Results 11 to 20 of about 1,580,087 (314)
In the eye of the storm: T cell behavior in the inflammatory microenvironment. [PDF]
, 2013 Coordinated unfolding of innate and adaptive immunity is key to the development of protective immune responses. This functional integration occurs within the inflamed tissue, a microenvironment enriched with factors released by innate and subsequently ...
Marelli-Berg, F +5 more
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Tumor immune microenvironment lncRNAs [PDF]
Briefings in Bioinformatics, 2021 AbstractLong non-coding ribonucleic acids (RNAs) (lncRNAs) are key players in tumorigenesis and immune responses. The nature of their cell type-specific gene expression and other functional evidence support the idea that lncRNAs have distinct cellular functions in the tumor immune microenvironment (TIME).
Eun-Gyeong Park +4 more
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Immune microenvironment of gliomas [PDF]
Laboratory Investigation, 2017 High-grade gliomas are rapidly progressing tumors of the central nervous system (CNS) with a very poor prognosis despite extensive resection combined with radiation and/or chemotherapy. Histopathological and flow cytometry analyses of human and rodent experimental gliomas revealed heterogeneity of a tumor and its niche, composed of reactive astrocytes,
Gieryng, Anna +4 more
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Immune Microenvironment of Thyroid Cancer [PDF]
Journal of Cancer, 2020 Thyroid cancer (TC) is a highly heterogeneous endocrine malignancy with an increased incidence in women than in men. Previous studies regarding the pathogenesis of TC focused on the pathological changes of the tumor cells while ignoring the importance of the mesenchymal cells in tumor microenvironment.
Yin, Hongyu +3 more
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The Immune Microenvironment of Myeloma [PDF]
Cancer Microenvironment, 2011 The bone marrow (BM) is the site of disease in myeloma and possesses unique immune characteristics involved in the pathobiology of the disease. Interactions of plasma cells with stromal cells, osteoclasts, osteoblasts, myeloid and lymphoid cells make up the unique bone marrow milieu that mediates myeloma disease progression.
Kimberly, Noonan, Ivan, Borrello
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Immune response in glioma’s microenvironment [PDF]
Innovative Surgical Sciences, 2020 Abstract Objectives Glioma is the most common tumor of the central nervous system. In this review, we outline the immunobiological factors that interact with glioma cells and tumor microenvironment (TME), providing more potential targets for clinical inhibition of glioma development and more ...
Chen Houminji +6 more
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Immune Microenvironment in Glioblastoma Subtypes [PDF]
Frontiers in Immunology, 2018 Glioblastomas (GBMs) are the most common and aggressive primary brain tumors. Due to their malignant growth and invasion into the brain parenchyma coupled with resistance to therapy, GBMs are among the deadliest of all cancers. GBMs are highly heterogeneous at both the molecular and histological levels.
Zhihong Chen, Dolores Hambardzumyan
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The Immune Microenvironment in Pancreatic Cancer [PDF]
International Journal of Molecular Sciences, 2020 The biology of solid tumors is strongly determined by the interactions of cancer cells with their surrounding microenvironment. In this regard, pancreatic cancer (pancreatic ductal adenocarcinoma, PDAC) represents a paradigmatic example for the multitude of possible tumor–stroma interactions.
Magdalena Huber +9 more
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Immune Microenvironment in Hematologic Malignancies.
Iranian journal of medical sciences, 2023 The role of the tumor microenvironment (TME), especially immune cell compartments, in tumor progression is inevitable and the heterogeneity and complexity of the TME-associated immune cells make it challenging to provide appropriate treatments for hematologic malignancies.
Arandi, Nargess, Dehghani, Mehdi
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Engineering the tumor microenvironment of colorectal cancer [PDF]
, 2014 The tumor microenvironment contributes significantly to the clinical prognosis, especially in CRC. Infiltration by cells from the adaptive immune system (e.g. CD8) has been linked to a better survival independently of TNM-stage.
Hirt, Christian Kurt
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