Results 31 to 40 of about 43,379 (243)

The in silico macrophage: toward a better understanding of inflammatory disease [PDF]

Genome Medicine 2011, 3:4 (22 January 2011), 2011
Macrophages function as sentinel, cell-regulatory hubs capable of initiating, perpetuating and contributing to the resolution of an inflammatory response, following their activation from a resting state. Highly complex and varied gene expression programs within the macrophage enable such functional diversity.
arxiv   +1 more source

Interventions for neurocognitive dysfunction [PDF]

, 2017
Purpose of review: To evaluate current barriers to HIV cure strategies and interventions for neurocognitive dysfunction with a particular focus on recent advancements over the last three years. Recent findings: Optimal anti-retroviral therapy (ART) poses
Brew, B, Ellero, J, Lubomski, M
core   +2 more sources

Thymus transplantation for complete DiGeorge syndrome: European experience [PDF]

, 2017
Background: Thymus transplantation is a promising strategy for the treatment of athymic complete DiGeorge syndrome (cDGS). Methods: Twelve patients with cDGS were transplanted with allogeneic cultured thymus.
Adrian J. Thrasher, Alina Papadopol, Amrolia, Anderson, Anna Furmanski, Austen Worth, Blythe Devlin, David M. Sansom, Davies, Despina Moshous, E. Graham Davies, Elizabeth McCarthy, Furmanski, H. Bobby Gaspar, Hans Christian Erichsen, Hassan, Hassan, Heino, Ida Ricciardelli, Janda, Jesmeen Maimaris, Joe Curry, Jolanta Bernatoniene, Kathryn L. Parsley, Kim Neuling, Kimberly Gilmour, King, Konstantinos Mengrelis, Lizzie Hutchison, Luigi Poliani, M. Louise Markert, Malgorzata Pac, Marianne Ifversen, Markert, Markert, Markert, Markert, Markert, Markert, Markert, McGhee, Melissa Cheung, Michael Browning, Morbach, Morbach, Neil Halliday, Neil Sebire, Poliani, Ronald Bremner, Rucci, Ryan, Schubert, Shearer, Shearer, Stuart Adams, T. Ronan Leahy, Tessa Crompton, Tiia Voor, Winnie Ip, Yang   +59 more
core   +2 more sources

HIV-associated progressive multifocal leukoencephalopathy. Current perspectives [PDF]

, 2016
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system, caused by the polyomavirus JC and occurring almost exclusively in the context of severe immune depression.
Ciardi, M. R., D'Abramo, A., Iannetta, M., Mastroianni, C. M., Oliva, A., Vullo, V., Zingaropoli, M. A.   +6 more
core   +1 more source

Immune reconstitution inflammatory syndrome: A therapeutic paradox

Indian Dermatology Online Journal, 2012
A 41-year-old HIV positive woman was started on highly active antiretroviral therapy when her CD 4 count was 54/cu mm. Three weeks later, she developed erythematous to skin-colored plaques over the face.
Joan Felicita Samson, V Suja, K Abdul Samad, S Sankar, G K Libu   +4 more
doaj   +1 more source

Enhancing Innate and Adaptive Immune Systems by Cold Atmospheric Plasma (CAP) and Its Antitumor Immunity [PDF]

arXiv, 2022
Cold atmospheric plasma (CAP) is a near room temperature ionized gas, generated under non-equilibrium discharge conditions. Here we show that a short exposure of rat peritoneal exudate macrophages and T-cells to CAP in vitro, triggered an inflammatory phenotype leading to better antigen-presenting and effector cell function respectively. Different from
arxiv  

Augmenting adaptive immunity: progress and challenges in the quantitative engineering and analysis of adaptive immune receptor repertoires [PDF]

Mol. Syst. Des. Eng. (2019), 2019
The adaptive immune system is a natural diagnostic and therapeutic. It recognizes threats earlier than clinical symptoms manifest and neutralizes antigen with exquisite specificity. Recognition specificity and broad reactivity is enabled via adaptive B- and T-cell receptors: the immune receptor repertoire.
arxiv   +1 more source

Evolutionary biology and anthropology suggest biome reconstitution as a necessary approach toward dealing with immune disorders [PDF]

, 2013
Industrialized society currently faces a wide range of non-infectious, immune-related pandemics. These pandemics include a variety of autoimmune, inflammatory and allergic diseases that are often associated with common environmental triggers and with ...
Adler, Allen, Arbes, Backhed, Bagnasco, Bartlett, Becker, Becker, Bethell, Bickler, Bilbo, Bilbo, Black, Borkow, Brenner, Bronstein, Brown, Cannell, Capron, Casanova, Chandra, Correale, Correale, Dantzer, Davis, Day, de Borst, Devalapalli, Dominguez-Bello, Elliott, Fairweather, Fan, Fanaro, Fava, Feary, Feary, Feazel, Floch, Floch, Foliaki, Fumagalli, Gale, Gangoso, Gao, Genuis, Gernsbacher, Glaser, Gouin, Green, Grice, Guaraldi, Guarner, Guo, Hadley, Hanski, Hansson, Hare, Heck, Herre, Hewitson, Holick, Hummelen, Ippoliti, ISAAC Steering Committee, Isack, Jane Costello, Karst, Kelly, Kendall-Tackett, Khoruts, Kiecolt-Glaser, Kong, Krishnadas, Kronman, Lakhan, Leboyer, Lee, Lesher, Lin, Liu, Liu, Lowry, Lucas, Mackie, Malcolm, Mark, Mehta, Merrett, Meyer, Mills, Moylan, Nickens, Northrop-Clewes, Ollerton, Ollerton, Parker, Reiche, Rook, Rook, Rook, Rook, Rook, Ryder, Saha, Salim, Saunders, Sharief, Singh, Smith, Stojanovich, Strachan, Sullivan, Summers, Summers, Surawicz, Tilp, Trama, Turton, U.S. Food and Drug Administration, Valasquez-Manoff, van Nood, Vehik, von Hertzen, Waeber, Wang, Warren, Wilson, Wilson, Wohlleben, Wold, Yazdanbakhsh, Yoshioka, Zandman-Goddard, Zhou   +133 more
core   +1 more source

Paradoxical Immune Reconstitution Syndrome Presenting as Acute Respiratory Distress Syndrome in a Leukemia Patient during Neutrophil Recovery

Case Reports in Hematology, 2012
Immune reconstitution inflammatory syndrome (IRIS) in the setting of antiretroviral therapy is well described, but it is not as common in non-HIV patients; here, we present a case of immune reconstitution inflammatory syndrome presenting as acute ...
Issam A. Alawin, Bernard M. Karnath
doaj   +1 more source

Radiation‐Resistant Bacteria Deinococcus radiodurans‐Derived Extracellular Vesicles as Potential Radioprotectors

Advanced Healthcare Materials, EarlyView.
Deinococcus radiodurans‐derived extracellular vesicles (R1‐EVs) provide radioprotection against total‐body irradiation‐induced acute radiation syndrome in mice. R1‐EVs mitigate oxidative damage by scavenging free radicals, promoting intestinal repair, enhancing hematopoietic function, and modulating immune responses. This study highlights the potential
Jeong Moo Han, Godfrey Mwiti, Seo‐Joon Yeom, Jaeyoon Lim, Woo Sik Kim, Sangyong Lim, Seung‐Taik Lim, Eui‐Baek Byun   +7 more
wiley   +1 more source