Results 21 to 30 of about 2,585,977 (417)

Role of mitochondrial metabolic disorder and immune infiltration in diabetic cardiomyopathy: new insights from bioinformatics analysis

Journal of Translational Medicine, 2023
Background Diabetic cardiomyopathy (DCM) is one of the common cardiovascular complications of diabetes and a leading cause of death in diabetic patients.
Cheng Peng, Yanxiu Zhang, Xueyan Lang, Yao Zhang   +3 more
semanticscholar   +1 more source

Potential diagnostic biomarkers: 6 cuproptosis- and ferroptosis-related genes linking immune infiltration in acute myocardial infarction

Genes and Immunity, 2023
The current diagnostic biomarkers of acute myocardial infarction (AMI), troponins, lack specificity and exist as false positives in other non-cardiac diseases.
Mengdan Miao, Shan-Hu Cao, Yifei Tian, Dan Liu, Lixia Chen, Qiaoying Chai, Mei Wei, Shaoguang Sun, Le Wang, S. Xin, Gang Liu, Mingqi Zheng   +11 more
semanticscholar   +1 more source

Mitophagy and immune infiltration in vitiligo: evidence from bioinformatics analysis

Frontiers in Immunology, 2023
Background Vitiligo is an acquired, autoimmune, depigmented skin disease with unclear pathogenesis. Mitochondrial dysfunction contributes significantly to vitiligo, and mitophagy is vital for removing damaged mitochondria.
Lingling Luo, Jing Zhu, Youming Guo, Chengrang Li   +3 more
semanticscholar   +1 more source

Comprehensive analysis of cuproptosis-related genes in immune infiltration in ischemic stroke

Frontiers in Neurology, 2023
Background Immune infiltration plays an important role in the course of ischemic stroke (IS) progression. Cuproptosis is a newly discovered form of programmed cell death.
Xuehui Fan, Hongping Chen, Fangchao Jiang, Chen Xu, Yingjun Wang, Haining Wang, Meng Li, Wane Wei, Jihe Song, D. Zhong, Guozhong Li   +10 more
semanticscholar   +1 more source

Role of necroptosis and immune infiltration in essential thrombocytosis. [PDF]

Hereditas
Background Necroptosis, a recently identified form of programmed cell death involved in the pathogenesis of a variety of tumor and non-tumor diseases. Nevertheless, the function of necroptosis in essential thrombocytosis (ET) remains unclear, which is a ...
Li G, Guo Y, Zhang Y.
europepmc   +2 more sources

Construction and validation of an immune infiltration-related risk model for predicting prognosis and immunotherapy response in low grade glioma

BMC Cancer, 2023
Background Low grade glioma (LGG) is considered a heterogeneous tumor with highly variable survival and limited efficacy of immunotherapy. To identify high-risk subsets and apply immunotherapy effectively in LGG, the status and function of immune ...
Jinna Li, Qing Guo, Rui Xing
doaj   +1 more source

Association of High Tumor Mutation Burden in Non–Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels

JAMA Oncology, 2022
Key Points Question Is tumor mutation burden (TMB) associated with improved outcomes of programmed cell death–1 (PD-1)/programmed death ligand–1 (PD-L1) inhibition across PD-L1 expression levels in non–small cell lung cancer (NSCLC)?
B. Ricciuti, Xinan Wang, J. Alessi, H. Rizvi, N. Mahadevan, Yvonne Y. Li, Andrew Polio, James Lindsay, R. Umeton, Rileen Sinha, N. Vokes, G. Recondo, G. Lamberti, M. Lawrence, V. Vaz, G. Leonardi, A. Plodkowski, H. Gupta, A. Cherniack, M. Tolstorukov, B. Sharma, K. Felt, J. Gainor, Arvind Ravi, G. Getz, K. Schalper, B. Henick, P. Forde, V. Anagnostou, P. Jänne, E. V. Van Allen, M. Nishino, L. Sholl, D. Christiani, Xihong Lin, S. Rodig, M. Hellmann, M. Awad   +37 more
semanticscholar   +1 more source

Mechanism of immune infiltration in synovial tissue of osteoarthritis: a gene expression-based study

Journal of Orthopaedic Surgery and Research, 2023
Background Osteoarthritis is a chronic degenerative joint disease, and increasing evidences suggest that the pathogenic mechanism involves immune system and inflammation.
Qingyu Zhang, Chao Sun, Xuchang Liu, Chao Zhu, Chuncheng Ma, Rongjie Feng   +5 more
semanticscholar   +1 more source

Combined PD-1/PD-L1 and tumor-infiltrating immune cells redefined a unique molecular subtype of high-grade serous ovarian carcinoma

BMC Genomics, 2022
Background High-grade serous ovarian carcinoma is highly heterogeneous, and although many studies have been conducted to identify high-grade serous ovarian carcinoma molecular subtypes that are sensitive to immunotherapy, no precise molecular subtype has
Ping Liu, Ruoxu Chen, Xudong Zhang, Ruiting Fu, Lin Tao, Wei Jia   +5 more
doaj   +1 more source

Immune infiltration and immunophenotyping in atrial fibrillation

Aging, 2023
Atrial fibrillation (AF) is a relatively common arrhythmia in clinical practice. Although significant progress has been achieved in the treatment of AF and its associated complications, research on AF prevention lags behind, mainly due to the lack of a ...
Yuqing Tian, Shiying Liu, Yanan Zhang, Jiefu Yang, Peiyao Guo, Hongchao Zhang, Xue Yu, T. Zou   +7 more
semanticscholar   +1 more source