Results 51 to 60 of about 465,229 (318)
The Landscape and Clinical Application of the Tumor Microenvironment in Gastroenteropancreatic Neuroendocrine Neoplasms [PDF]
, 2022 SIMPLE SUMMARY: The tumor microenvironment (TME) plays a role in promoting tumor progression. Elucidating the relationship between the TME and tumor cells will benefit current therapies.
Chen, Ruyin +9 more
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C9orf16 represents the aberrant genetic programs and drives the progression of PDAC
BMC Cancer, 2022 Background Pancreatic ductal adenocarcinoma (PDAC), constituting 90% of pancreatic cancers, is the fourth leading cause of cancer-related deaths in the world.
Xiaojun Chen, Hong Zhang, Bo Xiao
doaj +1 more source
Immune cells within the tumor microenvironment [PDF]
, 2013 A plethora of intrinsic and extrinsic factors, including communication between tumorigenic cells and infiltrating immune cells, fibroblasts, epithelial cells, vascular and lymphatic endothelial cells, cytokines and chemokines, constitute the tumor ...
ZOLLO, MASSIMO +3 more
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The Three-Dimensional In Vitro Cell Culture Models in the Study of Oral Cancer Immune Microenvironment [PDF]
, 2023 The onset and progression of oral cancer are accompanied by a dynamic interaction with the host immune system, and the immune cells within the tumor microenvironment play a pivotal role in the development of the tumor.
Elaheh Dalir Abdolahinia, Xiaozhe Han
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Cancer Medicine, 2023 Background PRDM5 is considered a tumor suppressor in several types of solid tumors and is involved in multiple cellular processes. However, target genes regulated by PRDM5 in lung cancer and its potential mechanism are poorly defined.
Yuanyuan Ren +9 more
doaj +1 more source
CXCL8 Up-Regulated LSECtin through AKT Signal and Correlates with the Immune Microenvironment Modulation in Colon Cancer [PDF]
, 2022 Background: The role of CXCL8 and LSECtin in colon cancer liver metastasis and immune checkpoint inhibitors (ICIs) treatment effect were widely recognized. However, the regulatory role of CXCL8 on LSECtin is still unclear.
Jian Dong +21 more
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Pyroptosis, metabolism, and tumor immune microenvironment [PDF]
Clinical and Translational Medicine, 2021 AbstractIn response to a wide range of stimulations, host cells activate pyroptosis, a kind of inflammatory cell death which is provoked by the cytosolic sensing of danger signals and pathogen infection. In manipulating the cleavage of gasdermins (GSDMs), researchers have found that GSDM proteins serve as the real executors and the deterministic ...
Tiantian Du +8 more
openaire +3 more sources
Tumor Immune Microenvironment in Lymphoma: Focus on Epigenetics [PDF]
, 2022 Lymphoma is a neoplasm arising from B or T lymphocytes or natural killer cells characterized by clonal lymphoproliferation. This tumor comprises a diverse and heterogeneous group of malignancies with distinct clinical, histopathological, and molecular ...
Daniel J. García-Domínguez +17 more
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Metabolites and Immune Response in Tumor Microenvironments [PDF]
, 2023 The remodeled cancer cell metabolism affects the tumor microenvironment and promotes an immunosuppressive state by changing the levels of macro- and micronutrients and by releasing hormones and cytokines that recruit immunosuppressive immune cells. Novel
Salvatore Cortellino, Valter D. Longo
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Vascular Microenvironment, Tumor Immunity and Immunotherapy [PDF]
Frontiers in Immunology, 2021 Immunotherapy holds great promise for treating cancer. Nonetheless, T cell-based immunotherapy of solid tumors has remained challenging, largely due to the lack of universal tumor-specific antigens and an immunosuppressive tumor microenvironment (TME) that inhibits lymphocyte infiltration and activation.
Zachary Lamplugh, Yi Fan
openaire +3 more sources