive ...
Ibrahim Khalil +3 more
wiley +1 more source
Chimeric Antigen Receptor T‐Cell Therapy and Autoimmune Diseases in the Nervous System
Immunity, Inflammation and Disease, Volume 13, Issue 11, November 2025.ABSTRACT Introduction Chimeric antigen receptor T‐cell (CAR‐T) therapy, a revolutionary immunotherapy originally developed for hematologic malignancies, has recently gained attention for its potential in treating autoimmune diseases. Increasing evidence suggests that CAR‐T cells can precisely target pathogenic immune populations, offering durable ...
Shun‐yu Yao +11 more
wiley +1 more source
The Role of C/EBP‐Homologous Protein in Idiopathic Inflammatory Myopathies
Journal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.ABSTRACT The Idiopathic Inflammatory Myopathies (IIMs) are a group of autoimmune disorders characterised by persistent muscle inflammation and diverse clinical manifestations. Common symptoms include muscle weakness, myalgia, and elevated serum creatine kinase levels. Recent findings highlight the relevance of muscle fibre necrosis in IIMs.
Monica Sciacco +9 more
wiley +1 more source
Dermatomyositis and Polymyositis: Are Both Ends of a Same Spectrum?
Journal of Cosmetic Dermatology, Volume 25, Issue 1, January 2026.
Yashdeep Singh Pathania
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Comprehensive transcriptomic analysis and machine learning reveal unique gene expression profiles in patients with immune‐mediated necrotizing myopathy [PDF]
, 2023 Hongjiang Liu +8 more
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Pathophysiological Mechanisms and Treatment of Dermatomyositis and Immune Mediated Necrotizing Myopathies: A Focused Review [PDF]
, 2022 Renske G Kamperman +4 more
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Immune-mediated necrotizing myopathy [PDF]
Neurologie pro praxi, 2017 Tomáš Kalous, Josef Zámečník
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Immune-mediated necrotizing myopathy due to statins exposure.
Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology, 2018 Statin-induced necrotizing autoimmune myopathy (IMNM) is an autoimmune disorder induced by anti-3-hydroxy-3-methylglutaryl-coenzyme-A reductase (anti-HMGCR) antibodies. We performed a retrospective clinical, histological, and radiological evaluation of 5 patients with a 3-year therapeutic follow-up.
Villa, Luisa +11 more
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Immune-Mediated Necrotizing Myopathy Initially Presenting as Erythema Nodosum.
Journal of inflammation research, 2020 Immune-mediated necrotizing myopathy (IMNM) is a type of autoimmune myopathy characterized by severe diffuse proximal myofiber necrosis in the context of inflammatory myopathy. Autoantibodies of anti-signal recognition particle and anti-hydroxy-3-methylglutaryl-CoA reductase are two antibodies specific to IMNM.
Ying,Shuni +8 more
openaire +4 more sources
Immune-mediated necrotizing myopathy: an important differential diagnosis of muscle weakness
, 2021 Camila Aguiar Lomônaco +4 more
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