Results 11 to 20 of about 2,850,822 (303)
Immune Microenvironment of Thyroid Cancer [PDF]
Journal of Cancer, 2020 Thyroid cancer (TC) is a highly heterogeneous endocrine malignancy with an increased incidence in women than in men. Previous studies regarding the pathogenesis of TC focused on the pathological changes of the tumor cells while ignoring the importance of the mesenchymal cells in tumor microenvironment.
Hongyu Yin +3 more
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Tumor immune microenvironment lncRNAs [PDF]
Briefings in Bioinformatics, 2021 AbstractLong non-coding ribonucleic acids (RNAs) (lncRNAs) are key players in tumorigenesis and immune responses. The nature of their cell type-specific gene expression and other functional evidence support the idea that lncRNAs have distinct cellular functions in the tumor immune microenvironment (TIME).
Eun-Gyeong Park +4 more
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Immune microenvironment of gliomas [PDF]
Laboratory Investigation, 2017 High-grade gliomas are rapidly progressing tumors of the central nervous system (CNS) with a very poor prognosis despite extensive resection combined with radiation and/or chemotherapy. Histopathological and flow cytometry analyses of human and rodent experimental gliomas revealed heterogeneity of a tumor and its niche, composed of reactive astrocytes,
Gieryng, Anna +4 more
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Immune response in glioma’s microenvironment [PDF]
Innovative Surgical Sciences, 2020 Abstract Objectives Glioma is the most common tumor of the central nervous system. In this review, we outline the immunobiological factors that interact with glioma cells and tumor microenvironment (TME), providing more potential targets for clinical inhibition of glioma development and more ...
Chen Houminji +6 more
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The Immune Microenvironment of Myeloma [PDF]
Cancer Microenvironment, 2011 The bone marrow (BM) is the site of disease in myeloma and possesses unique immune characteristics involved in the pathobiology of the disease. Interactions of plasma cells with stromal cells, osteoclasts, osteoblasts, myeloid and lymphoid cells make up the unique bone marrow milieu that mediates myeloma disease progression.
Kimberly, Noonan, Ivan, Borrello
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The immune microenvironment in gastric adenocarcinoma
Nature Reviews Gastroenterology & Hepatology, 2022 Like most solid tumours, the microenvironment of epithelial-derived gastric adenocarcinoma (GAC) consists of a variety of stromal cell types, including fibroblasts, and neuronal, endothelial and immune cells. In this article, we review the role of the immune microenvironment in the progression of chronic inflammation to GAC, primarily the immune ...
Y. Zavros, J. Merchant
semanticscholar +3 more sources
mBio, 2022 Urinary tract infections (UTIs) are a global public health concern, which is mainly caused by uropathogenic Escherichia coli (UPEC). Cytotoxic necrotizing factor 1 (CNF1) is a key UPEC toxin and regulates multiple host cellular processes through ...
Xuan Sun +13 more
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Identification of novel immune subtypes and potential hub genes of patients with psoriasis
Journal of Translational Medicine, 2023 Background Psoriasis is a common, chronic and relapsing immune-related inflammatory dermal disease. Patients with psoriasis suffering from the recurrences is mainly caused by immune response disorder.
Yingxi Li +8 more
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Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock
Frontiers in Immunology, 2021 Pin1 is the only known peptidyl-prolyl cis-trans isomerase (PPIase) that can specifically recognize and isomerize the phosphorylated Serine/Threonine-Proline (pSer/Thr-Pro) motif, change the conformation of proteins through protein phosphorylation, thus ...
Ruijie Dong +6 more
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Immune Microenvironment in Glioblastoma Subtypes [PDF]
Frontiers in Immunology, 2018 Glioblastomas (GBMs) are the most common and aggressive primary brain tumors. Due to their malignant growth and invasion into the brain parenchyma coupled with resistance to therapy, GBMs are among the deadliest of all cancers. GBMs are highly heterogeneous at both the molecular and histological levels.
Zhihong Chen, Dolores Hambardzumyan
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