Results 31 to 40 of about 1,693,225 (311)

Tumor Immunometabolism Characterization in Ovarian Cancer With Prognostic and Therapeutic Implications

Frontiers in Oncology, 2021
Metabolic dysregulation in the tumor microenvironment has significant impact on immune infiltration and immune responses. However, interaction between immunity and metabolism in the ovarian microenvironment requires further exploration. We constructed an
Miner Yang, Gaowen Chen, Kunjie Gao, Yifeng Wang   +3 more
doaj   +1 more source

Neoadjuvant chemotherapy is associated with altered immune cell infiltration and an anti-tumorigenic microenvironment in resected pancreatic cancer

Clinical Cancer Research, 2022
Purpose: Neoadjuvant chemotherapy is increasingly administered to patients with resectable or borderline resectable pancreatic ductal adenocarcinoma (PDAC), yet its impact on the tumor immune microenvironment is incompletely understood.
Andressa Dias Costa, Sara A. Väyrynen, A. Chawla, Jinming Zhang, J. Väyrynen, M. Lau, Hannah L. Williams, C. Yuan, V. Morales-Oyarvide, D. Elganainy, Harshabad Singh, J. Cleary, K. Perez, K. Ng, William A. Freed-Pastor, J. Mancias, S. Dougan, Jiping Wang, D. Rubinson, R. Dunne, M. Kozak, L. Brais, Emma C. Reilly, T. Clancy, D. Linehan, D. Chang, A. Hezel, A. Koong, A. Aguirre, B. Wolpin, J. Nowak   +30 more
semanticscholar   +1 more source

Identification of immune cell infiltration and diagnostic biomarkers in unstable atherosclerotic plaques by integrated bioinformatics analysis and machine learning

Frontiers in Immunology, 2022
Objective The decreased stability of atherosclerotic plaques increases the risk of ischemic stroke. However, the specific characteristics of dysregulated immune cells and effective diagnostic biomarkers associated with stability in atherosclerotic ...
Jing Wang, Zijian Kang, Yandong Liu, Zifu Li, Yang Liu, Jianmin Liu   +5 more
semanticscholar   +1 more source

Seven Genes Associated With Lymphatic Metastasis in Thyroid Cancer That Is Linked to Tumor Immune Cell Infiltration

Frontiers in Oncology, 2022
Objective Since there are few studies exploring genes associated with lymphatic metastasis of thyroid carcinoma (THCA), this study was conducted to explore genes associated with lymphatic metastasis of THCA and to investigate the relationship with immune
Linfeng Wu, Yuying Zhou, Yaoyao Guan, Rong-Cheng Xiao, Jia-Liang Cai, Weike Chen, M. Zheng, Kaiting Sun, Chao Chen, Guanli Huang, Xiaogang Zhang, Z. Qian, Shu-rong Shen   +12 more
semanticscholar   +1 more source

Characterization of the Immune Cell Infiltration Landscape in Esophageal Squamous Cell Carcinoma

Frontiers in Oncology, 2022
Background Immunotherapy has achieved remarkable efficacy in treating oesophageal squamous cell carcinoma (ESCC). However, this treatment has limited efficacy in some patients.
Zhi-lin Sui, Xian-xian Wu, Longde Du, Hang Wang, L. Yuan, Jian V. Zhang, Zhentao Yu   +6 more
semanticscholar   +1 more source

Construction and validation of an immune infiltration-related risk model for predicting prognosis and immunotherapy response in low grade glioma

BMC Cancer, 2023
Background Low grade glioma (LGG) is considered a heterogeneous tumor with highly variable survival and limited efficacy of immunotherapy. To identify high-risk subsets and apply immunotherapy effectively in LGG, the status and function of immune ...
Jinna Li, Qing Guo, Rui Xing
doaj   +1 more source

Immune Cell Infiltration into the Brain After Ischemic Stroke in Humans Compared to Mice and Rats: a Systematic Review and Meta-Analysis

Translational Stroke Research, 2021
Although several studies have suggested that anti-inflammatory strategies reduce secondary infarct growth in animal stroke models, clinical studies have not yet demonstrated a clear benefit of immune modulation in patients.
Carolin Beuker, Jan-Kolja Strecker, R. Rawal, Antje Schmidt-Pogoda, T. Ruck, H. Wiendl, L. Klotz, W. Schäbitz, C. Sommer, Heike Minnerup, S. Meuth, J. Minnerup   +11 more
semanticscholar   +1 more source

Identification and Validation of Immune Infiltration Phenotypes in Laryngeal Squamous Cell Carcinoma by Integrative Multi-Omics Analysis

Frontiers in Immunology, 2022
BackgroundLaryngeal squamous cell carcinoma (LSCC) is one of the world’s most common head and neck cancer. However, the immune infiltration phenotypes of LSCC have not been well investigated.MethodsThe multi-omics data of LSCC were obtained from the TCGA
Li Yan, Xiaole Song, Gang Yang, Lifen Zou, Yi Zhu, Xiaoshen Wang   +5 more
doaj   +1 more source

New insights from integrated bioinformatics analysis: the role of circadian rhythm disruption and immune infiltration in obstructive sleep apnea disease

Frontiers in Immunology, 2023
BackgroundCircadian rhythm disruption and immune infiltration are both closely associated with the development of Obstructive sleep apnea (OSA) disease and a variety of cardiovascular and neurological complications, but their interactions with OSA ...
Xinyue Zhang, Yixuan Wang, Zhou Pan, Ke Hu   +3 more
doaj   +1 more source

Abundant expression of ferroptosis-related SAT1 is related to unfavorable outcome and immune cell infiltration in low-grade glioma

BMC Cancer, 2022
Low-grade glioma (LGG) is susceptible to ferroptosis, which is involved in TMZ resistance. Ferroptosis induction can enhance the sensitivity to TMZ and synergistically kill glioma cells.
Yan-hua Mou, Lu Zhang, Zhan-tao Liu, Xiu-jun Song   +3 more
semanticscholar   +1 more source