Results 21 to 30 of about 1,707,239 (310)

Exploration of the Immune-Related Signatures and Immune Infiltration Analysis in Melanoma [PDF]

open access: yesAnalytical Cellular Pathology, 2021
In the present study, we aimed to investigate immune-related signatures and immune infiltration in melanoma. The transcriptome profiling and clinical data of melanoma were downloaded from The Cancer Genome Atlas database, and their matched normal samples were obtained from the Genotype-Tissue Expression database.
Ai-lan Li   +8 more
openaire   +3 more sources

Immune infiltration in renal cell carcinoma [PDF]

open access: yesCancer Science, 2019
Immune infiltration of tumors is closely associated with clinical outcome in renal cell carcinoma (RCC). Tumor‐infiltrating immune cells (TIICs) regulate cancer progression and are appealing therapeutic targets. The purpose of this study was to determine the composition of TIICs in RCC and further reveal the independent prognostic values of TIICs ...
Shichao Zhang   +9 more
openaire   +2 more sources

Immune infiltration and immunophenotyping in atrial fibrillation

open access: yesAging, 2023
الرجفان الأذيني هو اضطراب نظم شائع نسبيًا في الممارسة السريرية. على الرغم من إحراز تقدم كبير في علاج الرجفان الأذيني والمضاعفات المرتبطة به، إلا أن الأبحاث حول الوقاية من الرجفان الأذيني متخلفة، ويرجع ذلك أساسًا إلى عدم وجود فهم عميق للتسبب في الرجفان الأذيني.
Yuqing Tian   +7 more
openaire   +2 more sources

Identification and Validation of Immune Infiltration Phenotypes in Laryngeal Squamous Cell Carcinoma by Integrative Multi-Omics Analysis

open access: yesFrontiers in Immunology, 2022
BackgroundLaryngeal squamous cell carcinoma (LSCC) is one of the world’s most common head and neck cancer. However, the immune infiltration phenotypes of LSCC have not been well investigated.MethodsThe multi-omics data of LSCC were obtained from the TCGA
Li Yan   +5 more
doaj   +1 more source

Immune Cell Infiltrate and Prognosis in Gastric Cancer [PDF]

open access: yesCancers, 2020
Purpose: To examine and compare the prognostic value of immune cell score (ICS) and Klintrup–Mäkinen (KM) grade in gastric cancer. Methods: Gastric adenocarcinoma tissues from samples of 741 patients surgically treated in two hospitals in Finland were assessed for ICS and KM grade.
Niko Kemi   +11 more
openaire   +3 more sources

Spatially variant immune infiltration scoring in human cancer tissues

open access: yesnpj Precision Oncology, 2022
The Immunoscore is a method to quantify the immune cell infiltration within cancers to predict the disease prognosis. Previous immune profiling approaches relied on limited immune markers to establish patients’ tumor immunity.
Mayar Allam   +9 more
doaj   +1 more source

Tumor Immunometabolism Characterization in Ovarian Cancer With Prognostic and Therapeutic Implications

open access: yesFrontiers in Oncology, 2021
Metabolic dysregulation in the tumor microenvironment has significant impact on immune infiltration and immune responses. However, interaction between immunity and metabolism in the ovarian microenvironment requires further exploration. We constructed an
Miner Yang   +3 more
doaj   +1 more source

Infiltration of tumor spheroids by activated immune cells

open access: yesPhysical Biology, 2022
Abstract Recent years have seen a tremendous growth of interest in understanding the role that the adaptive immune system could play in interdicting tumor progression. In this context, it has been shown that the density of adaptive immune cells inside a solid tumor serves as a favorable prognostic marker across different types of ...
Mrinmoy Mukherjee   +5 more
openaire   +4 more sources

DFNA5 regulates immune cells infiltration and exhaustion [PDF]

open access: yesCancer Cell International, 2022
Abstract Background DFNA5 (GSDME) belongs to Gasdermin familily that is involved in a variety of cancers and triggers cell pyroptosis after chemical treatment. However, the relationship in DFNA5 between prognosis and immune cells in diverse cancers has been receiving little attention.
Jian Hu   +7 more
openaire   +3 more sources

Identification and Verification of Immune-Related Gene Prognostic Signature Based on ssGSEA for Osteosarcoma

open access: yesFrontiers in Oncology, 2020
Osteosarcoma is the most common malignant bone tumor in children and adolescence. Multiple immune-related genes have been reported in different cancers.
Bo Xiao   +13 more
doaj   +1 more source

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