Results 261 to 270 of about 406,045 (339)

Immune Checkpoint Inhibitor-Associated Myocarditis With Multisystem Immune Toxicity in Renal Cell Carcinoma. [PDF]

JACC Case Rep
Chennuri RN, Madine M, Prathipati R, Mannam R, Reddy SR, Davala P, Chilana JK, Bari F.   +7 more
europepmc   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

DJ-1 inhibition reshapes tumor microenvironment and potentiates immune checkpoint inhibitors. [PDF]

Sci Adv
Zhu H, Lin Y, Jiang L, Zhao W, Chen M, Lu B, Zhou Z, He Q, Yang B, Tomek P, Zhao W, Cao J.   +11 more
europepmc   +1 more source

Supplementary Figure 5 from Immune Checkpoint Blockade Delays Cancer Development and Extends Survival in DNA Polymerase Mutator Syndromes

Akshada Sawant, Fuqian Shi, Eduardo Cararo Lopes, Zhixian Hu, Somer Abdelfattah, Jennele Baul, Jesse R. Powers, Christian S. Hinrichs, Joshua D. Rabinowitz, Chang S. Chan, Edmund C. Lattime, Shridar Ganesan, Eileen White   +12 more
openalex   +1 more source

Glutamine Deprivation Triggers Tribbles Homolog 3 Dependent G‐Quadruplex Resolution to Maintain DNA Repair and Tumor Survival

Advanced Science, EarlyView.
Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji, Xuedan Sun, Zhangran Sun, Mengfan Li, Xinyu Cheng, Shuai Tian, Rick F. Thorne, Jinming Li, Guangzhi Liu, Mian Wu, Xiaoying Liu   +10 more
wiley   +1 more source

Acetaminophen interactions with immune checkpoint inhibitors: guilt by association? [PDF]

J Immunother Cancer
de Lemos ML, de Lemos J, Kletas V, Latt R, Mucovic J.   +4 more
europepmc   +1 more source

Table S5 from The Tumor Microbiome as a Predictor of Outcomes in Patients with Metastatic Melanoma Treated with Immune Checkpoint Inhibitors

Caroline E. Wheeler, Samuel S. Coleman, Rebecca Hoyd, Griffin Caryotakis, Louis Denko, Carlos H.F. Chan, Michelle L. Churchman, Nicholas Denko, Rebecca D. Dodd, Islam Eljilany, Sheetal Hardikar, Marium Husain, Alexandra P. Ikeguchi, Ning Jin, Qin Ma, Martin D. McCarter, Afaf E.G. Osman, Lary A. Robinson, Eric A. Singer, Gabriel Tinoco, Cornelia M. Ulrich, Yousef Zakharia, Daniel Spakowicz, Ahmad A. Tarhini, Aik Choon Tan   +24 more
openalex   +1 more source

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity

Advanced Science, EarlyView.
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu, Lingyao Zeng, Xulin Gan, Yilin Zhou, Han Shen, Dan Wu, Xin Shou, Minmin Jiang, Liyun Shi   +8 more
wiley   +1 more source

Breaking Barriers: Immune Checkpoint Inhibitors in Breast Cancer. [PDF]

Pharmaceutics
Dmuchowski B, Hryniewicz WW, Barczak I, Fręśko K, Szarzyńska Z, Węclewski H, Ślężak JK, Dobosz P, Gryczka H.   +8 more
europepmc   +1 more source

Additional file 3 of Peripheral lymphocyte count as a prognostic marker in cervical cancer patients treated with immune checkpoint inhibitors: a retrospective study

Dofutsu, Mihoko, Aichi, Masahiro, Itai, Toshiyuki, Shinoda, Satoru, Kamiya, Natsuko, Cho, Tamaki, Ogawara, Yuki, Ishidera, Yumi, Imai, Yuichi, Miyagi, Etsuko, Mizushima, Taichi   +10 more
openalex   +1 more source