Results 91 to 100 of about 1,838,932 (310)

Identification of Two Novel Immune Subtypes Characterized by Distinct Prognosis and Tumor Microenvironment in Osteosarcoma

Journal of Immunology Research, 2022
Osteosarcoma is a kind of primary malignant tumor of bone. In recent years, its therapeutic effect and prognostic survival are dissatisfactory. The tumor immune microenvironment (TIME) reflects immune status of patients, but it is little known in ...
Shunhan Yao, Meiling Deng, Xiaojing Du, Qingfeng Chen, Rongzhi Huang   +4 more
doaj   +1 more source

Tumor-Infiltrating Immune Cells in Colorectal Cancer [PDF]

Neoplasia
Colorectal cancer encompasses a heterogeneous group of malignancies that differ in pathophysiological mechanisms, immune response and infiltration, therapeutic response, and clinical prognosis. Numerous studies have highlighted the clinical relevance of tumor-infiltrating immune cells among different types of colorectal tumors yet vary in cell type ...
Sonia A.M. Ferkel, Elizabeth A. Holman, Raoul S. Sojwal, Samuel J.S. Rubin, Stephan Rogalla   +4 more
openaire   +4 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Exploring LTB-mediated T cell differentiation as a prognostic marker in triple-negative breast cancer

Breast Cancer Research
Immune infiltration in triple-negative breast cancer (TNBC) is associated with patient prognosis. However, the precise phenotypic classifications of immune infiltration in TNBC remain unclear, and the key regulatory mechanisms underlying this process ...
Xuekai Wang, Yingxiao Ni, Yang Shi, Xiaofeng Yu, Chenchen Wu, Zhuo Xiang, Wei Lv, Qiang Wang   +7 more
doaj   +1 more source

The correlations of AQPs expression with immune infiltration level in ccRCC.

, 2022
The correlations of AQPs expression with immune infiltration level in ccRCC.
Tie Chong (655561), Haibin Zhou (573069), Mei Gao (503320), Mingrui Li (2567635), Yibing Guan (9417680), Juanhua Tian (9417686), Fangshi Xu (9417683), Ziyan Wan (9417689), Minxin He (12085178)   +8 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Leveraging machine learning models to evaluate immune infiltration in the ovarian cancer microenvironment: a single-cell analysis approach

Discover Oncology
Background The prognosis of ovarian cancer is closely related to the degree of immune cell infiltration within the tumor microenvironment. However, current methods for assessing immune infiltration have certain subjective limitations. This study aimed to
Jie Liu, Baoguo Xia, Bingxin Li, Hui Liang   +3 more
doaj   +1 more source

CCR2+ migratory macrophages with M1 status are the early-responders in the cornea of HSV-1 infected mice.

PLoS ONE, 2019
Complex interactions between HSV-1 and infiltrating immune cells play important roles in establishing localized, acute virus replication as well as chronic latent infection. The extent and duration of initial virus replication are the key determinants of
Dhong Hyun Lee, Ujjaldeep Jaggi, Homayon Ghiasi   +2 more
doaj   +1 more source

Correlation between LINC00324 expression and immune infiltration.

Correlation between LINC00324 expression and immune infiltration.
Zhengquan Yu (606806), Kecheng Shen (18258250), Jiang Wu (174815), Jingyu Gu (197190), Xin Jin (108988), Ziqian Yin (16021910), Jiandong Zhu (14110324), Shengjun Shi (365824), Haoyun Yu (18258247)   +8 more
core   +1 more source

Correlation analysis between PLAUR expression and the relative content of immune cell infiltration.

, 2022
Correlation analysis between PLAUR expression and the relative content of immune cell infiltration.
Zengshu Xing (12837293), Zhiwei Wang (120259), Kunxiong Wang (12837290), Xin Gao (14001), Zhenxiang Liu (534118)   +4 more
core   +1 more source