Results 11 to 20 of about 465,229 (318)
Immune Microenvironment of Thyroid Cancer [PDF]
Thyroid cancer (TC) is a highly heterogeneous endocrine malignancy with an increased incidence in women than in men. Previous studies regarding the pathogenesis of TC focused on the pathological changes of the tumor cells while ignoring the importance of the mesenchymal cells in tumor microenvironment.
Yin, Hongyu +3 more
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Immune response in glioma’s microenvironment [PDF]
Abstract Objectives Glioma is the most common tumor of the central nervous system. In this review, we outline the immunobiological factors that interact with glioma cells and tumor microenvironment (TME), providing more potential targets for clinical inhibition of glioma development and more ...
Chen Houminji +6 more
openaire +3 more sources
B cells, which consist of two well-defined populations: B1 and B2 cells, which can produce antibodies that are essential for host protection against infections, through virus neutralization, opsonization and antibody-dependent cellular cytotoxicity ...
Sulan Zhai +10 more
doaj +1 more source
The Immune Microenvironment of Malignant Pleural Mesothelioma: A Literature Review [PDF]
Malignant pleural mesothelioma (MPM) is a rare and aggressive tumour with a poor prognosis, associated with asbestos exposure. Nowadays, treatment is based on chemotherapy with a median overall survival of less than two years.
Anne-Laure Désage +3 more
core +1 more source
Background Chronic stress promotes most hallmarks of cancer through impacting the malignant tissues, their microenvironment, immunity, lymphatic flow, etc.
Jun Pan +12 more
doaj +1 more source
Immune Cells in the Tumor Microenvironment of Soft Tissue Sarcomas [PDF]
Soft tissue sarcomas (STSs) are a rare heterogeneous group of malignant neoplasms characterized by their aggressive course and poor response to treatment. This determines the relevance of research aimed at studying the pathogenesis of STSs. By now, it is
Timur Fatkhudinov +4 more
core +1 more source
Immune microenvironment of gliomas [PDF]
High-grade gliomas are rapidly progressing tumors of the central nervous system (CNS) with a very poor prognosis despite extensive resection combined with radiation and/or chemotherapy. Histopathological and flow cytometry analyses of human and rodent experimental gliomas revealed heterogeneity of a tumor and its niche, composed of reactive astrocytes,
Gieryng, Anna +4 more
openaire +2 more sources
Tumor immune microenvironment lncRNAs [PDF]
AbstractLong non-coding ribonucleic acids (RNAs) (lncRNAs) are key players in tumorigenesis and immune responses. The nature of their cell type-specific gene expression and other functional evidence support the idea that lncRNAs have distinct cellular functions in the tumor immune microenvironment (TIME).
Eun-Gyeong Park +4 more
openaire +2 more sources
Chlamydia trachomatis usually causes mucosal infections, bringing considerable morbidity and socioeconomic burden worldwide. We previously revealed that IL-27/IL-27R mediates protection against chlamydial invasion by promoting a protective Th1 response ...
Jiajia Zeng +9 more
doaj +1 more source
The Immune Microenvironment of Myeloma [PDF]
The bone marrow (BM) is the site of disease in myeloma and possesses unique immune characteristics involved in the pathobiology of the disease. Interactions of plasma cells with stromal cells, osteoclasts, osteoblasts, myeloid and lymphoid cells make up the unique bone marrow milieu that mediates myeloma disease progression.
Kimberly, Noonan, Ivan, Borrello
openaire +2 more sources

