Results 21 to 30 of about 2,772,829 (401)

Immune infiltrating cells in duodenal cancers [PDF]

Journal of Translational Medicine, 2020
Abstract Background Duodenal adenocarcinoma (DA) is a rare yet aggressive malignancy, with increasing incidence in the last decades. Its low frequency has hampered a thorough understanding of the pathogenesis of the disease and of its biology, limiting the identification of tailored therapeutic options.
Donisi, G., Capretti, G., Cortese, N., Rigamonti, A., Gavazzi, F., Nappo, G., Pulvirenti A, Sollai, M., Spaggiari, P., Zerbi, A., Marchesi, F   +20 more
openaire   +3 more sources

DFNA5 regulates immune cells infiltration and exhaustion [PDF]

Cancer Cell International, 2022
Abstract Background DFNA5 (GSDME) belongs to Gasdermin familily that is involved in a variety of cancers and triggers cell pyroptosis after chemical treatment. However, the relationship in DFNA5 between prognosis and immune cells in diverse cancers has been receiving little attention.
Jian Hu, Wenceng Pei, Minren Jiang, Ying Huang, Fuyun Dong, Zhenyou Jiang, Ying Xu, Zihuang Li   +7 more
openaire   +3 more sources

Role of mitochondrial metabolic disorder and immune infiltration in diabetic cardiomyopathy: new insights from bioinformatics analysis

Journal of Translational Medicine, 2023
Background Diabetic cardiomyopathy (DCM) is one of the common cardiovascular complications of diabetes and a leading cause of death in diabetic patients.
Cheng Peng, Yanxiu Zhang, Xueyan Lang, Yao Zhang   +3 more
semanticscholar   +1 more source

Role of Rip2 in development of tumor-infiltrating MDSCs and bladder cancer metastasis. [PDF]

, 2014
Tumor invasion and metastases represent a complex series of molecular events that portends a poor prognosis. The contribution of inflammatory pathways mediating this process is not well understood. Nod-like receptors (NLRs) of innate immunity function as
Chin, Arnold I, Zhang, Hanwei
core   +9 more sources

Potential diagnostic biomarkers: 6 cuproptosis- and ferroptosis-related genes linking immune infiltration in acute myocardial infarction

Genes and Immunity, 2023
The current diagnostic biomarkers of acute myocardial infarction (AMI), troponins, lack specificity and exist as false positives in other non-cardiac diseases.
Mengdan Miao, Shan-Hu Cao, Yifei Tian, Dan Liu, Lixia Chen, Qiaoying Chai, Mei Wei, Shaoguang Sun, Le Wang, S. Xin, Gang Liu, Mingqi Zheng   +11 more
semanticscholar   +1 more source

Construction and validation of an immune infiltration-related risk model for predicting prognosis and immunotherapy response in low grade glioma

BMC Cancer, 2023
Background Low grade glioma (LGG) is considered a heterogeneous tumor with highly variable survival and limited efficacy of immunotherapy. To identify high-risk subsets and apply immunotherapy effectively in LGG, the status and function of immune ...
Jinna Li, Qing Guo, Rui Xing
doaj   +1 more source

Interaction, immune infiltration characteristics and prognostic modeling of efferocytosis-related subtypes in glioblastoma

BMC Medical Genomics, 2023
Background Efferocytosis is a biological process in which phagocytes remove apoptotic cells and vesicles from tissues. This process is initiated by the release of inflammatory mediators from apoptotic cells and plays a crucial role in resolving ...
Songyun Zhao, Qi Wang, Yuankun Liu, Pengpeng Zhang, Wei Ji, Jiaheng Xie, Chao Cheng   +6 more
semanticscholar   +1 more source

Combined PD-1/PD-L1 and tumor-infiltrating immune cells redefined a unique molecular subtype of high-grade serous ovarian carcinoma

BMC Genomics, 2022
Background High-grade serous ovarian carcinoma is highly heterogeneous, and although many studies have been conducted to identify high-grade serous ovarian carcinoma molecular subtypes that are sensitive to immunotherapy, no precise molecular subtype has
Ping Liu, Ruoxu Chen, Xudong Zhang, Ruiting Fu, Lin Tao, Wei Jia   +5 more
doaj   +1 more source

Identification of autophagy-related genes in osteoarthritis articular cartilage and their roles in immune infiltration

Frontiers in Immunology, 2023
Background Autophagy plays a critical role in the progression of osteoarthritis (OA), mainly by regulating inflammatory and immune responses. However, the underlying mechanisms remain unclear.
Jun Qin, Jin Zhang, Jian-Jun Wu, Xiao Ru, Qiu-Ling Zhong, Jin-Min Zhao, Ni-Han Lan   +6 more
semanticscholar   +1 more source

Mitophagy and immune infiltration in vitiligo: evidence from bioinformatics analysis

Frontiers in Immunology, 2023
Background Vitiligo is an acquired, autoimmune, depigmented skin disease with unclear pathogenesis. Mitochondrial dysfunction contributes significantly to vitiligo, and mitophagy is vital for removing damaged mitochondria.
Lingling Luo, Jing Zhu, Youming Guo, Chengrang Li   +3 more
semanticscholar   +1 more source