Results 111 to 120 of about 1,707,239 (310)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Transcriptomic Insights into Hub Genes, Immune Infiltration, and Candidate Drugs in Erosive Esophagitis [PDF]

open access: yes
Ye Zhao,1,* Xi Chen,1,* Yuhan Huang,2,* Zhihan Zhang,3 Kui Wang,1 Duowu Zou,1 Teng Ma2 1Department of Gastroenterology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Department of ...
Huang Y   +6 more
core  

Prediction of the immune estimation and immune infiltration in human CRC.

open access: yes, 2023
A. Level of infiltration and relative abundance of different immune cells in the CRC tissue samples. Correlation between the translational expression of B. WFDC2, C. TTLL12, D. THRA, and E.
Amit Kumar Dey (10035622)   +2 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Screening of Diagnostic Biomarkers and Immune Infiltration Characteristics Linking Rheumatoid Arthritis and Rosacea Based on Bioinformatics Analysis [PDF]

open access: yes
Yun Wang,1 Jun Chen,1 Zheng-Yu Shen,1 Jie Zhang,2 Yu-Jie Zhu,1 Xu-Qiong Xia1 1Department of Dermatology, Shanghai Ninth People’s Hospital Affiliated Shanghai JiaoTong University School of Medicine, Shanghai, 200080, People’s Republic of China; 2The ...
Chen J   +5 more
core  

Prognosis poor, immune infiltration of colon adenocarcinoma associated with low expression levels of calcium-activated chloride channel

open access: yes
The calcium-activated chloride channel (CLCA4) in colon adenocarcinoma (COAD) and immunological infiltration have not been extensively studied. This work thoroughly employed several datasets to assess the expression, prognosis, and association between ...
Xueying Zhao   +4 more
core   +1 more source

Teratoma formation and immune cell infiltration after syngeneic iPSC transplantation.

open access: yes, 2013
(A), iPSCs in ischemic syngeneic hearts formed visible teratomas 4w after transplantation; (B), Pluripotent cells expressing SSEA-1 and typical tri-germ layer structures could be observed in teratomas; (C), immune cell infiltration inside the graft, 1w ...
Xinyu Wen (3693)   +12 more
core   +1 more source

The landscape of immune infiltration in HCC.

open access: yes, 2020
(A) The different immune infiltration of 22 tumor-infiltrating immune cells (TIICs) between HCC and paired normal tissue; (B) The difference of TIICs proportions and CIBERSORT p-value; (C) The association between immune cytolytic activity and CIBERSORT p-
Min Jiao (2221057)   +11 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Role of Cellular Senescence Genes and Immune Infiltration in Sepsis and Sepsis-Induced ARDS Based on Bioinformatics Analysis [PDF]

open access: yes
Xiao-ling Wu, Ya-nan Guo Intensive Care Unit, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of ChinaCorrespondence: Ya-nan Guo, Intensive Care Unit, The Central Hospital of ...
Wu XL, Guo YN
core  

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