Results 21 to 30 of about 614,807 (307)
Immune Cell Infiltrate and Prognosis in Gastric Cancer [PDF]
Cancers, 2020 Purpose: To examine and compare the prognostic value of immune cell score (ICS) and Klintrup–Mäkinen (KM) grade in gastric cancer. Methods: Gastric adenocarcinoma tissues from samples of 741 patients surgically treated in two hospitals in Finland were assessed for ICS and KM grade.
Niko Kemi +11 more
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Cancer Cell–Autonomous Parainflammation Mimics Immune Cell Infiltration [PDF]
Cancer Research, 2017 Abstract Parainflammation is a unique variant of inflammation, characterized by epithelial-autonomous activation of inflammatory response. Parainflammation has been shown to strongly promote mouse gut tumorigenesis upon p53 loss. In a recent study, we explored the prevalence of parainflammation in human cancer and determined its ...
Lasry, Audrey +3 more
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Immune Infiltration Landscape in Clear Cell Renal Cell Carcinoma Implications [PDF]
Frontiers in Oncology, 2021 The malignant phenotypes of cancer are defined not only by its intrinsic tumor cells but also by the tumor infiltrating immune cells (TIICs) recruited to the cancer microenvironment. Clear cell renal cell carcinoma (ccRCC) immune microenvironment plays an important role in the tumorigenesis. This research investigated the characteristics of immune cell
Yongfeng Wang +3 more
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Functional Blockade of E-Selectin in Tumor-Associated Vessels Enhances Anti-Tumor Effect of Doxorubicin in Breast Cancer [PDF]
, 2020 Chemotherapy is a mainstay of treatment for solid tumors. However, little is known about how therapy-induced immune cell infiltration may affect therapy response.
Chervoneva, Inna +14 more
core +3 more sources
Infiltration of tumor spheroids by activated immune cells
Physical Biology, 2022 Abstract Recent years have seen a tremendous growth of interest in understanding the role that the adaptive immune system could play in interdicting tumor progression. In this context, it has been shown that the density of adaptive immune cells inside a solid tumor serves as a favorable prognostic marker across different types of ...
Mrinmoy Mukherjee +5 more
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Immune cell infiltration landscape and immune marker molecular typing in preeclampsia [PDF]
Bioengineered, 2021 Preeclampsia (PE) is an important topic in obstetrics. In this study, we used weighted gene co-expression network analysis (WGCNA) to screen the key modules related to immune cell infiltration and to identify the hub genes for the molecular subtyping of PE. We first downloaded a set of PE transcriptional data (GSE75010; 157 samples: 80 PE and 77 non-PE)
Meng, YiLin, Li, Chuang, Liu, Cai-Xia
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Frontiers in Oncology, 2020 Osteosarcoma is the most common malignant bone tumor in children and adolescence. Multiple immune-related genes have been reported in different cancers.
Bo Xiao +13 more
doaj +1 more source
TIMER2.0 for analysis of tumor-infiltrating immune cells [PDF]
Nucleic Acids Research, 2020 Abstract Tumor progression and the efficacy of immunotherapy are strongly influenced by the composition and abundance of immune cells in the tumor microenvironment. Due to the limitations of direct measurement methods, computational algorithms are often used to infer immune cell composition from bulk tumor transcriptome profiles.
X Shirley Liu +7 more
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Frontiers in Immunology, 2020 Background: The tumor microenvironment (TME) consists of heterogeneous cell populations, including malignant cells and nonmalignant cells that support tumor proliferation, invasion, and metastasis through extensive cross talk.
Shuguang Zuo +5 more
doaj +1 more source
Spatially variant immune infiltration scoring in human cancer tissues
npj Precision Oncology, 2022 The Immunoscore is a method to quantify the immune cell infiltration within cancers to predict the disease prognosis. Previous immune profiling approaches relied on limited immune markers to establish patients’ tumor immunity.
Mayar Allam +9 more
doaj +1 more source