Results 21 to 30 of about 6,100,412 (305)

The Landscape of Immune Cells Infiltrating in Prostate Cancer [PDF]

Frontiers in Oncology, 2020
This study was to explore the infiltration pattern of immune cells in the prostate cancer (PCa) microenvironment and evaluate the possibility of specific infiltrating immune cells as potential prognostic biomarkers in PCa.Infiltrating percentage of 22 immune cells were extracted from 27 normalized datasets by CIBERSORT algorithm. Samples with CIBERSORT
Zhicong Wu, Zhicong Wu, Hua Chen, Wenyang Luo, Hanyun Zhang, Guihuan Li, Fangyin Zeng, Fan Deng   +7 more
openaire   +3 more sources

Characteristics of Infiltrating Immune Cells and a Predictive Immune Model for Cervical Cancer [PDF]

Journal of Cancer, 2021
The role of infiltrating immune cells within the tumor microenvironment has received considerable attention, but their function in cervical cancer remains to be elucidated; thus, comprehensive evaluation of their predictive value is needed. Using cervical cancer samples from 406 patients, immune cell infiltration was evaluated via immunohistochemistry.
Zou, Ruanmin, Gu, Ruihong, Yu, Xia, Hu, Yingying, Yu, Junhui, Xue, Xiangyang, Zhu, Xueqiong   +6 more
openaire   +2 more sources

Immune cell infiltration and immunotherapy in hepatocellular carcinoma

Mathematical Biosciences and Engineering, 2022
<abstract><p>Hepatocellular carcinoma is a highly malignant tumor and patients yield limited benefits from the existing treatments. The application of immune checkpoint inhibitors is promising but the results described in the literature are not favorable.
Yu Jiang, Lijuan Lin, Huiming Lv, He Zhang, Lili Jiang, Fenfen Ma, Qiuyue Wang, Xue Ma, Shengjin Yu   +8 more
openaire   +3 more sources

T-cell metagene predicts a favorable prognosis in estrogen receptor-negative and HER2-positive breast cancers [PDF]

, 2009
Introduction: Lymphocyte infiltration (LI) is often seen in breast cancer but its importance remains controversial. A positive correlation of human epidermal growth factor receptor 2 (HER2) amplification and LI has been described, which was associated ...
Pusztai, Laos, Solbach, Christine, Ahr, André, Karn, Thomas, Liedtke, Cornelia, Gätje, Regine, Hanker, Lars, Holtrich, Uwe, Gaetje, Regine, Rody, Achim, Ruckhäberle, Eugen, Metzler, Dirk, Ruckhaeberle, Eugen, Engels, Knut, Kaufmann, Manfred   +14 more
core   +1 more source

Regression of canine oral papillomas is associated with infiltration of CD4+ and CD8+ lymphocytes [PDF]

, 2001
Canine oral papillomavirus (COPV) infection is used in vaccine development against mucosal papillomaviruses. The predictable, spontaneous regression of the papillomas makes this an attractive system for analysis of cellular immunity.
Nicholls, Philip K., Parry, N.R., Gough, Gerald W., Anderson, Davina M., Gough, G.W., Stanley, M.A., Parry, Nigel R., Stanley, Margaret A., Nicholls, P.K., Moore, Peter F., Moore, Richard A., Moore, R.A., Anderson, D.M., Moore, P.F.   +13 more
core   +1 more source

New insights from integrated bioinformatics analysis: the role of circadian rhythm disruption and immune infiltration in obstructive sleep apnea disease

Frontiers in Immunology, 2023
BackgroundCircadian rhythm disruption and immune infiltration are both closely associated with the development of Obstructive sleep apnea (OSA) disease and a variety of cardiovascular and neurological complications, but their interactions with OSA ...
Xinyue Zhang, Yixuan Wang, Zhou Pan, Ke Hu   +3 more
doaj   +1 more source

Identification and Validation of Immune Infiltration Phenotypes in Laryngeal Squamous Cell Carcinoma by Integrative Multi-Omics Analysis

Frontiers in Immunology, 2022
BackgroundLaryngeal squamous cell carcinoma (LSCC) is one of the world’s most common head and neck cancer. However, the immune infiltration phenotypes of LSCC have not been well investigated.MethodsThe multi-omics data of LSCC were obtained from the TCGA
Li Yan, Xiaole Song, Gang Yang, Lifen Zou, Yi Zhu, Xiaoshen Wang   +5 more
doaj   +1 more source

The Role of Immune Escape and Immune Cell Infiltration in Breast Cancer [PDF]

Breast Care, 2018
While detailed analysis of aberrant cancer cell signaling pathways and changes in cancer cell DNA has dominated the field of breast cancer biology for years, there now exists increasing evidence that the tumor microenvironment (TME) including tumor-infiltrating immune cells support the growth and development of breast cancer and further facilitate ...
André, Steven, Barbara, Seliger
openaire   +2 more sources

Immune Characteristics in Biliary Atresia Based on Immune Genes and Immune Cell Infiltration

Frontiers in Pediatrics, 2022
BackgroundBiliary atresia (BA) is a serious biliary disease in infancy. Jaundice is the most visual and prominent symptom, and it mainly involves bile duct cells leading to the loss of intrahepatic and extrahepatic bile ducts. If left untreated, it will eventually progress to liver cirrhosis. The pathogenesis of BA is not clear, and it is now generally
Chenyu Yang, Chenyu Yang, Huiwu Xing, Huiwu Xing, Bingqian Tan, Bingqian Tan, Mingman Zhang, Mingman Zhang   +7 more
openaire   +3 more sources

A Transendothelial Leukocyte Transmigration Model Based on Computational Fluid Dynamics and BP Neural Network

Frontiers in Bioengineering and Biotechnology, 2022
The mechanism of immune infiltration involving immune cells is closely related to various diseases. A key issue in immune infiltration is the transendothelial transmigration of leukocytes.
Qingjia Chi, Zichang Yang, Hua-Ping Liang   +2 more
doaj   +1 more source