Results 131 to 140 of about 2,772,829 (401)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

IGF2BP3 overexpression predicts poor prognosis and correlates with immune infiltration in bladder cancer [PDF]

, 2023
Wei Huang, Lizhen Zhu, Haoxuan Huang, Yuanyuan Li, Gongxian Wang, Cheng Zhang   +5 more
openalex   +1 more source

Immune Cell Infiltrates in Atypical Teratoid/Rhabdoid Tumors [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2012
Objective:Atypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant tumor of the central nervous system. Its pathogenesis remains unknown. Like glioblastomas, AT/RTs contain brain cancer stem cells (CSCs) that suppress the immunity of patients and are resistant to conventional chemotherapy and radiation therapy. Considerable infiltration of immune
Jian-Qiang, Lu, Beverly A, Wilson, V Wee, Yong, Jeffrey, Pugh, Vivek, Mehta   +4 more
openaire   +2 more sources

ncRNA-Mediated High Expression of LPCAT1 Correlates with Poor Prognosis and Tumor Immune Infiltration of Liver Hepatocellular Carcinoma

Journal of Immunology Research, 2022
Purpose. To investigate the expression of LPCAT1 in liver hepatocellular carcinoma (LIHC) and its relationship with prognosis and immune infiltration and predict its upstream nonencoding RNAs (ncRNAs). Method.
Qiu Sun, Xudong Liu, Qunlong Peng, Lei Hu, Xiaochun Jiang   +4 more
doaj   +1 more source

Shh production and Gli signaling is activated in vivo in lung, enhancing the Th2 response during a murine model of allergic asthma [PDF]

, 2017
The pathophysiology of allergic asthma is driven by T-helper 2 (Th2) immune responses following aeroallergen inhalation. The mechanisms that initiate, potentiate and regulate airways allergy are incompletely characterized.
Crompton, Tessa, Furmanski, Anna L., Ross, Rosie, Standing, Ariane S.I., Yánez, Diane C.   +4 more
core   +3 more sources

Pan-Cancer and Single-Cell Analysis Reveals CENPL as a Cancer Prognosis and Immune Infiltration-Related Biomarker

Frontiers in Immunology, 2022
Background Centromere protein L (CENPL) is an important member of the centromere protein (CENP) family. However, the correlation between CENPL expression and cancer development and immune infiltration has rarely been studied. Here, we studied the role of
Ziyang Feng, Yu Chen, Changjing Cai, Jun Tan, Ping Liu, Yihong Chen, Hong Shen, S. Zeng, Ying Han   +8 more
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Identification of key pathways, genes and immune cell infiltration in hypoxia of high-altitude acclimatization via meta-analysis and integrated bioinformatics analysis [PDF]

, 2023
Qiong Li, Zhichao Xu, Fujin Fang, Yan Shen, Huan Lei, Xiaobing Shen   +5 more
openalex   +1 more source

Integrated analysis of single-cell and bulk RNA-seq reveals MAGEA3/6-associated immune subtypes and key immune genes in gastric cancer.

PLoS ONE
The immune microenvironment is critical in gastric cancer (GC), yet epithelial-specific genes linked to immune infiltration remain poorly defined.
Linen Li, Hao Chen, Feng Zhou, Yanqing Shi   +3 more
doaj   +1 more source

A novel anoikis-related prognostic signature associated with prognosis and immune infiltration landscape in clear cell renal cell carcinoma

Frontiers in Genetics, 2022
Background: Clear cell renal cell carcinoma (ccRCC) is the most common histological subtype of renal cell carcinoma (RCC). Anoikis plays an essential function in tumourigenesis, whereas the role of anoikis in ccRCC remains unclear.
Zhuo Chen, Xiao Liu, Zhengjie Zhu, Jin-chao Chen, Chen Wang, Xi Chen, Shao-xing Zhu, Aiqin Zhang   +7 more
semanticscholar   +1 more source