Results 181 to 190 of about 78,926 (342)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

2 Tuberculosis-associated immune reconstitution inflammatory syndrome management

open access: yesClinical Infection in Practice, 2022
Diana David, Martin Dedicoat
doaj   +1 more source

Development of cytomegalovirus (CMV) immune recovery uveitis is associated with Th17 cell depletion and poor systemic CMV-specific T cell responses. [PDF]

open access: yes, 2011
Backgroundthe immune reconstitution inflammatory syndromes (IRIS) are a spectrum of inflammatory conditions associated with opportunistic infections and occurring in approximately16% of human immunodeficiency type 1 (HIV-1)-infected patients given ...
Hartigan-O'Connor, Dennis J   +4 more
core   +1 more source

Progressive Multifocal Leukoencephalopathy and Immune Reconstitution Inflammatory Syndrome after Discontinuation of Fingolimod

open access: gold, 2022
Raquel Piñar Morales   +3 more
openalex   +1 more source

Injectable Chitosan‐Platelet‐Rich Plasma Hybrid Biomaterial Improves Skin Wound Healing in Diabetic Rats

open access: yesAdvanced Therapeutics, Volume 9, Issue 1, January 2026.
A biomaterial combining fresh platelet‐rich plasma with freeze‐dried chitosan (CS‐PRP) enhances diabetic skin wound healing in rats. CS‐PRP accelerates closure over the course of a month, improves healing tissue architecture and collagen remodeling, and sustains vascularization.
Laura Ahunon   +5 more
wiley   +1 more source

Obesity‐Associated TRIM15 Promotes the Proliferation of Esophageal Adenocarcinoma Through the YY2/FOXRED1 Axis

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
The study identifies TRIM15 as a key driver in the development of obesity‐associated esophageal adenocarcinoma (EAC). Mechanistically, TRIM15 degrades YY2 through the proteasome pathway, suppressing FOXRED1 transcription and ultimately accelerating tumor proliferation.
Haohui Wang   +10 more
wiley   +1 more source

Faecalibaculum rodentium Alleviates Ionizing Radiation‐Induced Damage in Mice by Improving Intestinal Integrity and Hematopoiesis via Its Metabolite Butyrate

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
The model shows the probiotics screening and underlying mechanisms of F. rodentiumn in alleviating IR‐induced tissue injury. Stress‐induced STAT3 mitochondria localization decreases F. rodentium abundance and butyrate concentration. Supplementation of F.
Hanyong Zhu   +17 more
wiley   +1 more source

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

open access: yesAdvanced Science, Volume 13, Issue 6, 30 January 2026.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han   +10 more
wiley   +1 more source

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