Results 41 to 50 of about 1,693,225 (311)

The Prognostic Value of GNG7 in Colorectal Cancer and Its Relationship With Immune Infiltration

Frontiers in Genetics, 2022
Background: G Protein Subunit Gamma 7 (GNG7) is an important gene that regulates cell proliferation and induces apoptosis. However, the correlation between GNG7 expression and immune infiltration as well as patient prognosis of colorectal cancer (CRC ...
Can Fang, Rulei Zhong, Chenyang Qiu, Bing-bing Zou   +3 more
doaj   +1 more source

Peripheral Immune Cell Infiltration in the Hippocampus of Sepsis Mice. [PDF]

J Cell Mol Med
ABSTRACT Peripheral immune cell infiltration plays a key role in the excessive intracranial inflammatory response during sepsis, contributing to cognitive dysfunction and increased mortality. This study aims to elucidate the immune inflammatory status of hippocampal tissue in septic mice, providing potential ...
Zhang H, Zhang M, Gao Y, Chen Q, Liu Q, Meng F, Sun X, Fei M, Li C, Xiong L.   +9 more
europepmc   +4 more sources

Sp1 induced gene TIMP1 is related to immune cell infiltration in glioblastoma

Scientific Reports, 2022
Tumor immune microenvironment exerts a profound effect on the population of infiltrating immune cells. Tissue inhibitor of matrix metalloproteinase 1 (TIMP1) is frequently overexpressed in a variety of cells, particularly during inflammation and tissue ...
Lu Liu, Shuyao Yang, Ke-chen Lin, Xiao-Ran Yu, Jiaqi Meng, Chaolong Ma, Zheng Wu, Yuchao Hao, Ning Chen, Qi Ge, Wenli Gao, Xiang Wang, E. Lam, Lin Zhang, Fangcheng Li, Bilian Jin, D. Jin   +16 more
semanticscholar   +1 more source

The Role of Immune Escape and Immune Cell Infiltration in Breast Cancer [PDF]

Breast Care, 2018
While detailed analysis of aberrant cancer cell signaling pathways and changes in cancer cell DNA has dominated the field of breast cancer biology for years, there now exists increasing evidence that the tumor microenvironment (TME) including tumor-infiltrating immune cells support the growth and development of breast cancer and further facilitate ...
André, Steven, Barbara, Seliger
openaire   +2 more sources

Immune Characteristics in Biliary Atresia Based on Immune Genes and Immune Cell Infiltration

Frontiers in Pediatrics, 2022
BackgroundBiliary atresia (BA) is a serious biliary disease in infancy. Jaundice is the most visual and prominent symptom, and it mainly involves bile duct cells leading to the loss of intrahepatic and extrahepatic bile ducts. If left untreated, it will eventually progress to liver cirrhosis. The pathogenesis of BA is not clear, and it is now generally
Chenyu Yang, Chenyu Yang, Huiwu Xing, Huiwu Xing, Bingqian Tan, Bingqian Tan, Mingman Zhang, Mingman Zhang   +7 more
openaire   +3 more sources

A Transendothelial Leukocyte Transmigration Model Based on Computational Fluid Dynamics and BP Neural Network

Frontiers in Bioengineering and Biotechnology, 2022
The mechanism of immune infiltration involving immune cells is closely related to various diseases. A key issue in immune infiltration is the transendothelial transmigration of leukocytes.
Qingjia Chi, Zichang Yang, Hua-Ping Liang   +2 more
doaj   +1 more source

Genomic profiles and their associations with TMB, PD-L1 expression, and immune cell infiltration landscapes in synchronous multiple primary lung cancers

Journal for ImmunoTherapy of Cancer, 2021
Background Diagnosing and treating patients with multiple primary lung cancers (MPLCs) bring challenges to the clinic, and the preliminary evidence has revealed unsatisfying outcomes after targeted therapy and immunotherapy.
Chunhong Hu, Lishu Zhao, Wenliang Liu, S. Fan, Junqi Liu, Yuxuan Liu, Xiaohan Liu, Long Shu, Xianling Liu, Ping Liu, C. Deng, Zhenhua Qiu, Chen Chen, Yi Jiang, Qingchun Liang, Lingling Yang, Yang Shao, Qiongzhi He, Danlei Yu, Yue-yue Zeng, Yizheng Li, Yue Pan, Sujuan Zhang, Shenghao Shi, Yu Peng, Fang Wu   +25 more
semanticscholar   +1 more source

Profiling Tumor Infiltrating Immune Cells with CIBERSORT [PDF]

, 2018
Tumor infiltrating leukocytes (TILs) are an integral component of the tumor microenvironment and have been found to correlate with prognosis and response to therapy. Methods to enumerate immune subsets such as immunohistochemistry or flow cytometry suffer from limitations in phenotypic markers and can be challenging to practically implement and ...
Binbin, Chen, Michael S, Khodadoust, Chih Long, Liu, Aaron M, Newman, Ash A, Alizadeh   +4 more
openaire   +2 more sources

Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer [PDF]

British Journal of Cancer, 2013
The host immune reaction is represented by immune/inflammatory cell infiltrates. Here we systematically analysed tumour-infiltrating immune/inflammatory cells in pancreatic ductal carcinoma (PDC) and evaluated their clinicopathological impact.Using immunohistochemistry, we examined tumour-infiltrating CD68(+) pan-macrophages, HLA-DR(+)CD68(+) M1 ...
Ino, Y, Yamazaki-Itoh, R, Shimada, K, Iwasaki, M, Kosuge, T, Kanai, Y, Hiraoka, N   +6 more
openaire   +2 more sources

SERPINE1 associated with remodeling of the tumor microenvironment in colon cancer progression: a novel therapeutic target

BMC Cancer, 2021
Background The change of immune cell infiltration essentially influences the process of colorectal cancer development. The infiltration of immune cells can be regulated by a variety of genes.
Shaokun Wang, Li Pang, Zuolong Liu, Xiangwei Meng   +3 more
doaj   +1 more source