Results 101 to 110 of about 1,217,623 (290)
The origin of non-specific effects of vaccines and the role of randomised clinical trials
Human Vaccines & ImmunotherapeuticsRecent articles claim that randomized clinical trials (RCTs) have not documented non-specific effects of vaccines (NSE), i.e. broader immunomodulatory effects of vaccines. We reviewed the role of RCTs in the discovery of NSEs.
Christine S. Benn +3 more
doaj +1 more source
Force feedback linearization for higher-order electromechanical sigma-delta modulators.
, 2006 A higher-order electromechanical sigma–delta modulator can greatly improve the signal-to-noise ratio compared with a second-order loop that only uses the sensing element as a loop filter.
Redman-White, William +2 more
core
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
The role of basophils as innate immune regulatory cells in allergy and immunotherapy
Human Vaccines & Immunotherapeutics, 2018 Basophils are circulating cells that are associated quite exclusively with allergy response and hypersensitivity reactions but their role in the immune network might be much more intriguing and complex than previously expected. The feasibility of testing
Salvatore Chirumbolo +3 more
doaj +1 more source
Artificial Immune Systems - Models, algorithms and applications [PDF]
, 2010 Copyright © 2010 Academic Research Publishing Agency.This article has been made available through the Brunel Open Access Publishing Fund.Artificial Immune Systems (AIS) are computational paradigms that belong to the computational intelligence family and ...
Alsharhan, S, Al-Enezi, JR, Abbod, MF
core +3 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CD28 Aptamers as Powerful Immune Response Modulators
Molecular Therapy: Nucleic Acids, 2013 CD28 is one of the main costimulatory receptors responsible for the proper activation of T lymphocytes. We have isolated two aptamers that bind to the CD28 receptor.
Fernando Pastor +10 more
doaj +1 more source
Towards Immune Inspired Fault Tolerance in Embedded Systems [PDF]
, 2002 The immune system is a remarkable natural system that is proving to be of great inspiration to computer scientists and engineers alike. This paper discusses the role that the immune system can play in the development of fault tolerant embedded systems ...
Timmis, Jon +3 more
core +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Therapeutic possibilities in treatment of cervical pathology in patients with HPV-infection [PDF]
Гинекология, 2015 The article provides an overview of the scientific data on the effectiveness of Polyoxidonium® in gynecological practice with the influence of the drug on the local and systemic immunity and effectiveness in the treatment of inflammatory diseases of the ...
E A Chulkova, O V Chulkova
doaj