Results 31 to 40 of about 469,505 (262)
Cdx2 regulates immune cell infiltration in the intestine [PDF]
AbstractThe intestinal epithelium is a unique tissue, serving both as a barrier against pathogens and to conduct the end digestion and adsorption of nutrients. As regards the former, the intestinal epithelium contains a diverse repertoire of immune cells, including a variety of resident lymphocytes, macrophages and dendritic cells.
Simon Chewchuk +2 more
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Yunqi Hou,1,* Zhen Chen,2,* Liping Wang,3 Yingxin Deng,1 Genglong Liu,4 Yongfen Zhou,1 Haiqin Shi,1 Xiangqun Shi,1 Qianhua Jiang2 1Department of Neurology, Shunde Hospital, Southern Medical University (The First People’s Hospital of Shunde ...
Hou Y +8 more
doaj
Pancreatic ductal adenocarcinoma (PDAC) is a highly fatal malignancy that is characterized by an immunosuppressive microenvironment. The immune suppression in PDAC is largely driven by heterogeneous stromal and tumor cells.
Xiaomeng Liu +9 more
doaj +1 more source
Immune Characteristics in Biliary Atresia Based on Immune Genes and Immune Cell Infiltration
BackgroundBiliary atresia (BA) is a serious biliary disease in infancy. Jaundice is the most visual and prominent symptom, and it mainly involves bile duct cells leading to the loss of intrahepatic and extrahepatic bile ducts. If left untreated, it will eventually progress to liver cirrhosis. The pathogenesis of BA is not clear, and it is now generally
Chenyu Yang +7 more
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Hepatocellular carcinoma (HCC) has a high degree of malignancy and a poor prognosis. Immune infiltration-related genes have shown good predictive value in the prognosis of many solid tumours.
Kunfu Dai +4 more
doaj +1 more source
The Role of Immune Escape and Immune Cell Infiltration in Breast Cancer [PDF]
While detailed analysis of aberrant cancer cell signaling pathways and changes in cancer cell DNA has dominated the field of breast cancer biology for years, there now exists increasing evidence that the tumor microenvironment (TME) including tumor-infiltrating immune cells support the growth and development of breast cancer and further facilitate ...
André, Steven, Barbara, Seliger
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Prostate cancer (PCa) is a urological malignancy with poor prognosis. Immune-related genes are associated with immune infiltration in prostate cancer, but their role in immunogenic PCa is less well understood.
Wenkang Niu, Tingting Zhang, Lei Ma
doaj +1 more source
Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer [PDF]
The host immune reaction is represented by immune/inflammatory cell infiltrates. Here we systematically analysed tumour-infiltrating immune/inflammatory cells in pancreatic ductal carcinoma (PDC) and evaluated their clinicopathological impact.Using immunohistochemistry, we examined tumour-infiltrating CD68(+) pan-macrophages, HLA-DR(+)CD68(+) M1 ...
Ino, Y +6 more
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Association of SMC4 with prognosis and immune infiltration of sarcoma
This study was performed to explore the prognostic relevance of structural maintenance of chromosomes 4 (SMC4) in pan-cancer and explore the association between SMC4 and immune infiltration of sarcoma.Elevated expression of SMC4 was detected in cancer tissues compared to normal tissue, which was confirmed in synovial sarcoma tissues with ...
Jiang, Guangyao +6 more
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BackgroundThe tumor microenvironment (TME) involves infiltration of multiple immune cell subsets, which could influence the prognosis and clinical characteristics.
Dan Liu, Xue Yang, Xiongzhi Wu
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