Results 171 to 180 of about 78,926 (342)

Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation

Experimental Physiology, EarlyView.
Abstract Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS inflammation.
Mehrdad Nourizadeh, Amir Arsalan Ghahari, Ehsan Zandi, Seyedeh Zeynab Rasouli, Shaghayegh Davari, Mobina Hoseinzadeh, Mir Alireza Nourazar   +6 more
wiley   +1 more source

Current Trends in Duchenne Muscular Dystrophy Research and Therapy: 3D Cardiac Modelling

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Duchenne muscular dystrophy (DMD), caused by dystrophin deficiency, presents a multifaceted challenge that affects both skeletal muscle function and cardiomyocyte homeostasis, causing progressive degeneration and life‐threatening cardiac complications by adolescence.
Marta Przymuszała, Marta Białobrzeska, Józef Dulak, Urszula Florczyk‐Soluch   +3 more
wiley   +1 more source

Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings

, 2020
Graeme Meintjes, Stephen D Lawn, Fabio Scano, Gary Maartens, Martyn A. French, William Worodria, Julian Elliott, David R. Murdoch, Robert J. Wilkinson, Catherine Seyler, Laurence John, Maarten Schim van der Loeff, Peter Reiss, Lutgarde Lynen, Edward N. Janoff, Charles F. Gilks, Robert Colebunders   +16 more
openalex   +1 more source

Hemophagocytic Lymphohistiocytosis as First Manifestation of Dual B‐Cell Neoplasms: A Case Report of Co‐Existing Multiple Myeloma and B‐Cell Lymphoma

eJHaem, Volume 7, Issue 1, February 2026.
ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is an immune disorder causing excessive inflammation and tissue damage. Lymphoma, especially T‐cell lymphoma, is the most common cause of HLH, while Multiple Myeloma (MM) is rarely associated. We present a 61‐year‐old man with spiking fevers, fatigue, and unintentional weight loss. The HLH was driven by
Carla Romagnoli, Alexandra Lyubimova, Leily Santos‐Carrion, Ferial Alloush, Vathany Sriganeshan, Andrea Noboa, Jacqueline C. Barrientos   +6 more
wiley   +1 more source

Construction of Reverse Genetics System for Feline Calicivirus FCV‐BJ616 and Proteomic Analysis

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
This study successfully isolated the FCV‐BJ616 strain derived from cats and established a reverse genetics system. In vivo experiments showed that rFCV‐BJ616 exhibits wild‐type virulence, leading to high fever, weight loss, and multi‐organ lesions in infected cats. Proteomic analysis indicated that both rFCV‐BJ616 and FCV‐BJ616 share similar regulatory
Chunmei Xu, Jingjie Zhao, Hao Liu, Haotian Gu, Xinming Tang, Lin Liang, Jiabo Ding, Shaohua Hou, Xiaomin Zhao, Ruiying Liang   +9 more
wiley   +1 more source

Matrix metalloproteinases and tissue damage in HIV‐tuberculosis immune reconstitution inflammatory syndrome [PDF]

, 2013
Rebecca Tadokera, Graeme Meintjes, Katalin A. Wilkinson, Keira Skolimowska, Naomi F. Walker, Jon S. Friedland, Gary Maartens, Paul Elkington, Robert J. Wilkinson   +8 more
openalex   +1 more source

Immune reconstitution inflammatory syndrome

Indian Journal of Dermatology, Venereology and Leprology, 2006
A U, Surjushe, S R, Jindal, R R, Kamath, D G, Saple   +3 more
openaire   +2 more sources

Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications

MedComm, Volume 7, Issue 2, February 2026.
The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin, Minying Xiong, Aimin Jiang, Li Chen, Lihaoyun Huang, Kailai Li, Hank Z. H. Wong, Jian Zhang, Zaoqu Liu, Quan Cheng, Bufu Tang, Pengpeng Zhang, Peng Luo   +12 more
wiley   +1 more source

Incidence of immune reconstitution inflammatory syndrome among HIV patients infected with tuberculosis in a Dublin cohort [PDF]

, 2008
EG Muldoon, MC Mokoka, Petra Kok, Cora McNally   +3 more
openalex   +1 more source

A Scalable Organoid Model of Urothelial Aging for Metabolic Interrogation, Infection Modeling, and Reversal of Age‐Associated Changes

Aging Cell, Volume 25, Issue 2, February 2026.
mBEDOs: a scalable platform for modeling urothelial aging. mBEDOs derived from aged mouse bladders capture essential molecular and cellular features of urothelial aging and provide a versatile system for high‐throughput metabolic profiling, therapeutic screening via metabolite supplementation, age‐ and sex‐based analyses, infection modeling, and immune–
Adwaita R. Parab, Arnold M. Salazar, Steven J. Bark, Margarita Divenko, Vasanta Putluri, D'Feau J. Lieu, Aadya S. Singh, Nagireddy Putluri, Indira U. Mysorekar   +8 more
wiley   +1 more source