Results 41 to 50 of about 624,288 (309)

Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer [PDF]

British Journal of Cancer, 2013
The host immune reaction is represented by immune/inflammatory cell infiltrates. Here we systematically analysed tumour-infiltrating immune/inflammatory cells in pancreatic ductal carcinoma (PDC) and evaluated their clinicopathological impact.Using immunohistochemistry, we examined tumour-infiltrating CD68(+) pan-macrophages, HLA-DR(+)CD68(+) M1 ...
Ino, Y, Yamazaki-Itoh, R, Shimada, K, Iwasaki, M, Kosuge, T, Kanai, Y, Hiraoka, N   +6 more
openaire   +2 more sources

Immune signature of tumor infiltrating immune cells in renal cancer [PDF]

OncoImmunology, 2015
Tumor-associated immune cells have been discussed as an essential factor for the prediction of the outcome of tumor patients. Lymphocyte-specific genes are associated with a favorable prognosis in colorectal cancer but with poor survival in renal cell carcinoma (RCC).
Katharina, Geissler, Paolo, Fornara, Christine, Lautenschläger, Hans-Jürgen, Holzhausen, Barbara, Seliger, Dagmar, Riemann   +5 more
openaire   +2 more sources

A Transendothelial Leukocyte Transmigration Model Based on Computational Fluid Dynamics and BP Neural Network

Frontiers in Bioengineering and Biotechnology, 2022
The mechanism of immune infiltration involving immune cells is closely related to various diseases. A key issue in immune infiltration is the transendothelial transmigration of leukocytes.
Qingjia Chi, Zichang Yang, Hua-Ping Liang   +2 more
doaj   +1 more source

The tomato Prf complex is a molecular trap for bacterial effectors based on Pto transphosphorylation [PDF]

, 2013
The bacteria Pseudomonas syringae is a pathogen of many crop species and one of the model pathogens for studying plant and bacterial arms race coevolution.
A Balmuth, A Bendahmane, A Keller, A-J Wu, AI Nesvizhskii, Alexandra M. E. Jones, Alexi L. Balmuth, BJ DeYoung, BJ Deyoung, BP Thomma, CMT Rommens, F Shao, F Shao, FL Takken, G Sessa, HC McCann, J Ade, J Dong, J Zhou, JD Jones, Jeffery L. Dangl, John P. Rathjen, Jose R. Gutierrez, JP Rathjen, JR Gutierrez, KR Munkvold, L Shan, LN Johnson, M Bernoux, MR Swiderski, PN Dodds, R Cai, S Gimenez-Ibanez, SM Collier, T Boller, T Boller, T Maekawa, T Xiang, T Xiang, Tatiana S. Mucyn, TS Mucyn, TS Mucyn, V Bonardi, V Ntoukakis, Vardis Ntoukakis, VM Andriotis, W Xing, X Du   +47 more
core   +3 more sources

Impact of Human Immunodeficiency Virus in the Pathogenesis and Outcome of Patients with Glioblastoma Multiforme. [PDF]

, 2016
BackgroundImprovement in antiviral therapies have been accompanied by an increased frequency of non-Acquired Immune Deficiency Syndrome (AIDS) defining malignancies, such as glioblastoma multiforme.
Bui, Timothy T, Choy, Winward, Lagman, Carlito, Lee, Seung J, Safaee, Michael, Yang, Isaac   +5 more
core   +1 more source

Cancer Cell–Autonomous Parainflammation Mimics Immune Cell Infiltration [PDF]

Cancer Research, 2017
Abstract Parainflammation is a unique variant of inflammation, characterized by epithelial-autonomous activation of inflammatory response. Parainflammation has been shown to strongly promote mouse gut tumorigenesis upon p53 loss. In a recent study, we explored the prevalence of parainflammation in human cancer and determined its ...
Lasry, Audrey, Aran, Dvir, Butte, Atul J, Ben-Neriah, Yinon   +3 more
openaire   +4 more sources

Identification of testicular cancer immune infiltrates and novel immune cell subtypes

FEBS Open Bio, 2023
Testicular germ cell tumors (TGCT) are the most common type of testicular cancer, comprising 90–95% of cases and representing the most prevalent solid malignancy in young adult men. Immune infiltrates play important regulatory roles in tumors, but their role in TGCT remains unclear.
Zhiguo Zhu, Xujun Xuan, Xinkun Wang, Miaomiao Wang, Chunyang Meng, Zhonghai Li   +5 more
openaire   +3 more sources

RNF8 enhances the sensitivity of PD-L1 inhibitor against melanoma through ubiquitination of galectin-3 in stroma

Cell Death Discovery, 2023
The failure of melanoma immunotherapy can be mediated by immunosuppression in the tumor microenvironment (TME), and insufficient activation of effector T cells against the tumor.
Yanan Guo, Rong Shen, Keren Yang, Yutong Wang, Haoyun Song, Xiangwen Liu, Xin Cheng, Rile Wu, Yanfeng Song, Degui Wang   +9 more
doaj   +1 more source

Stromule extension along microtubules coordinated with actin-mediated anchoring guides perinuclear chloroplast movement during innate immunity. [PDF]

, 2018
Dynamic tubular extensions from chloroplasts called stromules have recently been shown to connect with nuclei and function during innate immunity. We demonstrate that stromules extend along microtubules (MTs) and MT organization directly affects stromule
Alqarni, Ali, Caplan, Jeffrey Lewis, Dinesh-Kumar, Savithramma P, Hoban, Kyle, Kambhamettu, Chandra, Kumar, Amutha Sampath, McDonald, John H, Modla, Shannon, Nedo, Alexander, Park, Eunsook, Ren, Li   +10 more
core   +3 more sources

Tumor-Infiltrating Immune Cells in Colorectal Cancer [PDF]

Neoplasia
Colorectal cancer encompasses a heterogeneous group of malignancies that differ in pathophysiological mechanisms, immune response and infiltration, therapeutic response, and clinical prognosis. Numerous studies have highlighted the clinical relevance of tumor-infiltrating immune cells among different types of colorectal tumors yet vary in cell type ...
Sonia A.M. Ferkel, Elizabeth A. Holman, Raoul S. Sojwal, Samuel J.S. Rubin, Stephan Rogalla   +4 more
openaire   +4 more sources