Results 31 to 40 of about 2,850,822 (303)
Role of Intra- and Extracellular Lipid Signals in Cancer Stemness and Potential Therapeutic Strategy
Frontiers in Pharmacology, 2021 Accumulating evidence showed that cancer stem cells (CSCs) play significant roles in cancer initiation, resistance to therapy, recurrence and metastasis. Cancer stem cells possess the ability of self-renewal and can initiate tumor growth and avoid lethal
Jianming Hu +13 more
doaj +1 more source
The ambitious role of anti angiogenesis molecules: Turning a cold tumor into a hot one [PDF]
, 2018 In renal cancer emerging treatment options are becoming available and there is a strong need to combine therapies to reformulate and adjourn clinical practice.
Botticelli, A. +4 more
core +1 more source
Military Medical Research, 2022 Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting a variety of cell types, whose activity and interplay must be precisely mediated for effective healing post-injury.
Y. Xiong +13 more
semanticscholar +1 more source
Peritoneal immune microenvironment of endometriosis: Role and therapeutic perspectives
Frontiers in Immunology, 2023 Endometriosis, an estrogen-dependent chronic inflammatory disease characterized by the growth of endometrium-like tissues outside the uterine cavity, affects 10% of reproductive-age women.
Siman Chen +5 more
semanticscholar +1 more source
Immunological backbone of uveal melanoma: is there a rationale for immunotherapy? [PDF]
, 2019 No standard treatment has been established for metastatic uveal melanoma (mUM). Immunotherapy is commonly used for this disease even though UM has not been included in phase III clinical trials with checkpoint inhibitors.
Alessandra Cassano +24 more
core +1 more source
Advancement of science, 2022 Tumor immunotherapy is only effective in a fraction of patients due to a low response rate and severe side effects, and these challenges of immunotherapy in clinics can be addressed through induction of immunogenic cell death (ICD).
Zhilin Li +8 more
semanticscholar +1 more source
The immune microenvironment of the hydatidiform mole
Human Pathology, 2022 Gestational trophoblastic diseases (GTDs) are a heterogeneous group of lesions, the most frequent being the hydatidiform mole (HM). HMs are usually cured after surgical treatment or after chemotherapy in the case of a persistent trophoblastic activity. Immunotherapy could be an interesting alternative as a first-line or second-line treatment.
Maroa Dridi +7 more
openaire +3 more sources
The Immune Microenvironment in Pancreatic Cancer [PDF]
International Journal of Molecular Sciences, 2020 The biology of solid tumors is strongly determined by the interactions of cancer cells with their surrounding microenvironment. In this regard, pancreatic cancer (pancreatic ductal adenocarcinoma, PDAC) represents a paradigmatic example for the multitude of possible tumor–stroma interactions.
Magdalena Huber +9 more
openaire +2 more sources
Drosophila as a model system to study nonautonomous mechanisms affecting tumour growth and cell death [PDF]
, 2018 The study of cancer has represented a central focus in medical research for over a century. The great complexity and constant evolution of the pathology require the use of multiple research model systems and interdisciplinary approaches.
Cordero, Julia B. +2 more
core +7 more sources
FGF9 Alleviates the Fatty Liver Phenotype by Regulating Hepatic Lipid Metabolism
Frontiers in Pharmacology, 2022 Although the fatty liver has been linked to numerous impairments of energy homeostasis, the molecular mechanism responsible for fatty liver development remains largely unknown.
Fanrong Zhao +5 more
doaj +1 more source