Results 51 to 60 of about 2,850,822 (303)
Advances in Materials, 2023 Injectable hydrogels carrying therapeutic factors to modulate the infarct immune microenvironment show great potential in the treatment of myocardial infarction (MI).
Wei Chen +9 more
semanticscholar +1 more source
Activated lymphocyte recruitment into the tumor microenvironment following preoperative sipuleucel-T for localized prostate cancer. [PDF]
, 2014 BackgroundSipuleucel-T is a US Food and Drug Administration-approved immunotherapy for asymptomatic or minimally symptomatic metastatic castration-resistant prostate cancer (mCRPC). Its mechanism of action is not fully understood.
Amling, Christopher L +12 more
core +2 more sources
Tumor Immune Microenvironment and Immunosuppressive Therapy in Hepatocellular Carcinoma: A Review
International Journal of Molecular Sciences, 2021 Liver cancer has the fourth highest mortality rate of all cancers worldwide, with hepatocellular carcinoma (HCC) being the most prevalent subtype. Despite great advances in systemic therapy, such as molecular-targeted agents, HCC has one of the worst ...
K. Oura +3 more
semanticscholar +1 more source
Scientific Reports, 2017 Adiponectin (APN), also known as apM1, Acrp30, GBP28 and adipoQ, is a circulating hormone that is predominantly produced by adipose tissue. Many pharmacological studies have demonstrated that this protein possesses potent anti-diabetic, anti-atherogenic ...
Yinghui Ren +14 more
doaj +1 more source
Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model. [PDF]
, 2017 BackgroundToca 511 (vocimagene amiretrorepvec) is a retroviral replicating vector encoding an optimized yeast cytosine deaminase (CD). Tumor-selective expression of CD converts the prodrug, 5-fluorocytosine (5-FC), into the active chemotherapeutic, 5 ...
Gruber, Harry E +9 more
core +1 more source
Molecular Cancer, 2023 N6-methyladenosine (m^6A) methylation is the most universal internal modification in eukaryotic mRNA. With elaborate functions executed by m^6A writers, erasers, and readers, m^6A modulation is involved in myriad physiological and pathological processes.
Xiaoxue Cao +12 more
semanticscholar +1 more source
Neural regulation of cancer: from mechanobiology to inflammation. [PDF]
, 2016 Despite recent progress in cancer research, the exact nature of malignant transformation and its progression is still not fully understood. Particularly metastasis, which accounts for most cancer death, is a very complex process, and new treatment ...
Kim, Tae-Hyung +2 more
core +5 more sources
Immunoregulatory Potential of Exosomes Derived from Cancer Stem Cells. [PDF]
, 2020 Head and neck squamous cell carcinomas (HNSCCs) are malignancies that originate in the mucosal lining of the upper aerodigestive tract. Despite advances in therapeutic interventions, survival rates among HNSCC patients have remained static for years ...
Abouyared, Marianne +10 more
core +1 more source
The Tumor Immune Microenvironment in Clear Cell Renal Cell Carcinoma
International Journal of Molecular Sciences, 2023 Clear cell renal cell carcinoma (ccRCC) is a type of kidney cancer that arises from the cells lining the tubes of the kidney. The tumor immune microenvironment (TIME) of ccRCC is a complex interplay of various immune cells, cytokines, and signaling ...
Cesar U. Monjaras-Avila +5 more
semanticscholar +1 more source
The Immune Microenvironment and Cancer Metastasis [PDF]
Cold Spring Harbor Perspectives in Medicine, 2019 The dynamic interplay between neoplastic cells and the immune microenvironment regulates every step of the metastatic process. Immune cells contribute to invasion by secreting a cornucopia of inflammatory factors that promote epithelial-to-mesenchymal transition and remodeling of the stroma.
Asmaa, El-Kenawi +2 more
openaire +2 more sources