Results 71 to 80 of about 1,707,239 (310)

Characterizing the Tumor Microenvironment and Its Prognostic Impact in Breast Cancer

Cells
The tumor microenvironment (TME) is crucial in cancer development and therapeutic response. Immunotherapy is increasingly recognized as a critical component of cancer treatment.
Wenjuan Zhang, Alex Lee, Amit K. Tiwari, Mary Qu Yang   +3 more
doaj   +1 more source

Regression of canine oral papillomas is associated with infiltration of CD4+ and CD8+ lymphocytes [PDF]

, 2001
Canine oral papillomavirus (COPV) infection is used in vaccine development against mucosal papillomaviruses. The predictable, spontaneous regression of the papillomas makes this an attractive system for analysis of cellular immunity.
Nicholls, Philip K., Parry, N.R., Gough, Gerald W., Anderson, Davina M., Gough, G.W., Stanley, M.A., Parry, Nigel R., Stanley, Margaret A., Nicholls, P.K., Moore, Peter F., Moore, Richard A., Moore, R.A., Anderson, D.M., Moore, P.F.   +13 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Relationship Between Expressions of SDHx Genes and Immune Cell Infiltration in Pheochromocytoma/Paraganglioma

Xiehe Yixue Zazhi
ObjectiveTo investigate the characteristics and differences of immune cell infiltration between different SDHx gene expression and pheochromocytoma/paraganglioma(PPGL).MethodsRNAseqdata of PPGL were downloaded and organized from The Cancer Genome Atlas ...
WANG Pu, GAO Liming, ZHANG Wenyang, YE Ting, LI Hongyan, GUO Rui   +5 more
doaj   +1 more source

MLK4 mRNA expression level is related to immune cell infiltration.

, 2023
A. ESTIMATE was used to analyze the correlation between MLK4 and immune cell infiltration in cervical cancer B. The correlation between MLK4 and immune program was analyzed by IPS; C. Four different algorithms were used to analyze the correlation between
Li Hong (426614), Fujin Shen (16851498), Yang Li (7082), Meng Gong (5170457), Lei Ming (1807879)   +4 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Manufacturing of Composites by Pressure Infiltration, Structure and Mechanical Properties [PDF]

, 2008
This paper presents the possibility of composite block production by using pressure infiltration technology. This method uses the pressure of an inert gas (usually argon or nitrogen) to force the melted matrix material to infiltrate the reinforcing ...
Dobránszky, János, Orbulov, Imre Norbert, Németh, Árpád   +2 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Integrated analysis of single-cell and bulk RNA-seq reveals MAGEA3/6-associated immune subtypes and key immune genes in gastric cancer.

PLoS ONE
The immune microenvironment is critical in gastric cancer (GC), yet epithelial-specific genes linked to immune infiltration remain poorly defined.
Linen Li, Hao Chen, Feng Zhou, Yanqing Shi   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source