Results 11 to 20 of about 1,650,706 (352)

Tumor-associated macrophages and Tregs influence and represent immune cell infiltration of muscle-invasive bladder cancer and predict prognosis

Journal of Translational Medicine, 2023
Introduction and objective Muscle-invasive urothelial bladder cancer (MIBC) is associated with limited response rates to systemic therapy, risk of recurrence and death.
Florestan J. Koll, S. Banek, L. Kluth, J. Köllermann, Katrin Bankov, F. Chun, P. Wild, A. Weigert, H. Reis   +8 more
semanticscholar   +1 more source

Role of Rip2 in development of tumor-infiltrating MDSCs and bladder cancer metastasis. [PDF]

, 2014
Tumor invasion and metastases represent a complex series of molecular events that portends a poor prognosis. The contribution of inflammatory pathways mediating this process is not well understood. Nod-like receptors (NLRs) of innate immunity function as
Chin, Arnold I, Zhang, Hanwei
core   +9 more sources

Landscape of Immune Microenvironment Under Immune Cell Infiltration Pattern in Breast Cancer

Frontiers in Immunology, 2021
Background Increasing evdence supports the suggestion that the immune cell infiltration (ICI) patterns play a pivotal role in tumor progression in breast cancer (BRCA).
Qianhui Xu, Shaohuai Chen, Yuanbo Hu, Wen Huang   +3 more
semanticscholar   +1 more source

CNS fibroblasts form a fibrotic scar in response to immune cell infiltration

Nature Neuroscience, 2021
Fibrosis is a common pathological response to inflammation in many peripheral tissues and can prevent tissue regeneration and repair. Here, we identified persistent fibrotic scarring in the CNS following immune cell infiltration in the experimental ...
Cayce E. Dorrier, D. Aran, Ezekiel Haenelt, Ryan N. Sheehy, K. K. Hoi, Lucija Pintarić, Yanan Chen, C. Lizama, K. Cautivo, Geoffrey A. Weiner, B. Popko, S. Fancy, Thomas D. Arnold, R. Daneman   +13 more
semanticscholar   +1 more source

Functional Blockade of E-Selectin in Tumor-Associated Vessels Enhances Anti-Tumor Effect of Doxorubicin in Breast Cancer [PDF]

, 2020
Chemotherapy is a mainstay of treatment for solid tumors. However, little is known about how therapy-induced immune cell infiltration may affect therapy response.
Chervoneva, Inna, Davis, Rachel, Gorenstein, David G, Hasan, Nafis, Hills, Natalie, Ichimura, Norihisa, Kameyama, Hiroyasu, Kondo, Yuji, Leslie, Macall, Lokesh, Ganesh L R, Morita, Yoshihiro, Rui, Hallgeir, Tanaka, Takemi, Volk, David E, Zhang, Roy   +14 more
core   +3 more sources

Identifying Immune Cell Infiltration and Effective Diagnostic Biomarkers in Rheumatoid Arthritis by Bioinformatics Analysis

Frontiers in Immunology, 2021
Background Rheumatoid arthritis (RA) is a chronic systemic autoimmune disorder characterized by inflammatory cell infiltration, leading to persistent synovitis and joint destruction. The pathogenesis of RA remains unclear.
Sheng Zhou, Hongcheng Lu, M. Xiong
semanticscholar   +1 more source

Identification and Verification of Immune-Related Gene Prognostic Signature Based on ssGSEA for Osteosarcoma

Frontiers in Oncology, 2020
Osteosarcoma is the most common malignant bone tumor in children and adolescence. Multiple immune-related genes have been reported in different cancers.
Bo Xiao, Bo Xiao, Liyan Liu, Liyan Liu, Aoyu Li, Aoyu Li, Cheng Xiang, Cheng Xiang, Pingxiao Wang, Pingxiao Wang, Hui Li, Hui Li, Tao Xiao, Tao Xiao   +13 more
doaj   +1 more source

Spatially variant immune infiltration scoring in human cancer tissues

npj Precision Oncology, 2022
The Immunoscore is a method to quantify the immune cell infiltration within cancers to predict the disease prognosis. Previous immune profiling approaches relied on limited immune markers to establish patients’ tumor immunity.
Mayar Allam, Thomas Hu, Jeongjin Lee, Jeffrey Aldrich, Sunil S. Badve, Yesim Gökmen-Polar, Manali Bhave, Suresh S. Ramalingam, Frank Schneider, Ahmet F. Coskun   +9 more
doaj   +1 more source

PNOC Expressed by B Cells in Cholangiocarcinoma Was Survival Related and LAIR2 Could Be a T Cell Exhaustion Biomarker in Tumor Microenvironment: Characterization of Immune Microenvironment Combining Single-Cell and Bulk Sequencing Technology

Frontiers in Immunology, 2021
BackgroundCholangiocarcinoma was a highly malignant liver cancer with poor prognosis, and immune infiltration status was considered an important factor in response to immunotherapy.
Zheng Chen, Mincheng Yu, Jiuliang Yan, Lei Guo, Bo Zhang, Shuang Liu, Jin Lei, Wentao Zhang, Binghai Zhou, Jie Gao, Zhangfu Yang, Xiaoqiang Li, Jian Zhou, Jia Fan, Qinghai Ye, Hui Li, Yongfeng Xu, Yongsheng Xiao   +17 more
doaj   +1 more source

Tumor Immunometabolism Characterization in Ovarian Cancer With Prognostic and Therapeutic Implications

Frontiers in Oncology, 2021
Metabolic dysregulation in the tumor microenvironment has significant impact on immune infiltration and immune responses. However, interaction between immunity and metabolism in the ovarian microenvironment requires further exploration. We constructed an
Miner Yang, Gaowen Chen, Kunjie Gao, Yifeng Wang   +3 more
doaj   +1 more source