Results 41 to 50 of about 6,519,090 (301)

Tumor-Infiltrating Immune Cells in Colorectal Cancer [PDF]

Neoplasia
Colorectal cancer encompasses a heterogeneous group of malignancies that differ in pathophysiological mechanisms, immune response and infiltration, therapeutic response, and clinical prognosis. Numerous studies have highlighted the clinical relevance of tumor-infiltrating immune cells among different types of colorectal tumors yet vary in cell type ...
Sonia A.M. Ferkel, Elizabeth A. Holman, Raoul S. Sojwal, Samuel J.S. Rubin, Stephan Rogalla   +4 more
openaire   +4 more sources

Cancer Cell–Autonomous Parainflammation Mimics Immune Cell Infiltration [PDF]

Cancer Research, 2017
Abstract Parainflammation is a unique variant of inflammation, characterized by epithelial-autonomous activation of inflammatory response. Parainflammation has been shown to strongly promote mouse gut tumorigenesis upon p53 loss. In a recent study, we explored the prevalence of parainflammation in human cancer and determined its ...
Lasry, Audrey, Aran, Dvir, Butte, Atul J, Ben-Neriah, Yinon   +3 more
openaire   +4 more sources

Associations between CDCA2 expression and immune cell infiltration in LGG.

, 2023
(A) The correlation between CDCA2 and immune cell infiltration; (B, C, D) The correlation between CDCA2 and stromalscore, immune score and estimate score; (E) The differential expression of immune cells in the high and low CDCA2 expression groups in LGG;
Wenle Li (1234731), Chengjie Xu (9231483), Zhenzhe Li (7322933), Wensheng Li (309393), Dong Lv (3355730), Huanqiang Liu (17020744), Jieqin Yao (17020738), Boxian Chen (17020741)   +7 more
core   +1 more source

Identification of testicular cancer immune infiltrates and novel immune cell subtypes

FEBS Open Bio, 2023
Testicular germ cell tumors (TGCT) are the most common type of testicular cancer, comprising 90–95% of cases and representing the most prevalent solid malignancy in young adult men. Immune infiltrates play important regulatory roles in tumors, but their role in TGCT remains unclear.
Zhiguo Zhu, Xujun Xuan, Xinkun Wang, Miaomiao Wang, Chunyang Meng, Zhonghai Li   +5 more
openaire   +3 more sources

Correlation analysis between PLAUR expression and immune cell infiltration.

, 2022
A. Correlation between high and low PLAUR expression and ImmuneScore; B. Correlation between Grade and ImmuneScore; C. Correlation between Stage and ImmuneScore; D. Correlation between T stage and ImmuneScore; E.
Zengshu Xing (12837293), Zhiwei Wang (120259), Kunxiong Wang (12837290), Xin Gao (14001), Zhenxiang Liu (534118)   +4 more
core   +1 more source

Immune Cell Infiltration and Tertiary Lymphoid Structures as Determinants of Antitumor Immunity [PDF]

The Journal of Immunology, 2018
Abstract Limited representation of intratumoral immune cells is a major barrier to tumor control. However, simply enhancing immune responses in tumor-draining lymph nodes or through adoptive transfer may not overcome the limited ability of tumor vasculature to support effector infiltration. An alternative is to promote a sustained immune
Victor H Engelhard, Anthony B Rodriguez, Ileana S Mauldin, Amber N Woods, J David Peske, Craig L Slingluff   +5 more
openaire   +2 more sources

Infiltration patterns of immune cells in different groups.

, 2021
(A)Relative percentage of 22 immune cell subsets in tendon disease samples (B) Heat map of immune cell infiltration between tendinopathy group and control group, green represents tendinopathy group, red line represents control group (C) Infiltration ...
Hong Xia (50641), Ya xi Zhu (11624730), Zhao Zhuang (11624739), Yu yang Ming (11624736), Jia qiang Huang (11624733)   +4 more
core   +1 more source

RNF8 enhances the sensitivity of PD-L1 inhibitor against melanoma through ubiquitination of galectin-3 in stroma

Cell Death Discovery, 2023
The failure of melanoma immunotherapy can be mediated by immunosuppression in the tumor microenvironment (TME), and insufficient activation of effector T cells against the tumor.
Yanan Guo, Rong Shen, Keren Yang, Yutong Wang, Haoyun Song, Xiangwen Liu, Xin Cheng, Rile Wu, Yanfeng Song, Degui Wang   +9 more
doaj   +1 more source

Cuproptosis regulator-mediated patterns associated with immune infiltration features and construction of cuproptosis-related signatures to guide immunotherapy

Frontiers in Immunology, 2022
BackgroundLiver hepatocellular carcinoma (HCC) is a prevalent cancer that lacks a sufficiently efficient approach to guide immunotherapy. Additionally, cuproptosis is a recently identified regulated cell death program that is triggered by copper ...
Gongjun Wang, Gongjun Wang, Ruoxi Xiao, Shufen Zhao, Libin Sun, Jing Guo, Wenqian Li, Yuqi Zhang, Xiaoqian Bian, Wensheng Qiu, Shasha Wang   +10 more
doaj   +1 more source

The Prognostic Landscape of Tumor-Infiltrating Immune Cells and Immune Checkpoints in Glioblastoma [PDF]

Technology in Cancer Research & Treatment, 2019
Tumor-infiltrating immune cells are part of a complex microenvironment and associated with improved clinical outcomes in a broad range of tumor types. However, a detailed map for the prognostic landscape of tumor-infiltrating immune cells and immune checkpoint modulators in glioblastoma is still lacking.
Shiman Wu, Wenli Yang, Hua Zhang, Yan Ren, Ziwei Fang, Chengjie Yuan, Zhenwei Yao   +6 more
openaire   +2 more sources