Results 21 to 30 of about 1,693,225 (311)

Distribution of Tumor-Infiltrating Immune Cells in Glioblastoma [PDF]

open access: yesCNS Oncology, 2018
Evaluation of features related to infiltrating immune cell level in glioblastoma.Tumor-infiltrating lymphocytes (TILs) through H&E staining, and TILs (CD3, CD4, CD8 and CD20) and macrophage (CD68 and CD163) levels through immunohistochemistry were evaluated through digital analysis.CD68 (9.1%), CD163 (2.2%), CD3 (1.6%) and CD8 (1.6%) had the highest ...
Enrique Orrego   +13 more
openaire   +3 more sources

The Landscape of Immune Cells Infiltrating in Prostate Cancer [PDF]

open access: yesFrontiers in Oncology, 2020
This study was to explore the infiltration pattern of immune cells in the prostate cancer (PCa) microenvironment and evaluate the possibility of specific infiltrating immune cells as potential prognostic biomarkers in PCa.Infiltrating percentage of 22 immune cells were extracted from 27 normalized datasets by CIBERSORT algorithm. Samples with CIBERSORT
Zhicong Wu   +7 more
openaire   +3 more sources

CNS fibroblasts form a fibrotic scar in response to immune cell infiltration

open access: yesNature Neuroscience, 2021
Fibrosis is a common pathological response to inflammation in many peripheral tissues and can prevent tissue regeneration and repair. Here, we identified persistent fibrotic scarring in the CNS following immune cell infiltration in the experimental ...
Cayce E. Dorrier   +13 more
semanticscholar   +1 more source

Immune cell infiltration landscape and immune marker molecular typing in preeclampsia [PDF]

open access: yesBioengineered, 2021
Preeclampsia (PE) is an important topic in obstetrics. In this study, we used weighted gene co-expression network analysis (WGCNA) to screen the key modules related to immune cell infiltration and to identify the hub genes for the molecular subtyping of PE. We first downloaded a set of PE transcriptional data (GSE75010; 157 samples: 80 PE and 77 non-PE)
Meng, YiLin, Li, Chuang, Liu, Cai-Xia
openaire   +2 more sources

Identification and Verification of Immune-Related Gene Prognostic Signature Based on ssGSEA for Osteosarcoma

open access: yesFrontiers in Oncology, 2020
Osteosarcoma is the most common malignant bone tumor in children and adolescence. Multiple immune-related genes have been reported in different cancers.
Bo Xiao   +13 more
doaj   +1 more source

Landscape of Immune Microenvironment Under Immune Cell Infiltration Pattern in Breast Cancer

open access: yesFrontiers in Immunology, 2021
Background Increasing evdence supports the suggestion that the immune cell infiltration (ICI) patterns play a pivotal role in tumor progression in breast cancer (BRCA).
Qianhui Xu   +3 more
semanticscholar   +1 more source

Spatially variant immune infiltration scoring in human cancer tissues

open access: yesnpj Precision Oncology, 2022
The Immunoscore is a method to quantify the immune cell infiltration within cancers to predict the disease prognosis. Previous immune profiling approaches relied on limited immune markers to establish patients’ tumor immunity.
Mayar Allam   +9 more
doaj   +1 more source

Identifying Immune Cell Infiltration and Effective Diagnostic Biomarkers in Rheumatoid Arthritis by Bioinformatics Analysis

open access: yesFrontiers in Immunology, 2021
Background Rheumatoid arthritis (RA) is a chronic systemic autoimmune disorder characterized by inflammatory cell infiltration, leading to persistent synovitis and joint destruction. The pathogenesis of RA remains unclear.
Sheng Zhou, Hongcheng Lu, M. Xiong
semanticscholar   +1 more source

Characteristics of Infiltrating Immune Cells and a Predictive Immune Model for Cervical Cancer [PDF]

open access: yesJournal of Cancer, 2021
The role of infiltrating immune cells within the tumor microenvironment has received considerable attention, but their function in cervical cancer remains to be elucidated; thus, comprehensive evaluation of their predictive value is needed. Using cervical cancer samples from 406 patients, immune cell infiltration was evaluated via immunohistochemistry.
Zou, Ruanmin   +6 more
openaire   +2 more sources

PNOC Expressed by B Cells in Cholangiocarcinoma Was Survival Related and LAIR2 Could Be a T Cell Exhaustion Biomarker in Tumor Microenvironment: Characterization of Immune Microenvironment Combining Single-Cell and Bulk Sequencing Technology

open access: yesFrontiers in Immunology, 2021
BackgroundCholangiocarcinoma was a highly malignant liver cancer with poor prognosis, and immune infiltration status was considered an important factor in response to immunotherapy.
Zheng Chen   +17 more
doaj   +1 more source

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