Results 41 to 50 of about 1,707,239 (310)

Intra-tumoral infiltration of adipocyte facilitates the activation of antitumor immune response in pancreatic ductal adenocarcinoma

Translational Oncology, 2023
Pancreatic ductal adenocarcinoma (PDAC) is a highly fatal malignancy that is characterized by an immunosuppressive microenvironment. The immune suppression in PDAC is largely driven by heterogeneous stromal and tumor cells.
Xiaomeng Liu, Jiang Liu, Jin Xu, Bo Zhang, Miaoyan Wei, Jialin Li, Hang Xu, Xianjun Yu, Wei Wang, Si Shi   +9 more
doaj   +1 more source

Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer [PDF]

British Journal of Cancer, 2013
The host immune reaction is represented by immune/inflammatory cell infiltrates. Here we systematically analysed tumour-infiltrating immune/inflammatory cells in pancreatic ductal carcinoma (PDC) and evaluated their clinicopathological impact.Using immunohistochemistry, we examined tumour-infiltrating CD68(+) pan-macrophages, HLA-DR(+)CD68(+) M1 ...
Ino, Y, Yamazaki-Itoh, R, Shimada, K, Iwasaki, M, Kosuge, T, Kanai, Y, Hiraoka, N   +6 more
openaire   +2 more sources

Characterization of Immune-Related Genes and Immune Infiltration Features in Epilepsy by Multi-Transcriptome Data

Journal of Inflammation Research, 2022
Yunqi Hou,1,* Zhen Chen,2,* Liping Wang,3 Yingxin Deng,1 Genglong Liu,4 Yongfen Zhou,1 Haiqin Shi,1 Xiangqun Shi,1 Qianhua Jiang2 1Department of Neurology, Shunde Hospital, Southern Medical University (The First People’s Hospital of Shunde ...
Hou Y, Chen Z, Wang L, Deng Y, Liu G, Zhou Y, Shi H, Shi X, Jiang Q   +8 more
doaj  

Identification of immune infiltration-related genes as prognostic indicators for hepatocellular carcinoma

BMC Cancer, 2022
Hepatocellular carcinoma (HCC) has a high degree of malignancy and a poor prognosis. Immune infiltration-related genes have shown good predictive value in the prognosis of many solid tumours.
Kunfu Dai, Chao Liu, Ge Guan, Jinzhen Cai, Liqun Wu   +4 more
doaj   +1 more source

TIMER2.0 for analysis of tumor-infiltrating immune cells [PDF]

Nucleic Acids Research, 2020
Abstract Tumor progression and the efficacy of immunotherapy are strongly influenced by the composition and abundance of immune cells in the tumor microenvironment. Due to the limitations of direct measurement methods, computational algorithms are often used to infer immune cell composition from bulk tumor transcriptome profiles.
Taiwen Li, Jingxin Fu, Zexian Zeng, David Cohen, Jing Li, Qianming Chen, Bo Li, Xiaole Shirley Liu   +7 more
openaire   +2 more sources

Correlation analysis between immune-related genes and cell infiltration revealed prostate cancer immunotherapy biomarkers linked to T cells gamma delta

Scientific Reports, 2023
Prostate cancer (PCa) is a urological malignancy with poor prognosis. Immune-related genes are associated with immune infiltration in prostate cancer, but their role in immunogenic PCa is less well understood.
Wenkang Niu, Tingting Zhang, Lei Ma
doaj   +1 more source

Immune infiltration analysis data between APC expression and immune infiltration.

, 2022
The heat maps and scatter plots of immune infiltration analysis data between APC expression and immune infiltration were displayed. The P-value and cor were supplied.
Xiaolong Tang (442900), Yinci Zhang (5417780), Amin Li (1960315), Xinkuang Liu (5417789)   +3 more
core   +1 more source

Immune signature of tumor infiltrating immune cells in renal cancer [PDF]

OncoImmunology, 2015
Tumor-associated immune cells have been discussed as an essential factor for the prediction of the outcome of tumor patients. Lymphocyte-specific genes are associated with a favorable prognosis in colorectal cancer but with poor survival in renal cell carcinoma (RCC).
Katharina, Geissler, Paolo, Fornara, Christine, Lautenschläger, Hans-Jürgen, Holzhausen, Barbara, Seliger, Dagmar, Riemann   +5 more
openaire   +2 more sources

Association of SMC4 with prognosis and immune infiltration of sarcoma

Aging, 2023
This study was performed to explore the prognostic relevance of structural maintenance of chromosomes 4 (SMC4) in pan-cancer and explore the association between SMC4 and immune infiltration of sarcoma.Elevated expression of SMC4 was detected in cancer tissues compared to normal tissue, which was confirmed in synovial sarcoma tissues with ...
Jiang, Guangyao, Chen, Junjie, Li, Yan, Zhou, Jian, Wang, Wanchun, Wu, Gen, Zhang, Yupeng   +6 more
openaire   +2 more sources

Immune Landscape of Invasive Ductal Carcinoma Tumor Microenvironment Identifies a Prognostic and Immunotherapeutically Relevant Gene Signature

Frontiers in Oncology, 2019
Background: Invasive ductal carcinoma (IDC) is a clinically and molecularly distinct disease. Tumor microenvironment (TME) immune phenotypes play crucial roles in predicting clinical outcomes and therapeutic efficacy.Method: In this study, we depict the ...
Xuanwen Bao, Xuanwen Bao, Run Shi, Kai Zhang, Shan Xin, Xin Li, Yanbo Zhao, Yanfang Wang   +7 more
doaj   +1 more source