Results 11 to 20 of about 1,810,595 (288)
Negative Immune Checkpoint Inhibitors
PharmaceuticsCheckpoint inhibitors are a modern therapeutic approach for treating various types of cancer, metabolic diseases, and chronic infections. The main goal of this therapy is to specifically unlock the immune system, allowing it to recognize and eliminate ...
Magda Drewniak-Świtalska +2 more
doaj +4 more sources
Immune checkpoint inhibitors [PDF]
Journal of Cell Biology, 2019 Hui details the cell biology underlying the action of immune checkpoint ...
Hui, Enfu, Enfu Hui
core +10 more sources
Brazilian Journal of Oncology, 2022 Objectives: To report real-world data of a cohort of patients treated with immune-checkpoint inhibitors in Brazil, with focus in immune-related adverse events.
Maria Paula Furtado Santos +9 more
doaj +2 more sources
Cardiotoxicity of immune checkpoint inhibitors [PDF]
ESMO Open, 2017 Cardiac toxicity after conventional antineoplastic drugs (eg, anthracyclines) has historically been a relevant issue. In addition, targeted therapies and biological molecules can also induce cardiotoxicity.
Gilda Varricchi +15 more
core +4 more sources
Systematic Review of the Safety of Immune Checkpoint Inhibitors Among Kidney Transplant Patients
Kidney International Reports, 2020 Introduction: Kidney transplant (Ktx) recipients are excluded from clinical trials of immune checkpoint inhibitors. The aim of this systematic review was to assess the safety of immune checkpoint inhibitors among Ktx patients.
Sandhya Manohar +4 more
doaj +3 more sources
Immune Checkpoint Inhibitors in Gliomas
Current Oncology Reports, 2017 PURPOSE OF REVIEW: Malignant gliomas result in disproportionately high morbidity and mortality compared with other primary tumors, and progression of disease is inevitable.
AB Heimberger (14461521) +2 more
core +3 more sources
Immune Checkpoint Inhibitors in HBV-Caused Hepatocellular Carcinoma Therapy
Vaccines, 2023 Hepatitis B virus (HBV) infection is the main risk factor for the development of hepatocellular carcinoma (HCC), the most common type of liver cancer, with high incidence and mortality worldwide.
Jin Zhang +5 more
doaj +2 more sources
Perioperative immune-checkpoint inhibitors for muscle-invasive bladder cancer [PDF]
Drugs in ContextMuscle-invasive bladder cancer (MIBC) has a high risk of recurrence following radical cystectomy. Neoadjuvant cisplatin-based chemotherapy has been used for decades to lower recurrence rates but a significant proportion of patients still have disease ...
Albert Jang +6 more
doaj +2 more sources
Immune checkpoint inhibitors [PDF]
Journal of Experimental Medicine, 2021 Three papers by James Allison and Tasuku Honjo published in JEM between 1995 and 2000 crystallized seminal insights into the role of CTLA-4 and PD-1 in immunosuppression (Krummel and Allison. 1995. J. Exp. Med.https://doi.org/10.1084/jem.182.2.459; van Elsas et al. 1999. J. Exp. Med.https://doi.org/10.1084/jem.190.3.355; Freeman et al. 2000. J.
Kroemer, Guido, Zitvogel, Laurence
openaire +4 more sources
Ionic modulation of immune checkpoint proteins [PDF]
, 2019 Despite extensive basic and clinical research on immune checkpoint regulatory pathways, little is known about the effects of the ionic tumour microenvironment on immune checkpoint expression and function.
Lawrence, Samantha +3 more
core +6 more sources