Results 31 to 40 of about 469,505 (262)

Cdx2 regulates immune cell infiltration in the intestine [PDF]

open access: yesScientific Reports, 2021
AbstractThe intestinal epithelium is a unique tissue, serving both as a barrier against pathogens and to conduct the end digestion and adsorption of nutrients. As regards the former, the intestinal epithelium contains a diverse repertoire of immune cells, including a variety of resident lymphocytes, macrophages and dendritic cells.
Simon Chewchuk   +2 more
openaire   +3 more sources

Characterization of Immune-Related Genes and Immune Infiltration Features in Epilepsy by Multi-Transcriptome Data

open access: yesJournal of Inflammation Research, 2022
Yunqi Hou,1,* Zhen Chen,2,* Liping Wang,3 Yingxin Deng,1 Genglong Liu,4 Yongfen Zhou,1 Haiqin Shi,1 Xiangqun Shi,1 Qianhua Jiang2 1Department of Neurology, Shunde Hospital, Southern Medical University (The First People’s Hospital of Shunde ...
Hou Y   +8 more
doaj  

Intra-tumoral infiltration of adipocyte facilitates the activation of antitumor immune response in pancreatic ductal adenocarcinoma

open access: yesTranslational Oncology, 2023
Pancreatic ductal adenocarcinoma (PDAC) is a highly fatal malignancy that is characterized by an immunosuppressive microenvironment. The immune suppression in PDAC is largely driven by heterogeneous stromal and tumor cells.
Xiaomeng Liu   +9 more
doaj   +1 more source

Immune Characteristics in Biliary Atresia Based on Immune Genes and Immune Cell Infiltration

open access: yesFrontiers in Pediatrics, 2022
BackgroundBiliary atresia (BA) is a serious biliary disease in infancy. Jaundice is the most visual and prominent symptom, and it mainly involves bile duct cells leading to the loss of intrahepatic and extrahepatic bile ducts. If left untreated, it will eventually progress to liver cirrhosis. The pathogenesis of BA is not clear, and it is now generally
Chenyu Yang   +7 more
openaire   +3 more sources

Identification of immune infiltration-related genes as prognostic indicators for hepatocellular carcinoma

open access: yesBMC Cancer, 2022
Hepatocellular carcinoma (HCC) has a high degree of malignancy and a poor prognosis. Immune infiltration-related genes have shown good predictive value in the prognosis of many solid tumours.
Kunfu Dai   +4 more
doaj   +1 more source

The Role of Immune Escape and Immune Cell Infiltration in Breast Cancer [PDF]

open access: yesBreast Care, 2018
While detailed analysis of aberrant cancer cell signaling pathways and changes in cancer cell DNA has dominated the field of breast cancer biology for years, there now exists increasing evidence that the tumor microenvironment (TME) including tumor-infiltrating immune cells support the growth and development of breast cancer and further facilitate ...
André, Steven, Barbara, Seliger
openaire   +2 more sources

Correlation analysis between immune-related genes and cell infiltration revealed prostate cancer immunotherapy biomarkers linked to T cells gamma delta

open access: yesScientific Reports, 2023
Prostate cancer (PCa) is a urological malignancy with poor prognosis. Immune-related genes are associated with immune infiltration in prostate cancer, but their role in immunogenic PCa is less well understood.
Wenkang Niu, Tingting Zhang, Lei Ma
doaj   +1 more source

Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer [PDF]

open access: yesBritish Journal of Cancer, 2013
The host immune reaction is represented by immune/inflammatory cell infiltrates. Here we systematically analysed tumour-infiltrating immune/inflammatory cells in pancreatic ductal carcinoma (PDC) and evaluated their clinicopathological impact.Using immunohistochemistry, we examined tumour-infiltrating CD68(+) pan-macrophages, HLA-DR(+)CD68(+) M1 ...
Ino, Y   +6 more
openaire   +2 more sources

Association of SMC4 with prognosis and immune infiltration of sarcoma

open access: yesAging, 2023
This study was performed to explore the prognostic relevance of structural maintenance of chromosomes 4 (SMC4) in pan-cancer and explore the association between SMC4 and immune infiltration of sarcoma.Elevated expression of SMC4 was detected in cancer tissues compared to normal tissue, which was confirmed in synovial sarcoma tissues with ...
Jiang, Guangyao   +6 more
openaire   +2 more sources

Tumor Immune Microenvironment Characterization Identifies Prognosis and Immunotherapy-Related Gene Signatures in Melanoma

open access: yesFrontiers in Immunology, 2021
BackgroundThe tumor microenvironment (TME) involves infiltration of multiple immune cell subsets, which could influence the prognosis and clinical characteristics.
Dan Liu, Xue Yang, Xiongzhi Wu
doaj   +1 more source

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